Isabelle M Germano, MD, MBA
- PROFESSOR | Neurosurgery
- PROFESSOR | Neurology
- PROFESSOR | Oncological Sciences
Specialties:Neurosurgery, Cancer (Oncology)
Research Topics:Anti-Tumor Therapy, Apoptosis/Cell Death, Autophagy, Brain, Cancer, Cellular Differentiation, Gene Expressions, Gene Therapy, Metastasis, Migration, Molecular Biology, Neuroscience, Seizure, Stem Cells, Translation, Tumor Suppressor Genes, Tumorigenesis
Dr. Germano joined the faculty at Mount Sinai in 1993. She is Director of The Mount Sinai Comprehensive Brain Tumor Program, an advanced multidisciplinary program based on computer-assisted image-guided neurosurgery and brain mapping to accomplish minimally invasive procedures and treatment of brain tumors. She is also Co-Director of the Radiosurgery Program.
Watch a video about Dr. Germano or learn more about her by visiting the Neurosurgery Tumors website.
Dr. Germano's specialty interests include brain tumors, computer-assisted image-guided neurosurgery, epilepsy surgery and radiosurgery. She is one of the pioneers of computer-assisted image-guided neurosurgery. This sophisticated technology, including the Novalis Shaped Beam Surgery, is used to perform minimally invasive surgery for patients with brain tumors, epilepsy, Parkinson's disease and movement disorders. Active in national neurosurgery organizations, Dr. Germano has served as an executive committee member for the Congress of Neurosurgery (CNS), as a member of the Board of Directors for the American Association of Neurological Surgeons (AANS), as an executive committee member of the AANS/CNS Joint Section on Tumors, and as a scientific program member for the AANS, CNS, and the American Epilepsy Society. For the past five years she has directed a course, "Advanced Techniques in Image-Guided Brain and Spine Surgery," for neurosurgeons from around the country.
Dr. Germano and her work diagnosing and treating brain tumors were profiled in The Daily News feature The Daily Check Up. View the PDF.
Dr. Germano was chosen to give the Charles A. Elsberg Lecture, the first woman to receive this honor since the lecture’s establishment 67 years ago. Read about her honor.
- Acoustic Neuroma
- Brain Metastasis
- Brain Tumor And Brain Cancer
- Brain, Spine Tumors
- Glioblastoma Multiforme
- Pituitary Adenoma
- Stereotactic Radiosurgery
Multi-Disciplinary Training AreaDevelopment, Regeneration, and Stem Cells [DRS]
MD, University of Turin Medical School
Residency, Surgery, Univ. of California, San Francisco
Residency, Neurosurgery, Univ. of California, San Francisco
Residency, Neurosurgery, Albert Einstein College of Medicine
Fellowship, Neurosurgery, University of Zurich
Fellowship, Neurosurgery, Montreal Neurological Institute
Charles A. Elsberg, MD Lecturer
Cullman Family Award for Excellence in Physician Communication
Most Compassionate Top 10 Doctors
Leksell Radiosurgery Award
Leksell Radiosurgery Award
Technology Development Award
Neurological Devices Voting Member
Research grant: Brain tumors and gene transfer
Brain Tumor Research
Life Time Member
New York State Certificats of Recognition, Dedication and Service to the Italians Culture and Community
Certificate of Excellence in Youth Education
Neurosurgery Research Award
America's Top Cancer Doctors
Best Doctors Of New York
Top Doctors New York Metro Area
Mary Putnam Jacobi Award
W. Penfield Award
Translational research for malignant brain tumors
The main focus of the laboratory is to investigate new strategies for adjuvant treatment of malignant brain tumors. With the support from the National Institutes of Health, NIH, private foundations and Industry, the laboratory has been very productive in investigating new promising modalities and compound to kill brain tumor cells. Embryonic stem cells are currently used in animal models to transfer genes to brain tumors.
Image-guide computer-assisted neurosurgery
One of the pioneers in this field, Dr. Germano continues to collaborate with the industry in making neurosurgical resections more accurate and less invasive.
Brain Tumor and Gene Therapy Laboratory