Kirk Campbell, MD
img_Kirk Campbell
PROFESSOR | Medicine, Nephrology
PROFESSOR | Pharmacological Sciences
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Specialties
Internal Medicine, Nephrology
Multi-Disciplinary Training Area
Development Regeneration and Stem Cells [DRS], Disease Mechanisms and Therapeutics (DMT)
Kidney podocytes are the target cells for injury in human glomerular disease, a significant cause of end stage kidney failure. Primary and secondary pathogenic processes affecting podocytes account for 90% of end-stage kidney disease at a cost of 20 billion dollars per year in the US. A reduction in podocyte number (podocytopenia) directly correlates with the progression of several proteinuric kidney diseases including focal segmental glomerulosclerosis (FSGS), IgA nephropathy and diabetic nephropathy. Despite significant advances in the characterization of the molecular architecture of podocytes, the mechanisms underlying their survival, injury and loss remain poorly understood. Validated therapeutic targets are scarce and there are currently no podocyte-specific drugs commercially available. The overall goal of our research program is to enhance the pipeline of putative therapeutic targets available to tackle human glomerular disease by elucidating the details and functional significance of key signaling pathways that regulate podocyte injury and survival. We utilize cell-based assays and rodent models to identify and characterize key mediators of glomerular disease progression. Please go to The Campbell Laboratory at https://campbell-lab.org/

