Dean's Healthcare System Team Science Award
The Annual Dean’s Healthcare System Award, sponsored by Conduits, the Institute for Translational Sciences, has been established to acknowledge and underscore the emerging importance of interdisciplinary teams to the translation of research discoveries into clinical applications.
Winner: DEFINE-FMD Team - Jason Kovacic, MD, PhD, Jeffrey W. Olin, DO, Antonio F. Di Narzo, PhD , Valentina d’Escamard, PhD, Daniella Kadian-dodov, MD, Haoxiang Cheng, PhD, Annette King, RN, ANP, Bhargravi Vonguru, MS , Emir Bander, MD, Allison Thomas, MS , Rihab Bouchareb, PhD, Sander Florman, MD, Johan LM Björkegren, MD, PhD, Manuel Mayr MD, PhD, and Ke Hao, PhD
Description: Fibromuscular dysplasia (FMD) is a poorly understood disease that predominately affects women and may result in serious consequences including stroke and myocardial infarction. Although first reported in 1938, there are limited treatments available and little is known about its cause. To address the lack of understanding, in 2013 we assembled a multi-disciplinary team and initiated the DEFINE-FMD study - a large, functional ‘omics study of the genetic and molecular basis of FMD. Our close-knit and collaborative team approach has already shed light on the pathology of FMD, allowing us to identify several disease-causal candidates and to begin to develop a blood-based test for this disease.