John P Sfakianos

John P Sfakianos, MD




John Sfakianos, MD, is Assistant Professor of Urology and Urologic Oncology at the Icahn School of Medicine at Mount Sinai. His clinical focus includes treating patients with urothelial cancers of the upper urinary tract and bladder. He offers patients treatment options through his expertise in treating urologic conditions using open, laparoscopic and robotic techniques. He performs both robotic and open nephroureterectomies, partial cystectomies and cystectomies and forms urinary diversions including ileal conduits, continent catherizable pouches, and continent urinary diversions (ileal neobladder). His clinical interests and skills also include surgical treatment of patients with kidney, prostate, testicular and penile cancers.

Dr. Sfakianos is a firm believer in a multidisciplinary approach to cancer care. He works closely with his colleagues in medical oncology and radiation oncology to provide a customized, integrated and innovative approach to treatment of patients with urologic cancers. His research focuses on the approach to treating urothelial and prostate cancers in personalized medicine, including genomic analyses of tumors, to predict risk and response to therapy. In laboratory research, he is using mouse models in prostate and bladder cancer to identify novel treatments. Dr. Sfakianos has published over 20 research articles in peer-reviewed publications, written book chapters on urothelial carcinoma and is a reviewer for the Journal of Urology and Urologic Oncology.

Dr. Sfakianos received his medical degree from the School of Medicine and Biomedical Sciences at Buffalo and completed his internship and residency at the State University of New York at Downstate Medical Center. He went on to complete a fellowship in Urologic Oncology accredited by the Society of Urologic Oncology at the Memorial Sloan Kettering Cancer Center.


American Board of Urology

Clinical Focus

  • Prostate Cancer
  • Prostate Cancer Screening
  • Prostate Laser Procedures
  • Prostate-Specific Antigen (PSA) Test
  • Prostatectomy
  • Pyeloplasty
  • Radical Cystectomy
  • Robotic Kidney Surgery
  • Robotic Prostate Surgery
  • Testicular Cancer
  • Ultrasound
  • Ureteroscopy
  • Urinary Fistula
  • Vasectomy Reversal


MD, University at Buffalo

Internship, Surgery (General Surgery), SUNY Downstate Medical Center

Residency, Urology, SUNY Downstate Medical Center

Fellowship, Urologic Oncology, Memorial Sloan-Kettering Cancer Center

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