About Us

The Translational and Molecular Imaging Institute (TMII). TMII focuses on the use of multimodality imaging for brain, heart, and cancer research, along with research in nanomedicine for precision imaging and drug delivery. TMII is composed of research groups in all aspects of imaging research, including:

  • Analytics
  • Basic Science
  • Chemistry
  • Computer Science
  • Engineering
  • Medicine
  • Physics

Located at the Leon and Norma Hess Center for Science and Medicine. At TMII, our team conducts cutting-edge research and accommodate the evolution of research platforms as new technologies emerge in the future.

Currently, the Translational and Molecular Imaging Institute has over 45 members with expertise in translational imaging research. TMII is currently staffed to support all the image acquisition, image analysis, scheduling, and performance of experiments.

TMII serves as a research catalyst for a new generation of translational and molecular imaging methodologies. TMII applies and validates imaging modalities, in both preclinical basic science and clinical research settings, to:

  • Improve diagnostic accuracy
  • Increase the understanding of disease mechanisms
  • Measure therapeutic efficacy
  • Offer education and training opportunities for students and postdoctoral research and clinical fellows
  • Provide comprehensive in-vivo imaging research service

Our mission is centered on development, validation, translation, and education of innovative technology in biomedical imaging. We aim to address both basic and clinical research problems to improve human health.  

To fulfill our mission, TMII combines state-of-the-art facilities with outstanding faculty, technical staff scientists, and administrative support staff.

Message from the Director

The primary goal of TMII which is to accelerate progress in translational "bench-to-bedside" research. Using high-performance systems, we are providing and assisting the research community’s access to and use of a comprehensive, state-of-the-art, and dynamic imaging infrastructure. Our comprehensive and integrated research structure focuses on using multimodality imaging for brain, cancer, and cardiovascular research. We also offer nanomedicine research to improve precision imaging and drug delivery.  

I invite you to learn more about TMII by exploring our website and researching the many achievements we have led and have been a part of. I look forward to a future of advancing scientific discoveries thanks to the wonderful faculty and staff at TMII.  

Zahi A Fayad, PhD
Director, TMII
To reach Dr. Fayad’s assistant, please contact Sybil Price.

Research

The first step to developing world-class treatments is a implementing exceptional diagnostic testing. Biomedical imaging now influences every step of research and clinical care. For example:

  • Brain imaging now allows us to look inside the brain without cutting it open. Human brain atlases that use brain mapping are being created to help us better understand the relationship between brain anatomy and function
  • Cancer detection with imaging has been shown to improve survival rates for lung and breast cancer
  • Cardiovascular disease is now diagnosed using coronary CT in the emergency room and has been proven to be a fast and effective way to select the most appropriate intervention for acute coronary patients
  • Nanomedicine has precision diagnostics and targeted drug delivery capabilities that have the potential to ensure drugs do not cause side effects or resistance. As a result, we can create therapies that include drugs to treat dangerous proteins. It is clear that innovative biomedical research requires frequent access to the newest and most advanced technologies

Among our most powerful equipment:

  • 7 Tesla ultra-high field MRI offers special resolution. This 39-Tone MR scanner allows us to detect early brain disease or cancerous tumors and assess them noninvasively at never-before-seen resolution and magnification. The scanner is almost twice as strong as the most commonly used MRI
  • Combination PET/MRI is used for heart, brain, and cancer imaging. This technology is a noninvasive, whole-body, dual-system that allows us to see within the arterial wall. The combo PET/MRI also enables investigators to develop novel methods for targeted imaging and drug delivery to improve the diagnosis and treatment of diseases
  • Dual Energy/Dual Source CT features two sets of x-ray tubes and detectors for enhanced imaging of all patients, including young children, patients with renal insufficiency, and those who cannot hold their breath. In cardiac imaging, it can obtain an entire study within one-quarter of a heart beat at a temporal resolution of 66 msec, which is the speed required to freeze the fastest-moving anatomy, such as the right coronary artery.