Jan 19, 2016
As a prescription drug, ketamine is an anesthetic, often used in veterinary medicine. It may also be a fast-acting treatment for depression. “Our experience with ketamine over the years is that it’s well-tolerated,” said psychiatrist and neuroscientist Dennis S. Charney, MD, Anne and Joel Ehrenkranz Dean of the Icahn School of Medicine at Mount Sinai. But not enough is known about how to maintain the drug’s antidepressant effects, perhaps through booster doses. “It’s still a work in progress,” Dr. Charney said.
Jan 18, 2016
A new treatment for psychiatric disorders like depression and anxiety uses real-time scans to show patients how their brains go awry—and how to fix the dysfunction. The treatment is called neurofeedback. Based on what their brains are doing, subjects are told to enhance or suppress that activity, says Anna Zilverstand, PhD, a postdoctoral researcher at the Icahn School of Medicine at Mount Sinai in New York and lead author of a 2015 study using neurofeedback to treat women with a phobia of spiders.
Jan 15, 2016
The MD Magazine Peer Exchange "Modifying the Course of Multiple Sclerosis in New Ways: The Latest Advances in Treatment" features a distinguished panel of physician experts discussing key topics in multiple sclerosis (MS) research and management, including the latest insights into MS pathophysiology, new medication options and their application in clinical practice, and more. The panel includes Fred D. Lublin, MD, director of The Corinne Goldsmith Dickinson Center for Multiple Sclerosis at The Mount Sinai Hospital.
Jan 17, 2016
Dan Iosifescu, MD, an associate professor of psychiatry and neuroscience at the Icahn School of Medicine at Mount Sinai, specializes in difficult-to-treat mood and anxiety disorders. Using magnets to induce activity in parts of the brain might sound like space-age medicine. But doctors are already using this futuristic technology to combat some types of depression. “Transcranial Magnetic Stimulation (TMS) is a non-invasive way of stimulating specific areas of the brain and, in the process of doing that, helping to correct or improve certain brain functions,” said Dr. Iosifescu.
Jan 11, 2016
Until recently, studies of people’s responses to such stress have focused primarily on men. Now, a growing number of scientists are studying what happens at the cellular and genetic levels in the brains of stressed-out rodents — male and female — to gain insight into the human brain. When the body’s alarm system remains on high alert for long periods, stress hormones can cause modifications to DNA, says Georgia Hodes, PhD, an assistant professor of neuroscience at the Icahn School of Medicine at Mount Sinai. Findings from Dr. Hodes’ study, published in the Dec. 16 Journal of Neuroscience, suggest that the removal of the molecule Dnmt3a increased the expression of genes that enabled malelike coping behaviors in the female rodents.
Jan 06, 2016
Unaffected siblings of individuals with bipolar disorder exhibited hyperconnectivity within the affect processing network, suggesting adaptive plasticity that allowed for compensatory changes, according to researchers. “The ability of the siblings to rewire their brain networks means they have adaptive neuroplasticity that may help them avoid the disease even though they still carry the genetic scar of bipolar disorder when they process emotional information,” said study researcher Sophia Frangou, MD, PhD, professor of psychiatry at the Icahn School of Medicine at Mount Sinai.
Dec 01, 2015
Stephen Nolan, a documentarian from Northern Ireland, spoke with several scientists around the United States about the effects of food on the human brain. He met with Nicole Avena, PhD, an assistant professor of pharmacology and systems therapeutics at the Icahn School of Medicine at Mount Sinai, to discuss food addiction. “When we overconsume sugar, it can activate these brain rewards systems that are associated with addiction,” said Dr. Avena. “It can release neurochemicals like dopamine and opioids.”
Nov 20, 2015
Stephen Krieger, MD, attending physician at the Corinne Goldsmith Dickinson Center for Multiple Sclerosis at The Mount Sinai Hospital and Associate Professor of Neurology at the Icahn School of Medicine, talks about temperature sensitivity in people with MS.
Nov 20, 2015
Paul Rinaldi, PhD, director of The Addiction Institute of New York at Mount Sinai West and Mount Sinai St. Luke’s, explains the dangers of adulterated versions of heroin.
Nov 11, 2015
A study by Stephan A. Mayer, MD, of the Icahn School of Medicine and colleagues is published in JAMA Neurology.
Nov 10, 2015
Dr. Rachel Yehuda, Professor of Psychiatry and Neuroscience and Director of the Traumatic Stress Studies Division at the Icahn School of Medicine, is quoted by U.S. News & World Report.
Nov 09, 2015
Stephan A. Mayer, M.D., of the Icahn School of Medicine and coauthors suggest loss of consciousness may be a predictor of death or poor functional outcome a year later.
Nov 04, 2015
Vanna Zachariou, MD, Associate Professor, and Houman Danesh, MD, Assistant Professor at the Icahn School of Medicine are interviewed by CBS local television in New York and discuss pain.
Nov 03, 2015
Georgia Hodes, PhD, a research track assistant professor in the Department of Neuroscience at the Icahn School of Medicine, discusses a new paper published in Nature.