Biorepository and Pathology

Through the Biorepository and Pathology CoRE we provide basic histology services including the capability to process, embed, and section fixed and frozen tissues (both animal and human) for the Mount Sinai Health System and the external academic and biopharmaceutical community.

Our facility can also generate tissue microarrays utilizing materials directly from the biorepository, animal model systems or in coordination with the clinical pathology service. We will prepare unstained slides suitable for a variety of applications such as histochemistry, immunohistochemistry, immunofluorescence, in situ hybridization, laser capture microdissection, as well as hematoxylin and eosin and other special stains for routine light microscopic evaluation. We also support DNA/RNA/miRNA extraction from fluids and tissue specimens (both fixed and frozen) and we have a digital scanning and image analysis service.

The Biorepository currently supports functions for tissue/body fluid procurement, storage and tracking from consented and de-identified collections. Pathologists responsible for procurement can be contacted for consultation to determine investigator requirements for human specimens in translational research, and then arrange procurement as feasible.

Introducing our first web-based, easy to use, Biorepository search tool!

Investigators will now have an opportunity to query the biobank in real-time; ultimately being able to utilize biospecimens for their translational research projects.

Please follow the instructions carefully:

  • When the web-based interface is launched you must first select the Disease Group of interest which automatically populates the appropriate 'Anatomical Location' drop-down menu.
  • Features such as race are not always available when specimens are collected.  We recommend performing a more general search which may include age and diagnosis.  This should be followed by a comprehensive review of the generated specimen list.
  • Once specific samples have been selected click on the 'Requested Selected Specimens' button.  An email will automatically be sent to the appropriate disease group utilization committee for review and follow-up.  The biorepository personnel will also be notified.  All requests will be answered within two - three days.

    Please email questions regarding the use of the web-based tool to Javier.Martin-Fernandez@mssm.edu.

In order to sustain the Biorepository for current and future investigator’s it is critically important that you acknowledge the Biorepository and Pathology CoRE in all publications, grants, and awards that include any data or services you have derived from our facility. This is a mandatory requirement for funding.

The Biorepository and Pathology CoRE has been providing services to the Mount Sinai Health System research community as well as external investigators since 2006, facilitating high quality translational research, multiple collaborative studies, and numerous peer-reviewed publications.

Please let us know whenever any publication or grant has evolved as a result of involving any of the services of the Biorepository and Pathology CoRE.