Liheng Wang

Liheng Wang, PhD

  • ASSISTANT PROFESSOR | Medicine, Endocrinology, Diabetes and Bone Disease

Research Topics:

Biochemistry, Diabetes, Liver, Metabolism, Obesity, Transcription Factors, Transcriptional Activation and Repression

Liheng Wang, Ph.D., is an assistant professor in the Department of Medicine, Division of Endocrinology, Diabetes Obesity and Metabolism Institute (DOMI) at Icahn School of Medicine at Mount Sinai.

Dr. Wang received her B.S. in Biochemistry from China Agricultural University in 2007 and Ph.D. in Nutritional and Metabolic Biology in the Institute of Human Nutrition at Columbia University in 2015. During her PhD training in Dr. Rudolph Leibel’s laboratory, she had developed the first protocol of generating human hypothalamic neurons from pluripotent stem cells (iPSCs) and further applied in studying human genetic obesity syndromes. In 2016, she joined Dr. Domenico Accili’s laboratory for her postdoctoral training. Her research was focused on mouse genetics and physiology of diabetes, particularly transcriptional regulation of liver glucose and lipid metabolism. She has published 8 first-author research articles in Cell Metabolism (2022), Journal of Hepatology (2020), Journal of Clinical Investigations (2021, 2015), and Diabetes (2019) and other journals ( /bibliography/public/). She has also received several awards, including Marija Chouinard Awards for Excellence in Research, Regeneron scholarship, NIH postdoctoral training award, and NIH K01 career development award.

In 2022, Dr. Wang joined Mount Sinai to start a new lab in DOMI.  The research of Wang lab will focus on the transcription regulation of hepatic glucose and lipid metabolism in the context of type 2 diabetes (T2D), obesity and Non-alcoholic Fatty Liver Disease (NAFLD),  aiming to discover mechanisms underlying dysregulated glucose and lipid metabolism at the molecular, cellular, tissue, and physiological levels, and eventually to develop efficient and safe interventions for preventing and treating these chronic conditions. She is currently looking for post-doctoral scientists who combine personal drive with a real desire to learn in a collaborative setting.



Multi-Disciplinary Training Area

Genetics and Genomic Sciences [GGS]


PhD, College of Physicians and Surgeons, Columbia University