As an MD/PhD student at the Icahn School of Medicine at Mount Sinai (ISMSS), you will have many opportunities to be a part of the cutting-edge research taking place in some of our nation’s best laboratories.

We are committed to training strong researchers. Our Hess Center for Science and Medicine recently added 550,000 square feet of laboratory and clinical space for further collaborations among our extensive research and physician community. Our students have been published in Proceedings of the National Academy of Sciences, Journal of Clinical Investigation, Molecular Cell, Nature, and more.

Below are some of our standout student publications from 2014.

Chong RA, Wu K, Spratt DE, Yang Y, Lee C, Nayak J, Xu M, Elkholi R, Tappin I, Li J, Hurwitz J, Brown BD, Chipuk JE, Chen ZJ, Sanchez R, Shaw GS, Huang L, Pan ZQ (2014) Pivotal role for the ubiquitin Y59-E51 loop in lysine 48 polyubiquitination. Proc Natl Acad Sci U S A 111:8434-8439.

Cook JR, Carta L, Bénard L, Chemaly ER, Chiu E, Rao SK, Hampton TG, Yurchenco P; GenTAC Registry Consortium, Costa KD, Hajjar RJ, Ramirez F (2014) Abnormal muscle mechanosignaling triggers cardiomyopathy in mice with Marfan syndrome. J Clin Invest 124:1329-1339.

Cummins MA, Dalal PJ, Bugana M, Severi S, Sobie EA (2014) Comprehensive analyses of ventricular myocyte models identify targets exhibiting favorable rate dependence. PLoS Comput Biol 10:e1003543.

Dias C, Feng J, Sun HS, Shao NY, Mazei-Robison MS, Damez-Werno D, Scobie K, Bagot R, Labonte B, Ribeiro E, Liu ZC, Kennedy P, Vialou V, Ferguson D, Peña C, Calipari E, Koo JW, Mouzon E, Ghose S, Tamminga C, Neve R, Shen L, Nestler EJ (2014) ß-Catenin mediates stress resilience through Dicer1/microRNA regulation. Nature 516:51-55.

Gingold JA, Fidalgo M, Guallar D, Lau Z, Sun Z, Zhou H, Faiola F, Huang X, Lee DF, Waghray A, Schaniel C, Felsenfeld DP, Lemischka IR, Wang J (2014) A genome-wide RNAi screen identifies opposing functions of Snai1 and Snai2 on the Nanog dependency in reprogramming. Mol Cell 56:140-152.

Goff PH, Hayashi T, Martínez-Gil L, Corr M, Crain B, Shiyin Yao, Cottam HB, Chan M, Ramos I, Eggink, D, Heshmati M, Krammer F, Messer K, Pu M, Fernandez-Sesma A, Palese P, Carson DA (2014) Synthetic TLR4 and TLR7 ligands as influenza virus vaccine adjuvants induce rapid, sustained and broadly protective responses. J Virol, in press.

Huynh JL, Garg P, Thin TH, Yoo S, Dutta R, Trapp BD, Haroutunian V, Zhu J, Donovan MJ, Sharp AJ, Casaccia P (2014) Epigenome-wide differences in pathology-free regions of multiple sclerosis-affected brains. Nat Neurosci 17:121-130.

Israelow B, Mullokandov G, Agudo J, Sourisseau M, Bashir A, Maldonado AY, Dar AC, Brown BD, Evans MJ (2014) Hepatitis C virus genetics affects miR-122 requirements and response to miR-122 inhibitors. Nat Commun 5:5408.

Jacob V,  Chernyavskaya Y, Chen X, Tan PS, Kent B, Hoshida Y, Sadler KC (2014) DNA hypomethylation induces a DNA replication-associated cell cycle arrest to block hepatic outgrowth in uhrf1 mutant zebrafish embryos. Development, in press.

Lavin Y, Winter D, Blecher-Gonen R, David E, Keren-Shaul H, Merad M, Jung S, Amit I (2014) Tissue-resident macrophage enhancer landscapes are shaped by the local microenvironment. Cell 159:1312-26.

Vasudevan HN, Soriano P (2014) SRF regulates craniofacial development through selective recruitment of MRTF cofactors by PDGF signaling. Developmental Cell 31:332-344.

Wohlbold TJ, Krammer F (2014) In the shadow of hemagglutinin: a growing interest in influenza viral neuraminidase and its role as a vaccine antigen. Viruses 6:2465-2494.