Ernesto Guccione

Ernesto Guccione, PhD

  • SENIOR FACULTY | Oncological Sciences
  • SENIOR FACULTY | Pharmacological Sciences

Research Topics:

Cancer, Developmental Biology, Epigenetics, Post-Transcriptional Processing

During my PhD at the International Center for Genetic Engineering Biotechnology (ICGEB) I have studied the oncogenic functions of HPV E6/E7 viral proteins and the relevance of splicing in regulating E6 functions.

During my postdoctoral work at the European Institute of Oncology I studied the role of chromatin in defining c-MYC target site recognition. I have also identified PRMT6, a member of the Protein Arginine MethylTransferase (PRMT) family, as an important enzyme regulating transcriptional repression.

I am currently an Associate Professor in the department of Oncological Sciences at Icahn School of Medicine at Mount Sinai and a Snr.PI and Coordinator of the Program in Epigenetics and Diseases at IMCB in Singapore.


MS, University of Bologna

PhD, International School for Advanced Studies (SISSA)/International Center for Genetic Engineering Biotechnology (ICGEB)

Post Doc, European Institute of Oncology