Biorepository and Pathology CORE
The Biorepository and Pathology CORE provides basic histology services including the capability to process, embed and section fixed and frozen tissues (both animal and human) for Mount Sinai and the external academic and biopharmaceutical community. The facility is also able to generate tissue microarrays (TMAs) utilizing materials directly from the biorepository, animal model systems or in coordination with the clinical pathology service. The facility will prepare unstained slides suitable for a variety of applications such as histochemistry, immunohistochemistry (IHC), immunofluorescence (IF), in situ hybridization (ISH), Laser capture microdissection (LMD), as well as hematoxylin and eosin (H&E) and other special stains for routine light microscopic evaluation. We also support DNA/RNA/miRNA extraction from fluids and tissue specimens (both fixed and frozen) and we have a digital scanning and image analysis service.
The Biorepository currently supports functions for tissue/body fluid procurement, storage and tracking from consented and de-identified collections. Pathologists responsible for procurement can be contacted for consultation to determine investigator requirements for human specimens in translational research, and then arrange procurement as feasible.
Please Remember – It is important to acknowledge the Biorepository and Pathology CORE in all publications that include data derived from the facility.
Please contact us for consultation:
Annenberg Building, Room 15-56
1468 Madison Avenue
New York, NY 10029
Michael J. Donovan, MD, PhD
Mireia Castillo-Martin, MD, PhD