James C Iatridis, PhD
- PROFESSOR | Orthopedics
- PROFESSOR | Neurosurgery
Research Topics:Biomechanics/Bioengineering, Developmental Biology, Inflammation, Mathematical Modeling of Biomedical Systems, Orthopaedics, Pharmacology, Regeneration, Spinal Cord, Tissue Engineering, Translation
Dr. Iatridis is Professor and Vice Chair for Research in the Leni and Peter W. May Department of Orthopaedics at the Icahn School of Medicine at Mount Sinai in New York City. Dr. Iatridis joined Mount Sinai in 2010 to drive his spine research in translational directions. Dr. Iatridis is Vice Chair for Reseach of Orthopaedics and the Director of the Spine Research Program of the Mount Sinai Health System. Dr. Iatridis graduated from Franklin and Marshall College with a B.A. in Physics, and then completed his B.S., M.S. and Ph.D. from Columbia University in Mechanical Engineering. He spent nearly 15 years at University of Vermont as post-doc and then faculty member in the School of Engineering (Mechanical & Biomedical Engineering) with secondary appointment in the Department of Orthopaedics.
For more information, please see Iatridis Lab and Orthopaedic Research Lab pages.
Multi-Disciplinary Training AreasArtificial Intelligence and Emerging Technologies in Medicine [AIET], Development Regeneration and Stem Cells [DRS], Neuroscience [NEU], Pharmacology and Therapeutics Discovery [PTD]
BA, Franklin and Marshall College
PhD, Columbia University
Post-doctoral Fellowship, University of Vermont
Henry Farfan Award
Berton Rahn Research Prize
Presidential Early Career Award for Scientists and Engineers (PECASE)
Macnab LaRocca Fellowship
Dr. Iatridis’ research focus is on the development of early and minimally invasive treatments to prevent or repair injured and degenerated intervertebral discs. Dr. Iatridis received grants from the NIH, Whitaker Foundation, and AO Foundation. He was awarded a Presidential Early Career Award for Scientists and Engineers (PECASE) in 2008, and the Berton Rahn Research Prize of the AO Research Fund in 2009 and the Henry Farfan Award for Spine Basic Sciences of the North American Spine Society in 2015. Dr. Iatridis is very active in his research community having reviewed for over 20 journals and 6 funding agencies, he currently serves on the editorial board of 2 journals. Dr. Iatridis served as inaugural Chair of the Spine Section of the Orthopaedic Research Society, President of the Orthopaedic Research Society, and previously served as member and Chair of the NIH Skeletal Biology Structure and Regeneration Study Section.
Spine Mechanobiology, Tissue Engineering and Regenerative Medicine
Our laboratory is interested in investigations of functional changes in the spine in response to loading and injury, and investigations of promising therapeutic techniques to promote spine health and repair. Our investigations span biomechanics, mechanobiology, tissue engineering, anti-inflammatory and cellular therapies. Through our animal, cell, and organ culture studies we have a focus on models of injury and repair with high relevance to human clinical conditions. Our research balances exploration of fundamental mechanisms and translation with appreciation for the development and maturation processes in human joints that promote health and disease processes.
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.
Dr. Iatridis did not report having any of the following types of financial relationships with industry during 2022 and/or 2023: consulting, scientific advisory board, industry-sponsored lectures, service on Board of Directors, participation on industry-sponsored committees, equity ownership valued at greater than 5% of a publicly traded company or any value in a privately held company. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.
Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.