Miriam Merad

Miriam Merad, MD, PhD

  • PROFESSOR | Oncological Sciences
  • PROFESSOR | Medicine, Hematology and Medical Oncology

Research Topics:

Cancer, Chemokines, Dendritic Cells, Immunological Tolerance, Immunology, Lymphocytes, Macrophage, Microglia, Stem Cells, T Cells, Transplantation

Miriam Merad, M.D.; Ph.D. is the Mount Sinai Endowed professor in Cancer Immunology and the Director of the Precision Immunology Institute at Mount Sinai School of Medicine in New York. Dr. Merad also co-Directs, the Cancer Immunology program at The Mount Sinai Tisch Cancer Institute and is the Director of the Mount Sinai Human Immune Monitoring Center (HIMC).

Dr. Merad’s laboratory made seminal discoveries to our understanding of the mechanisms that control the development and functional identity of tissue resident dendritic cells and macrophages during homeostasis, and examining how these regulations are changed in cancer and inflammatory diseases. 

The overarching goal of her laboratory is to identify dysregulated pathways in macrophages and dendritic cells that can be harnessed to treat Cancer using both genetically engineered mouse models and human lesions to address these questions. To expand the understanding of immune cells contribution to human lesions, she founded in 2009, the human immune monitoring center at Mount Sinaito implement technology platforms to maximize information obtained from limited biological samples. In 2016, she took the leadership of the Precision Immunology Institute at the icahn School of Medicine (PrIISM) to continue to lead initiatives to enhance human immunology science. PrIISM integrates immunological research programs across 42 laboratories with synergistic expertise in biology, medicine, technology, physics, mathematics and computational biology which come together to frame novel questions to understand the contribution of immune cells to disease initiation, progression and response to treatment, to implement cutting edge technologies andto develop novel immunotherapy strategies for the treatment of human diseases.   

Dr. Merad has authored more than 170 primary papers and reviews in high profile journals. She receives generous funding from the National Institutes of Health (NIH) for her research on innate immunity and their contribution to human disease, and belongs to several NIH consortia. In 2018, Dr. Merad received the prestigious William B. Coley Award for Distinguished Research in Tumor Immunology.   She is an elected member of the American Society of Clinical Investigation, and lectures around the world on her work. 

Please visit Dr. Merad's Lab website: http://icahn.mssm.edu/research/labs/merad-laboratory

Multi-Disciplinary Training Area

Immunology [IMM]

Education

MD, University of Algiers

Residency, University Paris VII (Interne des hopitaux de Paris)

MS (DEA), University Paris VII

PhD, Stanford University and University Paris VII

Postdoctoral Fellow, Stanford University