Matthew A Levin

Matthew A Levin, MD

  • ASSOCIATE PROFESSOR | Anesthesiology, Perioperative & Pain Medicine
  • ASSOCIATE PROFESSOR | Genetics and Genomic Sciences



Research Topics:

Bioinformatics, Genomics

Dr. Levin is a Board Certified Cardiac Anesthesiologist, Board Certified Clinical Informaticist, and Director of Research Informatics for the Department of Anesthesiology, Perioperative & Pain Medicine. He holds a joint appointment in the Department of Genetics and Genomics Sciences. Matt began his career by working for five years in Silicon Valley and the software industry during the dot-com boom. He then changed careers to pursue medicine, but never lost his passion for technology. Now he is excited to be bringing the latest innovations in systems architecture, machine learning and big data into the healthcare arena, to improve patient care and save lives. He created and directs the Department of Anesthesiology's large perioperative data warehouse, which contains detailed demographic, physiologic, and medication data for over 900,000 anesthetic cases. Dr. Levin has also been leading the initiative to build a real-time, streaming data pipeline that uses machine learning to improve the early detection of unexpected clinical deterioration among hospital patients and provide real-time "early warning" alerts to clinicians.

Through his multi-disciplinary collaborations with other researchers in the Icahn School of Medicine, Dr. Levin is pushing the boundaries of perioperative research in order to answer previously un-addressable questions on the phenotype and genotype of the response to anesthetic and surgical stress.  Dr. Levin is affiliated with The Charles Bronfman Institute for Personalized Medicine and collaborates closely with fellow IPM member Dr. Eimear Kenny.  Together they were awarded a prestigious two year starter grant (2015-2017) from the Society of Cardiovascular Anesthesiologists to investigate the Genomics of Vasoplegia, a condition of profound, persistent hypotension sometimes seen after cardiopulmonary bypass.  Dr. Levin's 2014 article "Low intraoperative tidal volume ventilation with minimal PEEP is associated with increased mortality" was recently recognized as the most cited article from 2013-2014 in the British Journal of Anaesthesia, contributing to the BJA's increase in impact factor to 5.616.


Google Scholar:   ResearchGate:  


American Board of Anesthesiology


MD, Mount Sinai School of Medicine

BS, Massachusetts Institute of Technology

Internship, Surgery, Lenox Hill Hospital

Residency, Anesthesiology, Mount Sinai Hospital

Fellowship, Cardiothoracic Anes., Mount Sinai Hospital

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