Research and Clinical Trials

Research

  • Body Composition and the Metabolic Syndrome in Cushing's Disease. This is a longitudinal cohort study of patients with Cushing’s disease, which assesses the role of excess cortisol in the regulation of adipose tissue, appetite, and metabolic profile.
    Recruiting Status: Enrollment is open.

  • Pathogenesis of Corticotroph Tumor Development. This study investigates mechanisms of ACTH tumor development.

  • Long-Term Risk of Treated Cushing's Disease. This is an ongoing database and long-term follow up study of patients with Cushing’s disease.

  • Characterization of Treatment and Outcomes in Patients with Prolactinomas. This is an ongoing database and long-term follow up study of patients with prolactinomas.
    Recruiting Status: Enrollment is open.

Eliza B. Geer, MD, is the principal investigator for the above studies.

Clinical Trials

  • A randomized, double-blind, multi-center, phase III study to evaluate the efficacy and safety of pasireotide LAR in patients with Cushing’s disease. This study evaluates the efficacy and safety of two dosing regimens of pasireotide, a new medical therapy for patients with Cushing’s disease.
    Recruiting Status: Enrollment is open.

  • An acromegaly, open-label, multi-center, safety monitoring program for treating patients with SOM230 (pasireotide) LAR, who have need to receive medical therapy (ACCESS). This study offers medical therapy with pasireotide for patients with acromegaly.
    Recruiting Status: Enrollment is open.

  • An Open-label study to assess the safety and efficacy of COR-003 (2S, 4R-Ketoconazole) in the treatment of endogenous Cushing’s Syndrome. This study evaluates the safety and efficacy of a new medical therapy for patients with Cushing's syndrome.  
    Recruiting Status: We are opening enrollment for this trial in August, 2014.

  • Glucocorticoid Receptor Blockade with Mifepristone in Patients with Mild Adrenal Hypercortisolism. This study evaluates the efficacy and safety of medical therapy with mifepristone for patients with mild adrenal Cushing’s disease.
    Recruiting Status: Enrollment is open.

To learn more about the clinical trials, please visit: http://clinicaltrials.gov/.

If you are interested in participating in one of these studies, please call 212-241-7975 to make an appointment with Dr. Geer.

 


Contact Us

Eliza B. Geer, MD
Tel: 212-241-7975
Fax: 212-423-0508
Send e-mail

Mount Sinai Faculty Practice
5 East 98th Street
7th floor
New York, NY 10029