
Saurabh Mehandru, MD
- PROFESSOR | Medicine, Gastroenterology
Specialties:
Gastroenterology, Internal MedicineResearch Topics:
AIDS/HIV, Aging, Antigen Presentation, Autoimmunity, B Cells, Cell Adhesion, Cell Biology, Cellular Immunity, Chemokines, Cytokines, Dendritic Cells, Epithelial Cells, Gene Expressions, Hepatitis C Virus, Immune Deficiency, Immunology, Immunosuppression, Infectious Disease, Inflammation, Integrins, Knockout Mice, Lung, Lymphocytes, Macrophage, Microarray, Mucosal Immunology, Retinoic Acid, Retrovirus, T Cells, TraffickingDr. Mehandru straddles the world of clinical care and laboratory based investigation. He graduated from the University College of Medical Sciences, Delhi University, India and then completed residency training in Internal Medicine at the NYU School of Medicine where he also served as Medical Chief Resident. He received subspecialty training in Clinical Gastroenterology at The Icahn School of Medicine at Mount Sinai.
Dr. Mehandru undertook post-doctoral training at the Rockefeller University, first working in the Laboratory of Dr. David Ho (with Dr. Martin Markowitz) and then in the Laboratory of Dr. Ralph Steinman, Nobel Laureate in Physiology or Medicine (2011).
During this period, Dr. Mehandru, reported on the preferential depletion of gut lymphocytes during acute HIV-1 infection and on the lack of immune reconstitution in the GI tract following years of apparently suppressive antiretroviral therapy.
After finishing his post-doctoral training, Dr. Mehandru was invited to join the faculty at Mount Sinai where in addition to serving as an Associate Professor of Gastroenterology, he leads a laboratory of Mucosal Immunology since 2013. Dr. Mehandru’s research interests include mucosal trafficking, the host-pathogen interface, dendritic cell biology and mucosal immunopathology in primary and acquired immunodeficiency states. He is an NIH-funded investigator who has received multiple awards.
Certifications
Gastroenterology
Clinical Focus
- Acid Reflux / Heartburn
- Angiodysplasia of the Colon
- Antibiotic-Associated Colitis-C Difficile
- Barrett's Esophagus
- Blood in Stool
- Celiac Disease
- Chronic Pancreatitis
- Colon Polyps
- Colorectal Cancer
- Constipation
- Crohn's Disease
- Diarrhea
- Dyspepsia
- Dysphagia
- Esophageal Cancer
- Familial Adenomatous Polyposis
- Gallstones
- Gastritis
- Gastroenterology
- Hemorrhoids
- Inflammatory Bowel Disease
- Iron-Deficiency Anemia
- Irritable Bowel Syndrome
- Jaundice
- Malabsorption
- Pancreatic Cancer
- Pancreatitis
- Peptic Ulcer
- Rectal Cancer
- Short Bowel Syndrome
- Stomach Cancer
- Stomach Pain
- Ulcerative Colitis
Multi-Disciplinary Training Area
Immunology [IMM]Education
MBBS, University of Damascus School of Medicine
Residency, Psychiatry, University of Delhi
Residency, Internal Medicine, Bellevue Hospital Center
Fellowship, Gastroenterology, Mount Sinai Hospital
Physicians and scientists on the faculty of the Icahn School of Medicine at Mount Sinai often interact with pharmaceutical, device and biotechnology companies to improve patient care, develop new therapies and achieve scientific breakthroughs. In order to promote an ethical and transparent environment for conducting research, providing clinical care and teaching, Mount Sinai requires that salaried faculty inform the School of their relationships with such companies.
Below are financial relationships with industry reported by Dr. Mehandru during 2022 and/or 2023. Please note that this information may differ from information posted on corporate sites due to timing or classification differences.
Consulting:
- Takeda Pharmaceuticals International GmbH; morphic
Mount Sinai's faculty policies relating to faculty collaboration with industry are posted on our website. Patients may wish to ask their physician about the activities they perform for companies.
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