Frequently Asked Questions

How can the Human Immune Monitoring Core help your research?

Q:  I want to know what happens to the immune system when I am administering a new drug, treatment, chemotherapy, or radiation.

A:  We are highly experienced in measuring differences in cytokines, in the serum or other fluids, between cohorts as well as isolating RNA from samples for sequencing. The HIMC can compare serum antibody profiles to self-antigens in two populations. We can look at differences in regulatory T cells, myeloid-derived suppressor cells (MDSC), lymphocytes, etc. between cohorts by collecting peripheral mononuclear cells from blood or other sites.

Q:  I need to collect immunological data to correlate with defined characteristics from patients in my clinical trial.

A: We are highly experienced in measuring differences in cytokines, in the serum or other fluids, between cohorts as well as isolating RNA from samples for sequencing. The HIMC can compare serum antibody profiles to self-antigens in two populations. We can look at differences in regulatory T cells, myeloid-derived suppressor cells (MDSC), lymphocytes, etc. between cohorts by collecting peripheral mononuclear cells from blood or other sites.

Q:  I would like to increase the consistency of immune monitoring in our clinical trials, but already have an experienced team of technical staff to process our samples.

A: The HIMC can perform flow cytometric acquisition on samples that have been prepared and stained. Our equipment is meticulously calibrated and maintained to provide consistent readings. Our staff can also assist with the development of Standard Operating Procedures and quality control procedures.

Q:  I am vaccinating patients with an antigen, how can HIMC help?

A:  The HIMC can measure serum or plasma antibody responses specific for the antigen. We can also look for immune responses to unrelated antigens following immunization, explained by recognition of other targets related to the tumor or virus.

Q:  I may correlate immune responses in the future, and would like to bank immune cells from our cohort.

The HIMC can process and cryopreserve plasma, serum and peripheral blood mononuclear cells to ensure viability of cells for future studies.

Q:  I do not have immune-related questions, how can I use the HIMC?

A: The HIMC can process and store blood for a variety of applications. The HIMC can sort human cells, and works closely with the genomic core to prepare samples for genomic analysis. Other biological fluids or tissue samples may be accepted.  

The HIMC performs Luminex assays, which allows for the measurement of panels of metabolic hormones, gut hormones, adipokines, stem cell markers, cell signaling molecules in cell extracts, and cardiovascular disease biomarkers to name a few.

Contact Us

Please contact us for consultation:

Human Immune Monitoring Core (HIMC)
Hess Center for Science and Medicine
1470 Madison Avenue
5th Floor, Rooms 310/313
New York, New York 10029

Send e-mail
Tel: 212-824-9354