Wall Street Journal - "Fighting Parkinson's Drug Side Effects" - Shirley S. Wang

New York, NY
 – March 25, 2013  –– 

Inhibiting A2a receptors could counteract some of the side effects of levodopa, according to Dr. C. Warren Olanow, a neurology professor at The Mount Sinai Hospital. In a mid-stage clinical trial, tozadenant, being developed by Biotie and UCB, Inc., demonstrated a one-hour reduction in off-time for patients who received the optimal dose compared with placebo. That's close to drugs already on the market, says Dr. Olanow, an investigator on a trial who presented findings last week at the annual meeting of the American Academy of Neurology in San Diego.

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