Matthew A Levin

Matthew A Levin, MD

  • ASSOCIATE PROFESSOR | Anesthesiology, Perioperative & Pain Medicine
  • ASSOCIATE PROFESSOR | Genetics and Genomic Sciences



Research Topics:

Anesthesia, Bioinformatics, Cardiovascular, Genomics

Dr. Levin is a Board Certified Cardiac Anesthesiologist, Board Certified Clinical Informaticist, Director of Research Informatics for the Department of Anesthesiology, Perioperative & Pain Medicine, and Director of the Clinical Data Science Team for the Mount Sinai Health System. He also holds a joint appointment in the Department of Genetics and Genomics Sciences and collaborates with the Icahn Institute for Data Science and Genomic Technology. Dr. Levin began his career by working for five years in Silicon Valley and the software industry during the dot-com boom. He then changed careers to pursue medicine, but never lost his passion for technology. Dr. Levin is excited to be bringing the latest innovations in systems architecture, machine learning into the healthcare arena in order to improve patient care and save lives. He created and directs the Department of Anesthesiology's large perioperative data warehouse, which contains detailed demographic, physiologic, and medication data for over 900,000 anesthetic cases. As Director of the Health System Clinical Data Science Team, he has led the initiative to build a streaming data science pipeline that enables the deployment of real-time machine learning algorithms to provide next-generation decision support and alerting to front line clinicians. 

During the COVID-19 crisis Dr. Levin has led a multi-disciplinary group to drive innovation in ventilators, data science, and operations. 

Dr. Levin's clinical research interest prior to the COVID-19 pandemic was in understanding risk factors for morbidity and mortality in perioperative period, with particular focus on intraoperative physiology and hemodynamics. He has published extensively in this area. In 2015 he was awarded a prestigious two year starter grant from the Society of Cardiovascular Anesthesiologists to investigate the Genomics of Vasoplegia, a condition of profound, persistent hypotension sometimes seen after cardiopulmonary bypass. Dr. Levin's 2014 article "Low intraoperative tidal volume ventilation with minimal PEEP is associated with increased mortality" was recently recognized as the most cited article from 2013-2014 in the British Journal of Anaesthesia, contributing to the BJA's increase in impact factor to 5.616.


Google Scholar   ResearchGate  


American Board of Preventive Medicine

American Board of Anesthesiology


MD, Mount Sinai Hospital

BS, Massachusetts Institute of Technology

Internship, Surgery, Lenox Hill Hospital

Residency, Clinical Anesthesiology, Mount Sinai Hospital

Fellowship, Cardiothoracic Anesthesiology, Mount Sinai Hospital

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