Publications

Rapti K, Louis-Jeune V, Kohlbrenner E, Ishikawa K, Ladage D, Zolotukhin S, Hajjar RJ, Weber T. Neutralizing Antibodies Against AAV Serotypes 1, 2, 6, and 9 in Sera of Commonly Used Animal Models. Molecular Therapy 2012; 20: 73-83.

Nonnenmacher M, Weber T. Adeno-Associated Virus 2 Infection Requires Endocytosis through the CLIC/GEEC Pathway. Cell Host and Microbe 2011; 10: 563-576.

Zeltner N, Kohlbrenner E, Clément N, Weber T, Linden RM. Near-perfect infectivity of wild-type AAV as benchmark for infectivity of recombinant AAV vectors. Gene Ther. 2010 Jul; 17(7):872-9. Epub 2010 Mar 25.

Hirosue S, Senn K, Clement N, Nonnenmacher M, Gigout L, Linden RM, Weber T. Effect of inhibition of dynein function and microtubule-altering drugs on AAV2 transduction. Virology 2007; 367:10-8.

Hirosue S, Weber T. pH-Dependent Lytic Peptides Discovered by Phage Display. Biochemistry 2006 May 23; 45(20):6476-6487.

Gigout L, Rebollo P, Clement N, Warrington KH, Jr., Muzyczka N, Linden RM, Weber T. Altering AAV tropism with mosaic viral capsids. Mol Ther 2005; 11:856-65.

Tucker WC, Weber T, Chapman ER. Reconstitution of Ca2+-regulated membrane fusion by synaptotagmin and SNAREs. Science 2004 Apr; 304(5669):435-438.

Murrell M, Porotto M, Weber T, Greengard O, Moscona A. Mutations in human parainfluenza virus type 3 hemagglutinin-neuraminidase causing increased receptor binding activity and resistance to the transition state sialic acid analog 4-GU-DANA (Zanamivir). J Virol 2003 Jan; 77(1):309-317.

Weber T, Parlati F, Mcnew JA, Johnston RJ, Westermann B, Sollner TH, Rothman JE. SNAREpins are functionally resistant to disruption by NSF and alphaSNAP. J Cell Biol 2000 May 29; 149(5):1063-1072.

Mcnew JA, Weber T, Parlati F, Johnston RJ, Melia TJ, Sollner TH, Rothman JE. Close is not enough: SNARE-dependent membrane fusion requires an active mechanism that transduces force to membrane anchors. J Cell Biol 2000 Jul 10; 150(1):105-117.

Fukuda R, Mcnew JA, Weber T, Parlati F, Engel T, Nickel W, Rothman JE, Sollner TH. Functional architecture of an intracellular membrane t-SNARE. Nature 2000 Sep 14; 407(6801):198-202.

Nickel W, Weber T, Mcnew JA, Parlati F, Sollner TH, Rothman JE. Content mixing and membrane integrity during membrane fusion driven by pairing of isolated v-SNAREs and t-SNAREs. Proc Natl Acad Sci USA 1999 Oct 26; 96(22):12571-12576.

Parlati F, Weber T, Mcnew JA, Westermann B, Sollner TH, Rothman JE. Rapid and efficient fusion of phospholipid vesicles by the alpha-helical core of a SNARE complex in the absence of an N-terminal regulatory domain. Proc Natl Acad Sci USA 1999 Oct 26; 96(22):12565-12570.

Weber T, Zemelman BV, McNew JA, Westermann B, Gmachl M, Parlati F, Sollner TH, Rothman JE. SNAREpins: Minimal Machinery for Membrane Fusion. Cell 1998 Mar 20; 92(6):759-772.


Contact Us

Thomas Weber, PhD
Tel: 212-241-0282
Send e-mail

FACILITIES
Atran-Berg Building
Room AB 3-37
1428 Madison Avenue
New York, NY 10029