Brian D Brown

Brian D Brown, PhD

  • PROFESSOR | Genetics and Genomic Sciences
  • PROFESSOR | Dermatology

Research Topics:

Antigen Presentation, Autoimmunity, Cancer, Cellular Immunity, Dendritic Cells, Gene Discovery, Gene Expressions, Gene Regulation, Gene Therapy, Gene editing, Genomics, Immunological Tolerance, Immunology, Inflammation, Macrophage, Molecular Biology, RNA, RNA Splicing & Processing, Stem Cells, T Cells, Tolerance, Transcriptional Activation and Repression

Dr. Brian Brown is broadly trained in molecular and cellular biology with a strong focus on immunology and translational medicine. His training began with his doctoral studies in Canada and his work to establish ways to overcome the immune response hindering gene therapy. He subsequently did his postdoctoral studies in Italy where he helped develop a new platform for controlling gene expression, which has led to improvements in experimental treatments for genetic disease, cancer, and viral infection. Dr. Brown's lab is now working to identify the factors that control immunity and tolerance, and translate these findings in to strategies that can be used to turn the immune system against cancer.  In 2008 Dr. Brown joined the faculty of Mount Sinai as an Assistant Professor and he was promoted to full Professor with tenure in 2018.  In 2016 he becamse the Associate Director of Mount Sinai's Immunology Institute. Dr. Brown works with the Department of Genetics and Genomic Sciences and the Icahn Institute for Data Science and Genomic Technology.

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Multi-Disciplinary Training Areas

Genetics and Data Science [GDS], Immunology [IMM]


BSc, University of Guelph

Fellowship, San Raffaele Scientific Institute

PhD, Queen's University