The Friedman Brain Institute

Publications

Latest Publications

Calipari ES, Juarez B,, Morel C, Walker DM, Cahill ME, Ribeiro E, Roman-Ortiz C, Ramakrishnan C, Deisseroth K,Han MH, Nestler EJ. Dopaminergic dynamics underlying sex-specific cocaine reward. Nat Commun. 2017 Jan 10;8:13877. doi: 10.1038/ncomms13877

Morishita H, Arora M. Tooth-Matrix Biomarkers to Reconstruct Critical Periods of Brain Plasticity. Trends Neurosci. 2017 Jan;40(1):1-3. doi: 10.1016/j.tins.2016.11.003. Epub 2016 Dec 27

Elizabeth K. Lucas, Anita M. Jegarl, Hirofumi Morishita, Roger L. Clem. Multimodal and Site-Specific Plasticity of Amygdala Parvalbumin Interneurons after Fear Learning. Publication stage: In Press Corrected Proof, DOI

Golden SA, Heshmati M, Flanigan M, Christoffel DJ, Guise K, Pfau ML, Aleyasin H, Menard C, Zhang H, Hodes GE, Bregman D, Khibnik L, Tai J, Rebusi N, Krawitz B, Chaudhury D, Walsh JJ, Han MH, Shapiro ML, Russo SJ. Basal forebrain projections to the lateral habenula modulate aggression reward. Nature. 2016 Jun 29;534(7609):688-92. doi: 10.1038/nature18601.

Allyson K. Friedman, Barbara Juarez, Stacy M. Ku, Hongxing Zhang, Rhodora C. Calizo, Jessica J. Walsh, Dipesh Chaudhury, Song Zhang, Angel Hawkins, David M. Dietz, James W. Murrough, Maria Ribadeneira, Erik H. Wong, Rachael L. Neve & Ming-Hu Han. KCNQ channel openers reverse depressive symptoms via an active resilience mechanism. Nat Commun. 2016 May 24;7:11671. doi: 10.1038/ncomms11671.

Bagot RC, Cates HM, Purushothaman I, Lorsch ZS, Walker DM, Wang J, Huang X, Schlüter OM, Maze I, Peña CJ, Heller EA, Issler O, Wang M, Song WM, Stein JL, Liu X, Doyle MA, Scobie KN, Sun HS, Neve RL, Geschwind D, Dong Y, Shen L, Zhang B, Nestler EJ.Circuit-wide Transcriptional Profiling Reveals Brain Region-Specific Gene Networks Regulating Depression Susceptibility.Neuron. 2016 May 11. pii: S0896-6273(16)30074-5. doi: 10.1016/j.neuron.2016.04.015. [Epub ahead of print]

Zou H, Feng R, Huang Y, Tripodi J, Najfeld V, Tsankova NM, Jahanshahi M, Olson LE, Soriano P, Friedel RH. Double minute amplification of mutant PDGF receptor α in a mouse glioma model. Sci Rep. 2015 Feb 16;5:8468. doi: 10.1038/srep08468 

Readhead B, Haure-Mirande JV, Zhang B, Haroutunian V, Gandy S, Schadt EE, Dudley JT, Ehrlich ME. Molecular systems evaluation of oligomerogenic APPE693Q and fibrillogenic APPKM670/671NL/PSEN1Δexon9 mouse models identifies shared features with human Alzheimer's brain molecular pathology. Mol Psychiatry. 2015 Nov 10. doi: 10.1038/mp.2015.167. PMID:26552589

Junghyun Lim,  M. Lenard Lachenmayer, Wenchao Liu, Mondira Kundu, Rong Wang, Massaki Komatsu, Young J. Oh, Yanxiang Zhao and Zhenyu Yue    (2015)  Proteotoxic Stress Induces Phosphorylation of p62/SQSTM1 by ULK1 to Regulate Selective Autophagic Clearance of Protein Aggregates  PLoS Genetics  Feb 27;11(2):e1004987. doi: 10.1371/journal.pgen.1004987.

