The Department of Obstetrics, Gynecology, and Reproductive Science is dedicated to patient-oriented research. We combine scholarship with new clinical treatments to provide the best possible outcomes for our patients. From new approaches in cancer prevention and diagnosis to clinical trials, our research is designed to dramatically improve the lives of our patients and women worldwide.

Residents are required to complete an original research project during their third year of training. All our fellowships include dedicated research time in the curriculum as outlined by accreditation agencies.

Scientific Highlights

Since our inception in 1877, our Department has been expanding women’s health care through innovative research and clinical care. Our departmental highlights include:

  • Determining that the efficiency of in vitro fertilization (IVF) could be greatly increased if the sperm were assisted in reaching the surface of the egg
  • Recognizing the link between estrogen replacement therapy and endometrial cancer (led by Saul Gusberg, MD)
  • Introducing platinum chemotherapy for the treatment of ovarian cancer (led by Carmel J.Cohen, MD)
  • Developing chorionic villus sampling as a routine genetic screening test (led by Richard L. Berkowitz, MD,  James D. Goldberg, MD, and Robert J. Desnick, MD, PhD)
  • Demonstrating fetal-fibronectin as a marker for premature delivery (led by Charles J. Lockwood, MD)
  • Advancing minimally invasive techniques for the surgical management of gynecologic disease (led by Farr Nezhat, MD, Peter Dottino, MD, and Jamal Rahaman, MD)

Current Research Initiatives

Obstetrics, Gynecology, and Reproductive Science trainees work alongside our physician-researchers to supplement their clinical training. Current research initiatives range from maternal fetal medicine studies to cancer clinical trials. Our investigators are also closely linked with the Department of Population Health Science and Policy and conduct population health studies in maternal and child health. These include:

  • Women's Health Research Institute to optimize quality of care for women across the life span and to narrow gaps in treatment and outcomes in underserved populations
  • A five-year grant from the National Institutes of Health (NIH) to study each trimester of pregnancy and each trimester’s unique hormonal environments
  • An NIH-funded grant to investigate quality of care and severe maternal morbidity and mortality 
  • An NIH-funded grant to investigate racial and ethnic disparities in infant mortality
  • Trials assessing the safe use of antiretroviral treatments for the prevention of mother-to-child HIV transmission
  • Clinical trials for women with ovarian, uterine (endometrial), and cervical cancers
  • Studies comparing different chemotherapy agents in various staged uterine and ovarian cancer—as well as preoperative imaging for cervical cancers
  • Partnerships with drug companies on international clinical trials to develop new vaccines
  • A Robert Wood Johnson Foundation study to improve postpartum women’s health
  • Studies examining an association between social policy and rates of preterm births