Research at Yue Laboratory

Molecular, Cellular, Behavioral Biology, and Translational Research in Neurodegeneration

Yue Laboratory’s primary research interests encompass molecular and cellular pathways for autophagy-lysosome degradation, synaptic vesicle trafficking, neuroinflammation, and protein/lipid kinase signaling in neuropathogenesis.

Research Areas:

  • Autophagy in neurons and neurodegenerative diseases

  • The regulation of autophagy and endocytosis by protein kinases and lipid kinases

  • The cellular and molecular mechanism for Parkinson's disease

  • Neuroinflammatory pathways in Parkinson's disease

  • The biology, pathophysiology and pharmacology of LRRK2 kinase in Parkinson's

  • Genetic animal model development for neurodegenerative diseases