Publications

Danzl, N.M., Donlin, L.T., and Alexandropoulos, K.  Regulation of Medullary Thymic Epithelial Cell Differentiation and Function by the Signaling Protein Sin. J. Exp. Med. 2010. 207(5):999-1013

Alexandropoulos, K. and Regelmann, A.G. Chat-H/CasL: A novel adapter complex that regulates T lymphocyte physiology.  Imm. Rev. 2009. 232(1):160-74.

Regelmann, A.G., Danzl, N.M., Wanjalla C., and Alexandropoulos, K. The hematopoietic isoform of Cas-Hef-1-associated signal transducer regulates chemokine-induced inside-out signaling and T cell trafficking. 2006. Immunity, 25:907-918.

Natarajan, M., Stewart Jr., J.E., Golemis, E., Pugacheva, E., Alexandropoulos, K., Grammer, J.R., and Gladson, C.L. HEF1 is a necessary and specific downstream effector of FAK that   promotes the migration  of glioblastoma cells. 2006. Oncogene, 25:1721-1732. 

Donlin, L.T., Danzl, N., Wanjalla, C., and Alexandropoulos, K. 2005. Deficiency in Expression of the Signaling Protein Sin/Efs Leads to T lymphocyte Activation and Mucosal Inflammation. 2005. Mol. Cell. Biol.  25:11035-11046.

Xing, L., Donlin, L.T., Miller, R.H., and Alexandropoulos, K.  The Adapter Molecule Sin     Regulates T-Cell-Receptor-Mediated Signal Transduction by Modulating Signaling Substrate Availability. 2004. Mol. Cell. Biol.  24: 4581-4592.

Alexandropoulos, K., Donlin, L.T., Xing, L. and Regelmann, A.G. Sin: Good or Bad? A T- lymphocyte perspective. 2003. Immonol. Rev. 192: 181-195.

Donlin, L.T., Roman, C.A., Adlam, M., Regelmann, A.G., and Alexandropoulos, K. Defective thymocyte maturation by transgenic expression of a truncated form of the adapter molecule and Fyn substrate, Sin.  2002. J. Immunol.  169:6900-6909.

Xing L., Ge, C, Zeltser R, Maskevitch GR, Mayer, BJ, and Alexandropoulos K.  c-Src signaling induced by the adapters Sin and Cas is mediated by the Rap1 GTPase. 2000. Mol. Cell. Biol. 20:7363-7377.