Mount Sinai Program in Normal and Malignant Hematopoiesis Research 

Hematopoiesis Research at Mount Sinai 

The Icahn School of Medicine has a long tradition of excellence in hematology research and training. Numerous pioneering investigations have been performed here and the institution has a long track record of trainees who have assumed academic positions at institutions throughout the world. Our current faculty continue to pursue this outstanding tradition not only in the Division of Hematology and Medical Oncology but also in the departments of Developmental and Regenerative Biology, Gene and Cell Medicine, Immunobiology and Pediatrics. Faculty engaged in hematopoiesis research are members of the Tisch Cancer Institute, the Black Family Stem Cell Institute, the Immunology Institute, and the Institute for Child Health and Development. Over the past decade, Mount Sinai has seen an enormous expansion of its research portfolio and the number of faculty. 

Postdoctoral Training in Normal and Malignant Hematopoiesis at Mount Sinai 

Full-time postdoctoral training in the Mount Sinai Research Program in Normal and Malignant Hematopoiesis provides the opportunity for recent doctoral degree recipients to enhance their research skills in the resource-rich, collaborative environment of the Icahn School of Medicine. 

Trainees accepted into the program may choose to work with any of the associated faculty, in areas ranging from the study of hematopoietic stem cells to hematologic malignancies: 

• Julio A. Aguirre-Ghiso, PhD, Associate Professor. Therapy-induced dormancy in multiple myeloma.
• Margaret H. Baron, MD PhD, Professor. Hematopoietic development in health and disease.
• James Bieker, PhD, Professor. Transcriptional control of erythropoiesis.
• Steven Burakoff, MD, Professor. T cell activation and function.
• Barry Coller, MD, Clinical Professor (Mount Sinai) and Head, Laboratory of Blood and Vascular Biology, The Rockefeller University. Platelet physiology in health and disease.
• Bruce Gelb, MD, Professor. Ras-associated myeloid disorders.
• Saghi Ghaffari, MD, PhD, Associate Professor. Hematopoietic and leukemic stem cell development.
• Ronald Hoffman, PhD, Professor. Myeloproliferative disorders.
• Yongkui Jing, PhD, Associate Professor. Targeted therapy of leukemia.
• Ihor Lemischka, PhD, Professor. Stem cell pluripotency.
• Miriam Merad, MD PhD, Professor. Dendritic cells in health and disease.
• Anna-Rita Migliaccio, PhD, Professor. Normal and pathological erythropoiesis and megakaryopoiesis.
• Kateri Moore, DVM, Associate Professor. Hematopoietic stem cell niche.
• Lewis Silverman, MD, Associate Professor. Myelodysplastic syndromes.
• Hans Snoeck, MD PhD, Associate Professor. Hematopoietic stem cell biology. 

Eligibility
• To be eligible for support from this training program, applicants must hold a doctoral degree (PhD, MD, or equivalent).
• Trainees may also be eligible for an appointment to our National Institutes of Health-funded Training Program in Hematology Research (NIH T32 HL094283; Program Director, Margaret H. Baron, MD PhD), for up to 3 years of support. These trainees must be a U.S. citizen or permanent resident. Appointments are made on a competitive basis. 

Stipend and Benefits
Stipends for postdoctoral trainees are adjusted yearly, and may include supplements for prior experience and multiple degrees. Benefits include health insurance for the trainee and his/her family. Support for coursework related to the trainee's research and travel to meetings may be available. 

How to Apply
Applications will be evaluated on a rolling basis. To apply, please send the following information to hemeresearch@mssm.edu 

1. cover letter
2. curriculum vitae
3. names and contact information for 3 references

Red EKLF and green SUMO overlap (yellow) in blue nuclei (top), but mutant EKLF does not (bottom). (Image supplied by James Bieker.)

Expression of a nuclear GFP reporter targeted to EryP in e-globin::H2B-GFP transgenic mouse embryos. The nuclear GFP coats the chromosomes and can be visualized in all phases of the cell cycle, including mitosis (far right). (Image supplied by Margaret Baron.)

Langerhans cells accumulating in the hair follicle. (Image supplied by Miriam Merad).

Giemsa stained cytospin of myeloid cells derived from Noonan syndrome iPS cells. (Image supplied by Bruce Gelb.)