MD, University of Connecticut School of Medicine

Residency, Internal Medicine, Yale New Haven Hospital

Fellowship, Nephrology, Mount Sinai Hospital

Certifications

American Board of Internal Medicine
Publications

Selected Publications

The chromatin landscape of healthy and injured cell types in the human kidney. Debora L. Gisch, Michelle Brennan, Blue B. Lake, Jeannine Basta, Mark S. Keller, Ricardo Melo Ferreira, Shreeram Akilesh, Reetika Ghag, Charles Lu, Ying Hua Cheng, Kimberly S. Collins, Samir V. Parikh, Brad H. Rovin, Lynn Robbins, Lisa Stout, Kimberly Y. Conklin, Dinh Diep, Bo Zhang, Amanda Knoten, Daria Barwinska, Mahla Asghari, Angela R. Sabo, Michael J. Ferkowicz, Timothy A. Sutton, Katherine J. Kelly, Ian H. De Boer, Sylvia E. Rosas, Krzysztof Kiryluk, Jeffrey B. Hodgin, Fadhl Alakwaa, Seth Winfree, Nichole Jefferson, Aydın Türkmen, Joseph P. Gaut, Nils Gehlenborg, Carrie L. Phillips, Tarek M. El-Achkar, Pierre C. Dagher, Takashi Hato, Kun Zhang, Jonathan Himmelfarb, Matthias Kretzler, Shamim Mollah, Blue Lake, Alexander Morales, Isaac Stillman, Stewart Lecker, Steve Bogen, Ashish Verma, Guanghao Yu, Insa Schmidt, Joel Henderson, Laurence Beck, Pranav Yadati, Sushrut Waikar, Afolarin A. Amodu, Shana Maikhor, Titlayo Ilori, Mia R. Colona, Astrid Weins, Gearoid McMahon, Nir Hacohen, Anna Greka, Jamie L. Marshall, Paul J. Hoover, Vidya S. Viswanathan, Dana Crawford, Mark Aulisio, William Bush, Yijiang Chen, Anant Madabhushi, Charles O’Malley, Crystal Gadegbeku, Dianna Sendrey, Emilio Poggio, John O’Toole, John Sedor, Jonathan Taliercio, Lakeshia Bush, Leal Herlitz, Ellen Palmer, Jane Nguyen, Kassandra Spates-Harden, Leslie Cooperman, Stacey Jolly, Carissa Vinovskis, Andrew Bomback, Jonathan Barasch, Krzysztof Kiryluk, Paul Appelbaum, Vivette D’Agati, Cecilia Berrouet, Karla Mehl, Maya Sabatello, Ning Shang, Olivia Balderes, Pietro A. Canetta, Satoru Kudose, Joana de Pinho Gonçalves, Lukasz Migas, Raf Van de Plas, Roy Lardenoije, Laura Barisoni, Helmut Rennke, Abraham Verdoes, Angela Sabo, Debora Lidia Gisch, James Williams, Katherine Kelly, Kenneth Dunn, Michael Eadon, Michael Ferkowicz, Pierre Dagher, Seth Winfree, Sharon Bledsoe, Stephanie Wofford, Tarek Ashkar (El-Achkar), Timothy Sutton, William Bowen, Austen Slade, Elizabeth Record, Yinghua Cheng, Yashvardhan Jain, Bruce Herr, Ellen Quardokus, Ashley Wang, Celia Pamela Corona Villalobos, Chirag Parikh, Mohamed Atta, Steven Menez, Yumeng Wen, Alan Xu, Lauren Bernard, Camille Johansen, Sarah Chen, Sylvia Rosas, Isabel Donohoe, Jennifer Sun, Richard Knight, Anna Shpigel, Jack Bebiak, John Saul, Joseph Ardayfio, Robert Koewler, Roy Pinkeney, Taneisha Campbell, Evren Azeloglu, Girish Nadkarni, John He, Joji Tokita, Kirk Campbell, Marissa Patel, Sean Lefferts, Srinivas Ravi Iyengar, Stephen Ward, Steven Coca, Cijang He, Yuguang Xiong, Pottumarthi Prasad, Brad Rovin, John P. Shapiro, Samir Parikh, Sethu M. Madhavan, Jessica Lukowski, Dusan Velickovic, Ljiljana Pasa-Tolic, George (Holt) Oliver, Olga Troyanskaya, Rachel Sealfon, Weiguang Mao, Aaron Wong, Ari Pollack, Yury Goltsev, Brandon Ginley, Brendon Lutnick, Garry Nolan, Kavya Anjani, Tariq Mukatash, Zoltan G. Laszik, Baltazar Campos, Bijin Thajudeen, David Beyda, Erika Bracamonte, Frank Brosius, Gregory Woodhead, Katherine Mendoza, Nicole Marquez, Raymond Scott, Rebecca Tsosie, Milda Saunders, Adele Rike, E. Steve Woodle, Paul J. Lee, Rita R. Alloway, Tiffany Shi, Elena Hsieh, Jessica Kendrick, Joshua Thurman, Julia Wrobel, Laura Pyle, Petter Bjornstad, Nicholas Lucarelli, Pinaki Sarder, Amada Renteria, Ana Ricardo, Anand Srivastava, Devona Redmond, Eunice Carmona-Powell, James Bui, James Lash, Monica Fox, Natalie Meza, Ron Gaba, Suman Setty, Tanika Kelly, Chrysta Lienczewski, Dawit Demeke, Edgar Otto, Heather Ascani, Jeff Hodgin, Jennifer Schaub, John Hartman, Laura Mariani, Markus Bitzer, Michael Rose, Nikki Bonevich, Ninive Conser, Phillip McCown, Rachel Dull, Rajasree Menon, Rebecca Reamy, Sean Eddy, Ul Balis, Victoria Blanc, Viji Nair, Yongqun Oliver He, Zachary Wright, Becky Steck, Jinghui Luo, Renee Frey, Alyson Coleman, Dorisann Henderson-Brown, Jerica Berge, Maria Luiza Caramori, Oyedele Adeyi, Patrick Nachman, Sami Safadi, Siobhan Flanagan, Sisi Ma, Susan Klett, Susan Wolf, Tasma Harindhanavudhi, Via Rao, Amy Mottl, Anne Froment, Evan Zeitler, Peter Bream, Sara Kelley, Matthew Rosengart, Michele Elder, Paul Palevsky, Raghavan Murugan, Daniel E. Hall, Filitsa Bender, James Winters, John A. Kellum, Matthew Gilliam, Mitchell Tublin, Roderick Tan, Guanshi Zhang, Kumar Sharma, Manjeri Venkatachalam, Allen Hendricks, Asra Kermani, Jose Torrealba, Miguel Vazquez, Nancy Wang, Qi Cai, Richard Tyler Miller, Shihong Ma, Susan Hedayati, Andrew Hoofnagle, Artit Wangperawong, Ashley Berglund, Ashveena L. Dighe, Bessie Young, Brandon Larson, Brooke Berry, Charles Alpers, Christine Limonte, Christy Stutzke, Glenda Roberts, Ian de Boer, Jaime Snyder, Jimmy Phuong, Jonas Carson, Kasra Rezaei, Katherine Tuttle, Keith Brown, Kristina Blank, Natalya Sarkisova, Nichole Jefferson, Robyn McClelland, Sean Mooney, Yunbi Nam, Adam Wilcox, Christopher Park, Frederick Dowd, Kayleen Williams, Stephanie M. Grewenow, Stephen Daniel, Stuart Shankland, Annapurna Pamreddy, Hongping Ye, Richard Montellano, Shweta Bansal, Anil Pillai, Dianbo Zhang, Harold Park, Jiten Patel, Kamalanathan Sambandam, Mujeeb Basit, Natasha Wen, Orson W. Moe, Robert D. Toto, Simon C. Lee, Kavya Sharman, Richard M. Caprioli, Agnes Fogo, Jamie Allen, Jeffrey Spraggins, Katerina Djambazova, Mark de Caestecker, Martin Dufresne, Melissa Farrow, Anitha Vijayan, Brittany Minor, Gerald Nwanne, Joseph Gaut, Kristine Conlon, Madhurima Kaushal, Sabine M. Diettman, Angela M. Victoria Castro, Dennis Moledina, Francis P. Wilson, Gilbert Moeckel, Lloyd Cantley, Melissa Shaw, Vijayakumar Kakade, Tanima Arora, Sanjay Jain, Michael Rauchman, Michael T. Eadon. Nature Communications

