Michael Buckstein, MD, PhD
- ASSOCIATE PROFESSOR | Radiation Oncology
Michael Buckstein, M.D., Ph.D. is a radiation oncologist specializing in the treatment of gastrointestinal tumors including the esophagus, stomach, pancreas, liver, gall bladder, bile ducts, rectum, and anus as well coronary brachytherapy. He uses many advanced techniques such Intensity Modulated Radiation Therapy (IMRT), Image Guided Radiation Therapy (IGRT), Stereotactic Body Radiation Therapy (SBRT), and brachytherapy to maximize local control and cure of the cancer while minimizing radiation side effects to healthy tissue.
Dr. Buckstein graduated from Yale University and received both a medical and doctoral degree from the University of Pennsylvania School of Medicine. His Ph.D. dissertation focused on the biochemical changes that affect the growth patterns of cells. He completed his Medical Internship at Long Island Jewish Medical Center and his Residency in Radiation Oncology at the Icahn School of Medicine at Mount Sinai where he served as Chief Resident.
Dr. Buckstein’s primary research focus is attempting to identify causes and limit treatment related toxicity from radiation therapy. In addition to large retrospective reviews identifying factors involved in disease outcomes and toxicity, he is also heavily involved in projects using genomics to identify specific individuals at risk for developing adverse side effects from treatment. He was involved in a novel study identifying genetic factors predictive for the development of erectile dysfunction following radiation for prostate cancer. His work has resulted in multiple presentations at international meetings as well publication in peer reviewed journals.
PhD, University of Pennsylvania School of Medicine
MD, University of Pennsylvania
MD, University of Pennsylvania School of Medicine
Residency, Internal Medicine, Long Island Jewish Medical Center
Residency, Radiation Oncology, Mount Sinai Hospital
Roentgen Resident Research Award
Best of ASTRO Award
John G. Clark Prize
Medical Scientist Training Program Fellowship
Identifying Genetic Predictors for Radiation Treatment Related Toxicity
Dr, Buckstein is involved in mutliple projects using Genome-Wide Association Studies (GWAS) to identify individual genetic differences that might predict for the development of radiation toxicity. This will ultimately allow physicians to personalize therapy to each individual, potentially minimizing toxicity and optimizing therpeutic outcomes.
Outcomes Based Research for Gastrointestinal Malignancies
Using a variety of tools institutional and national based databases, Dr. Buckstein is involved with research attempting to identify treatment related predictors for outcomes and development of treatment related toxicities. He has a particular focus on understanding outcomes with patients who have Inflammatory Bowel Disease who develop a malignancy.
Use of Stereotactic Body Radiation Therapy and Hepatocellular Carcinomas
Dr. Buckstein is the principal investigator on a study using combination trans-arterial chemo embolization (TACE) with stereotactic body radiation therapy (SBRT) as a treatment paradigm for treating large hepatocellular carcinomas. In addition, he is actively working to safely integrate SBRT into treatment paradigms for HCC.