Navneet Dogra, PhD
- ASSISTANT PROFESSOR | Genetics and Genomic Sciences
- ASSISTANT PROFESSOR | Pathology, Molecular and Cell Based Medicine
Research Topics:Anti-Tumor Therapy, Biochemistry, Biomedical Informatics, Biomedical Sciences, Blood-Brain Barrier, Brain, Cancer, Cancer Genetics, Cell Biology, Clinical Genomics, Gene Discovery, Gene Expressions, Gene Therapy, Genetics, Genomics, Imaging, Membranes, Nanotechnology, Oncogenes, Parkinson's Disease, Pathology, Prostate, Protein Trafficking & Sorting, RNA, RNA Transport & Localization, Signal Transduction, Spectroscopy, Tissue Engineering, Trafficking, Tumor Suppressor Genes, Tumorigenesis, Viruses and Virology
Dr. Dogra's laboratory is working on the emerging field of genomics, liquid biopsy, and gene delivery, including: 1) Exosomes, Extracellular vesicles – nanoparticles actively secreted by cancer / tumor and benign tissue in human biofluids, 2) Cell-free DNA, RNA, and proteins – non-invasive tools for monitoring real time disease state, through RNA Sequencing, qRT-PCR, Proteomics etc., 3) Bioengineering – intersection of nanotechnology, microfluidics, drug delivery, and bioinformatics, and 4) Virus - Adeno-Associated Virus (AAV), SARS-CoV-2, COVID-19 genomics, drug discovery, and fundamental mechanism of endocytosis.
Prior to Mount Sinai, Dr. Dogra led research efforts at IBM research and Yale University to drive translational research in “liquid biopsy in cancer” and “drug delivery” by bridging together clinical and experimental oncology and develop novel tools for biosensing of genetic markers.
Dr. Dogra has recently filed for two US patents relating to “exosomes nanoparticles assisted drug delivery” and “tumor heterogeneity”. He has published in a diverse array of journals including Cell (research featured on the cover), Lab-on-a-chip, ACS Applied Materials and Interfaces (cover feature), ACS Bioconjugate Chemistry, Langmuir (cover feature), and Scientific Reports.
Dr. Dogra’s research has been featured in multiple media outlets including Yale News, NBC News, Yale Engineering Magazine, Science Daily, Futurity, R&D Magazine, Fox News, and Wall Street Journal...
2021 Best Oral Presentation, American Society for Intercellular Communication.
2021 Mount Sinai Alzheimer's Disease Research Center (ADRC) Scholar.
IBM “5 in 5” groundbreaking research award, Watson Research Center, NY
IBM Outstanding Technical Achievement Award, Watson Research Center, NY
Yale University Young Global Scholars Program, Falling Walls Finalist, New Haven, CT
Oak Ridge National Lab, TN, Summer Fellowship
Gower Research Fellow (Outstanding graduate student award), SIU, Carbondale IL
Dissertation research award, Southern Illinois University Carbondale, IL
Full list of publications :
Multi-Disciplinary Training AreasArtificial Intelligence and Emerging Technologies in Medicine [AIET], Cancer Biology [CAB], Genetics and Genomic Sciences [GGS], Neuroscience [NEU]
Bachelor's of Science, Himachal Pradesh University
Doctorate, Southern Illinois University Carbondale
Master's of Science, Guru Nanak Dev University
Post Doctoral Fellow, IBM Watson Research Center
Post Doctoral Fellow, Yale University
Mount Sinai Alzheimer's Disease Research Center (ADRC) Scholar.
Outstanding Technical Achievement Award
“5 in 5” groundbreaking research award
Yale Young Global Scholars Program, Falling Walls Finalist
Dissertation research award
Gower Research Fellow
Drug and Gene Delivery
Exosomes and other bio-nanoparticles for gene and drug delivery.
Exosomes and other Extracellular Vesicles
nanovesicles used for diagnostics, therapy, and bioengineering
Liquid-Biopsy in Cancer
Can we detect cancer biomarkers present in bodily fluids and avoid unnecessary surgical procedures? To answer this question, my research is focused on developing new liquid biopsy methods using circulating exosomes and extracellular vesicles, microfluidics, and next-gen genomic technologies.