Common Gene Variants Account for Most Genetic Risk for Autism

 – July 21, 2014  –– 

A recent study has proved that 60 percent of the risk for developing autism is caused by genetics and a major portion of that risk is caused by inherited variant genes that are common in the population and present in individuals without the disorder. Joseph D. Buxbaum, MD, Director of the Seaver Autism Center for Research and Treatment and Professor of Psychiatry, Neuroscience and Genetics and Genomic Sciences at the Icahn School of Medicine at Mount Sinai, said that they have shown very clearly that inherited common variants comprise the bulk of the risk that sets up susceptibility to autism and while there are families that can be genetically loaded for autism risk, additional rare genetic factors are required to actually produce the disorder in a particular family member.

-Dr. Josepsh Buxbaum, Professor Psychiatry, Neuroscience, Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai.

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