The Apheresis Center

By providing therapeutic apheresis (TA) and peripheral blood stem cell (PBSC) collection services at the Mount Sinai Health System, the Apheresis Center is helping clinical teams treat patients and save lives every day.

Our Apheresis Center supports a number of highly active clinical services and programs at Mount Sinai, including Hematology/Oncology, Neurology, Bone Marrow/Hematopoietic Stem Cell Transplant, Solid Organ Transplantation (such as for heart, kidney), Nephrology, and Rheumatology.

Our Center is staffed with skilled apheresis physicians and nurses committed to providing the highest quality patient care. Quality Assurance programs have been implemented to ensure compliance with regulatory and accreditation requirements, including those of the U.S. Food and Drug Administration, the New York State Department of Health, The Joint Commission, the Foundation for the Accreditation of Cellular Therapy, the American Society for Apheresis, the Association of Advancing Transfusion and Cellular Therapies Worldwide, and the College of American Pathologists.

The Apheresis Center performs the following types of therapies. We also provide medical consultations.

The theoretical basis for TA is to reduce the patient’s load of a pathologic substance to levels that will allow clinical improvement. We sometimes perform TA  rmed to replace a substance that is normally present in blood, but absent or dysfunctional in a particular patient. Our lab conducts therapies that include the following:

  • Plasmapheresis: Therapeutic plasma exchange is indicated for a number of diseases and conditions in areas such as Hematology/Oncology, Neurology, Solid Organ transplant rejections, Nephrology, Rheumatology, and Hepatic Diseases.
  • Leukapheresis: Therapeutic white cell depletion has been used to treat dramatically elevated white cell counts that can occur in acute leukemia.
  • Erythrocytapheresis: Therapeutic red cell exchange can be used to treat complications of Sickle Cell Disease.
  • Plateletpheresis: Therapeutic platelet depletion can be used for thrombocytosis (such as thrombocythemia) in symptomatic patients with platelet counts above 1,000,000/uL.
  • Photopheresis: Photopheresis (white cells exposed to ultraviolet light) can be used to treat cutaneous T-cell lymphoma and graft-versus-host disease 
  • Peripheral Blood Stem Cell (PBSC): PBSC collection is the extraction of stem cells from peripheral blood (as opposed to bone marrow) for potential use in hematopoietic stem cell transplantation.

We are participating in a clinical study (Baylor Dendritic Cell 08-0906), which utilizes dendritic cells as novel therapeutic vaccines in cancer. 

Investigators for cellular therapy are encouraged to contact Ding Wen Wu, MD, PhD, Associate Director of Transfusion Medicine/Cellular Therapy, during the grant-writing process to seek advice on the most appropriate cellular component collection protocols.

The Apheresis Center’s physicians and nurses are passionate, skilled, and specially trained professionals. All members of our apheresis team meet the regulatory and accrediting requirements. 

Apheresis Physicians
Kathleen Leonard, MD

Yoon Choo, MD
Associate Director 

Ding Wen Wu, MD, PhD
Associate Director 

Ahperesis Nurses
Emeris Nash, RN (Nurse in charge) 

Godsfavour Guillet, RN (Nurse Manager) 

Glenda Adriano, RN 

Felmina Ajero, RN 

Lagarde, Ebben, RN 

Lee, Eunju, RN