Recognition and Publications

Sarah F Funderburk , QingJun Wang, and Zhenyu Yue  (2010) The Beclin 1-VPS34 complex - at the crossroads of autophagy and beyond.  Trends in Cell Biology.  20(6):355-62.  PMID 20356743.

Xianting Li, Jyoti C. Patel, Jing Wang, Marat V. Avshalumov, Charles Nicholson, Joseph D. Buxbaum, Gregory A. Elder, Margaret E. Rice and Zhenyu Yue  (2010)   Enhanced Striatal Dopamine Transmission and Motor Performance with LRRK2 Overexpression in Mice is Eliminated by familial Parkinson’s Disease Mutation G2019S.   Journal of Neuroscience  30(5):1788-1797.  PMID 20130188.

Yun Zhong, Qing-Jun Wang, Xianting Li, Brian T. Chait, Nathaniel Heintz and Zhenyu Yue (2009)   Distinct Regulation of Autophagic Activity by Novel Components Atg14L and Rubicon in Beclin 1-Vps34/phosphatidylinositol (PtdIns) 3-kinase complex. Nature Cell Biology   11(4):468-76.  PMID 19270693.

Masaaki Komatsu, Satoshi Waguri, Masato Koike, Yu-shin Sou, Takashi Ueno, Taichi Hara, Noboru Mizushima, Jun-ichi Iwata, Junji Ezaki, Shigeo Murata, Jun Hamazaki, Yasumasa Nishito, Shun-ichiro Iemura, Tohru Natsume, Toru Yanagawa, Junya Uwayama, Eiji Warabi, Hiroshi Yoshida, Tetsuro Ishii, Zhenyu Yue, Yasuo Uchiyama, Eiki Kominami and Keiji Tanaka   (2007)   Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice.   Cell   131 (6):1149-63.  PMID 18083104.

Xianting Li, Yin-Cai Tan, Shibu Poulose, C. Warren Olanow, Xin-Yun Huang and Zhenyu Yue  (2007) Leucine-Rich Repeat Kinase 2 (LRRK2)/PARK8 Possesses GTPase Activity That is Altered in Familial Parkinson’ Disease R1441C/G Mutants.  Journal of Neurochemistry   103 (1), 238–247.  PMID 17623048.

Masaaki Komatsu, QingJun Wang, Gay Holstein, Eiki Kominami, Brian Chait, Keiji Tanaka, Zhenyu Yue (2007) Essential role for autophagic protein Atg7 in the maintenance of axonal homeostasis and prevention of axonal degeneration.   Proc. Natl. Acad. Sci. USA, 104 (36): 14489-14494.  PMID 17726112.

QingJun Wang, Yaomei Ding, Stave Kolhz, Noboru Mizushima, Brian Chait, Yun Zhong, Nat Heintz and Zhenyu Yue (2006) Induction of autophagy in axonal dystrophy and degeneration.    Journal of Neuroscience 26(31):8057-8068. PMID 16885219.

Zhenyu Yue, Victor Jin, Chingwen Yang, Arnold Levine and Nathaniel Heintz (2003)  Beclin1, an autophagy gene essential for early embryonic development, is a haplo-insufficient tumor suppressor.  Proc. Natl. Acad. Sci. USA, 100 (25):15077-15082.  PMID  14657337.

Zhenyu Yue, Antony Horton, Monica Bravin, Philip L. DeJager, Fekrije Selimi, and Nathaniel Heintz (2002) A Novel Protein Complex linking the delta 2 Glutamate Receptor (GluRdelta2) and Autophagy: Implications for Neurodegeneration in Lurcher Mice. Neuron35 (5):921-33.  PMID 12372286.