Douglas S. Bush, MD
- ASSISTANT PROFESSOR | Pediatrics, Pulmonary and Critical Care
Dr. Douglas Bush is an Assistant Professor of Pediatrics in the Division of Pediatric Pulmonology in the Jack and Lucy Clark Department of Pediatrics at the Icahn School of Medicine at Mount Sinai and the Mount Sinai Kravis Children's Hospital. After completing his undergraduate studies at Union College and obtaining his medical degree from St. George’s University School of Medicine, he went on to complete his pediatric residency at Cohen Children’s Medical Center and his pediatric pulmonology fellowship at Children’s Hospital Colorado, part of the University of Colorado. Dr. Bush has studied the genetic and molecular contributions to developing pulmonary hypertension in children with Down syndrome. In particular, he has studied the effects of genetic over-expression of chromosome 21 specific anti-angiogenic factors and their contribution to abnormal lung vascular and airway development.
Although Dr. Bush has expertise in all aspects of pediatric pulmonary disease, he has additional and specific interests in pulmonary hypertension more broadly, severe/refractory asthma, chronic lung disease, rare and interstitial lung disease, technology dependence (tracheostomy and/or chronic ventilator dependence) and other developmental lung disorders such as bronchopulmonary dysplasia.
American Board of Pediatrics
MD, St. George's University
Residency, Pediatrics, Cohen Children's Medical Center
Fellowship, Pediatric Pulmonary, Children's Hospital Colorado
ATS Best of Pediatrics; Research Platform Presentation
ATS Abstract Scholarship
ATS Assembly on Pediatrics Scientific Abstract Award
Dr. Bush has focused on airway and pulmonary vascular complications in children with Down syndrome. His research aims to improve our understanding of the genetic contributions from the 21st chromosome towards the development of lung hypoplasia and pulmonary hypertension in the Down syndrome population. More specifically, he is interested in the effects of over-expressed chromosome 21 encoded anti-angiogenic factors on lung and vascular development in children with Down syndrome. In addition to his work with the Down syndrome population, his ongoing work (in conjunction with Dr. Alfin Vicencio) focuses on the airway microbiome and fungal disease in severe, refractory asthmatics.