Identification and validation of urinary CXCL9 as a biomarker for diagnosis of acute interstitial nephritis. Dennis G. Moledina, Wassim Obeid, Rex N. Smith, Ivy Rosales, Meghan E. Sise, Gilbert Moeckel, Michael Kashgarian, Michael Kuperman, Kirk N. Campbell, Sean Lefferts, Kristin Meliambro, Markus Bitzer, Mark A. Perazella, Randy L. Luciano, Jordan S. Pober, Lloyd G. Cantley, Robert B. Colvin, F. Perry Wilson, Chirag R. Parikh. Journal of Clinical Investigation

Precision Medicine in Nephrology: An Integrative Framework of Multidimensional Data in the Kidney Precision Medicine Project. Tarek M. El-Achkar, Michael T. Eadon, Matthias Kretzler, Jonathan Himmelfarb, Blue Lake, Kun Zhang, Stewart Lecker, Alexander Morales, Steve Bogen, Afolarin A. Amodu, Laurence Beck, Joel Henderson, Titlayo Ilori, Shana Maikhor, Ingrid Onul, Insa Schmidt, Ashish Verma, Sushrut Waikar, Pranav Yadati, Guanghao Yu, Mia R. Colona, Gearoid McMahon, Nir Hacohen, Anna Greka, Paul J. Hoover, Jamie L. Marshall, Mark Aulisio, William Bush, Yijiang Chen, Dana Crawford, Anant Madabhushi, Vidya S. Viswanathan, Lakeshia Bush, Leslie Cooperman, Crystal Gadegbeku, Leal Herlitz, Stacey Jolly, Jane Nguyen, Charles O'Malley, John O'Toole, Ellen Palmer, Emilio Poggio, Kassandra Spates-Harden, John Sedor, Dianna Sendrey, Jonathan Taliercio, Evren Azeloglu, Kirk Campbell, Steven Coca, Girish Nadkarni. American Journal of Kidney Diseases

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FSGS Grand Rounds
Kirk Campbell, MD

Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device, biotechnology companies, and other outside entities to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their outside financial relationships.

Below are financial relationships with industry reported by Dr. Campbell during 2023 and/or 2024. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.

Board Service

  • National Kidney Foundation

Consulting or Other Professional Services: Examples include, but are not limited to, committee participation, data safety monitoring board (DSMB) membership

  • Access for Life
  • Travere (Formerly Retrophin)
  • Calliditas Pharmaceuticals
  • Sanofi US Services Inc.
  • Chinook Therapeutics
  • Medscape

Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.