Manoj K Jaiswal

Manoj K Jaiswal, PhD

  • INSTRUCTOR | Psychiatry

Manoj Kumar Jaiswal, Ph.D. is an Instructor in the Department of Psychiatry at the Icahn School of Medicine at Mount Sinai. He obtained Ph.D. training at the Georg-August University, Goettingen, Germany. His Ph.D. worked focused on [Ca2+]i and mitochondrial signaling pathways in Amyotrophic Lateral Sclerosis (ALS). Results of these studies provided evidence of a critical role of Cu, Zn superoxide dismutase (SOD1), typical for familial ALS, in the impairment of [Ca2+]mito handling and perturbation of Ca2+ homeostasis in SOD1G93A mice and cell culture models of ALS.

He completed his Postdoctoral Fellowship at the Massachusetts Institute of Technology, McGovern Center for Brain Research in Boston, MA. He then received an NIH Career Development Award and was appointed as a Career Development Fellow and later a Senior Research Fellow at the CNRM in Bethesda, MD where he studied molecular mechanisms of Traumatic Brain Injury (TBI) using 2-photon in-vivo imaging and 3-D microscopy. At CNRM he developed a minimally invasive in-vivo 2-photon imaging method and established SCALEA2/CLARITY techniques for intact volumetric 3-D imaging of optically cleared transparent mouse brains. More recently, Dr. Jaiswal was a Research Scientist in the Department of Psychiatry at the Columbia University Medical Center in New York, where he focused on studying adult neurogenesis in the brains of patients with major depression and other psychiatric disorders.

Between 1999 and 2017 Dr. Jaiswal received numerous honors and awards, including scholarships and poster awards, and was invited to present lectures and seminars. He is a member of Society for Neuroscience (SfN) and the National Neurotrauma Society (NNS). He has been the Principal Investigator of a National Institute of Health/DoD: Pilot Project entitled: “Balance between inhibition and excitation and the vascular trauma in sensory barrel cortex after TBI: in-vivo imaging approach”. He has further contributed to the field of neuroscience as a reviewer and editor for many journals, including Scientific Reports, Annals of Neurology and Frontiers in Cellular Neuroscience. He has authored numerous articles, book and book chapters on Amyotrophic Lateral Sclerosis (ALS), Motor Neuron Disease and Psychiatric Disorders.

Throughout his career, Dr. Jaiswal has demonstrated a strong commitment to research and has shown a great deal of talent and drive. Furthermore, Dr. Jaiswal is well-respected by his colleagues and has received outstanding evaluations from his mentors and peers for his collaborative spirit as well as for his generosity in supporting and fostering learning and research of trainees and students.