Tavares R, William C, Grossman Y, Mendelsohn A, Shapiro M, Trope Y, and Schiller D (2015) A map for social navigation in the human brain. Neuron 87, 231-243. 

Sun H, Damez-Werno DM, Scobie KN, Shao NY, Dias C, Rabkin J, Koo JW, Korb E, Bagot RC, Ahn FH, Cahill ME, Labonté B, Mouzon E, Heller EA, Cates H, Golden SA, Gleason K, Russo SJ, Andrews S, Neve R, Kennedy PJ, Maze I, Dietz DM, Allis CD, Turecki G, Varga-Weisz P, Tamminga C, Shen L, Nestler EJ. ACF chromatin-remodeling complex mediates stress-induced depressive-like behavior. Nat Med. 2015 Oct;21(10):1146-53. doi: 10.1038/nm.3939. Epub 2015 Sep 21.

Christoffel DJ, Walsh JJ, Golden SA, Heshmati M, Friedman AK, Dey A, Smith M, Rebusi N, Pfau M, Ables JL,Hodes GE, Deisseroth K, Ibanez-Tallon I, Han MH, Russo SJ.  Excitatory transmission at thalamo-striatal synapses mediates susceptibility to social stress. Nat Neurosci, 2015 Jul;18(7):962-4.

Haines JD, Herbin O, de la Hera B, Vidaurre OG, Moy GA, Sun Q, Fung HY, Albrecht S, Alexandropoulos K, McCauley D, Chook YM, Kuhlmann T, Kidd GJ, Shacham S, Casaccia P. Nuclear export inhibitors avert progression in preclinical models of inflammatory demyelination. Nat Neurosci. 2015 Apr;18(4):511-20. doi: 10.1038/nn.3953. Epub 2015 Feb 23.

Maze I, Wenderski W, Noh KM, Bagot RC, Tzavaras N, Purushothaman I, Elsässer SJ, Guo Y, Ionete C, Hurd YL, Tamminga CA, Halene T, Farrelly L, Soshnev AA, Wen D, Rafii S, Birtwistle MR, Akbarian S, Buchholz BA, Blitzer RD, Nestler EJ, Yuan ZF, Garcia BA, Shen L, Molina H, Allis CD. Critical Role of Histone Turnover in Neuronal Transcription and Plasticity. Neuron. 2015 Jul 1;87(1):77-94. doi: 10.1016/j.neuron.2015.06.014.

Fuertinger S1, Horwitz B2, Simonyan K3. The Functional Connectome of Speech Control. PLoS Biol. 2015 Jul 23;13(7):e1002209. doi: 10.1371/journal.pbio.1002209. eCollection 2015.

Hodes GE, Kana V, Menard C, Merad M, Russo SJ.  Neuroimmune mechanisms of depression. Nat Neurosci.

De Rubeis S1, Buxbaum JD2. Genetics and genomics of autism spectrum disorder: embracing complexity. Hum Mol Genet. 2015 Oct 15;24(R1):R24-31. doi: 10.1093/hmg/ddv273. Epub 2015 Jul 17.

Delvecchio G, Dima D, Frangou S. The effect of ANK3 bipolar-risk polymorphisms on the working memory circuitry differs between loci and according to risk-status for bipolar disorder. Am J Med Genet B Neuropsychiatr Genet. 2015; 168B(3):188-96.

Yehuda R, Daskalakis NP, Bierer LM, Bader HN, Klengel T, Holsboer F, Binder EB. Holocaust exposure induced intergenerational effects on FKBP5 methylation. Biological Psychiatry.

Browne HA, Hansen SN, Buxbaum JD, Gair SL, Nissen JB, Nikolajsen KH, Schendel DE, Reichenberg A, Parner ET, Grice DE. Familial clustering of tic disorders and obsessive-compulsive disorder. JAMA Psychiatry. 2015 Apr;72(4):359-66. doi: 10.1001/jamapsychiatry.2014.2656.

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