Margrit Wiesendanger, MD, PhD
- ASSISTANT PROFESSOR | Medicine, Rheumatology
Research Topics:Autoimmunity, B Cells, Cellular Immunity, Immunological Tolerance, Immunosuppression, Inflammation, Lupus Nephritis, T Cells
Dr. Wiesendanger is a graduate of the Albert Einstein College of Medicine in the Bronx, NY, where she earned a dual MD-PhD degree in the discipline of Immunology. She then completed a residency in Internal Medicine and fellowship in Rheumatology at the New York-Presbyterian Hospital/Columbia campus. She is board certified in both Rheumatology and Internal Medicine. She served on the faculty in the Division of General Medicine at NYPH-Columbia before joining the Division of Rheumatology at Mount Sinai Hospital in April 2015. Her patient care activities include the Mount Sinai Faculty Faculty Practice Associates and the Center for Advanced Medicine. She is the current Program Director for the rheumatology fellowship. She has received several awards, including the prestigious Daniel V. Kimberg Memorial Junior Faculty Teaching Award and the Ewig Clinical Scholar Award.
American Board of Internal Medicine
- Ankylosing Spondylitis
- Behcet's Disease
- Polymyalgia Rheumatica And Giant Cell Arteritis
- Rheumatoid Arthritis
- Sjogren's Syndrome
- Systemic Lupus Erythematosus
MD/PHD, Albert Einstein College of Medicine
Residency, Internal Medicine, Columbia University Medical Center
Fellowship, Rheumatology, Columbia University Medical Center
Ewig Clinical Scholar Award
Daniel V. Kimberg Junior Faculty Teaching Award and Lecture
Ambulatory Teacher of the Year
Elected Member, AOA
Novel Therapies for Systemic Lupus
Dr. Wiesendanger is a co-investigator in the Embrace Study: a phase 3/4, multi-center, randomized, double-blind, placebo-controlled, 52-week study to evaluate the efficacy and safety of belimumab (HGS1006) in adult subjects of black race with systemic lupus.
Winchester R, Wiesendanger M, Zhang HZ, Steshenko V, Peterson K, Geraldino-Pardilla L, Ruiz-Vazquez E, D'Agati V. Immunologic characteristics of intrarenal T cells: trafficking of expanded CD8+ T cell β-chain clonotypes in progressive lupus nephritis. Arthritis and rheumatism 2012 May; 64(5).
Winchester R, Wiesendanger M, O'Brien W, Zhang HZ, Maurer MS, Gillam LD, Schwartz A, Marboe C, Stewart AS. Circulating activated and effector memory T cells are associated with calcification and clonal expansions in bicuspid and tricuspid valves of calcific aortic stenosis. Journal of immunology (Baltimore, Md. : 1950) 2011 Jul; 187(2).
Wiesendanger M, Stanevsky A, Kovsky S, Diamond B. Novel therapeutics for systemic lupus erythematosus. Current opinion in rheumatology 2006 May; 18(3).
Iruretagoyena MI, Wiesendanger M, Kalergis AM. The dendritic cell-T cell synapse as a determinant of autoimmune pathogenesis. Current pharmaceutical design 2006; 12(2).
Wiesendanger M, Kneitz B, Edelmann W, Scharff MD. Somatic hypermutation in MutS homologue (MSH)3-, MSH6-, and MSH3/MSH6-deficient mice reveals a role for the MSH2-MSH6 heterodimer in modulating the base substitution pattern. The Journal of experimental medicine 2000 Feb; 191(3).