Education
PhD, Cornell University
My research interests focus on both statistical theory and applications.
A major area of interest is the combinatorial construction of new experimental designs. Specifically, work is being done on the mathematical construction of sets of mutually orthogonal frequency rectangle designs, which are generalizations of latin square designs. In addition, work is underway on the construction of asymmetrical orthogonal arrays, an area of discrete mathematics that plays a fundamental role in fractional factorial experimental designs.
I am also working on the statistical design and analysis of cancer clinical trials. Emphasis is on the proper design and analysis of Phase I and Phase II clinical trials, as well as laboratory studies; and the application of stopping rules, multistage designs, and classical experimental design theory to cancer clinical and laboratory study design.
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.
Dr. Mandeli did not report having any of the following types of financial relationships with industry during 2022 and/or 2023: consulting, scientific advisory board, industry-sponsored lectures, service on Board of Directors, participation on industry-sponsored committees, equity ownership valued at greater than 5% of a publicly traded company or any value in a privately held company. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.
Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.