Basic Research Training
Cardiovascular Research Initiatives Within the Mount Sinai Cardiovascular Research Institute and Mount Sinai Heart
Recognizing that the future of basic cardiovascular research is in molecular approaches, Mount Sinai has made a major commitment towards developing one of the premier programs in the country. Established scientists in specific programs and centers perform cutting edge research illuminating cardiovascular biology and disease and train clinicians and scientists to become future leaders of these fields.
The Cardiovascular Research Institute provides a home for a wide spectrum of investigation ranging from the most basic science to disease-focused and patient-based research. It also links faculty interested in cardiovascular biology and disease across Mount Sinai programs, departments, and campuses. The diversity of the faculty and its collaborative culture fosters a multidisciplinary approach to research problems and provides an important bridge between Mount Sinai's outstanding clinical and basic science departments.
The research programs in Molecular and Cellular Cardiology have received substantial funding from the NIH, AHA and ACC. There are myriad opportunities for cardiology fellows to pursue basic and translational research. Fellows participating in the program have been involved in major research efforts in the areas of atherosclerosis, heart failure, transplant biology, cardiac excitation, ion channels, cardiomyopathy, and thrombosis. Fellows take courses in Molecular Biology, Cell Biology, Signal Transduction, Physiology and Neurobiology offered through the Graduate School Faculty of Mount Sinai. Fellows participate in journal clubs and seminars offered by the Brookdale Molecular Biology Center and the Molecular Medicine Program. Typically, fellows have presented the results of their work at the most prestigious international meetings of the American Heart Association, American College of Cardiology and American Federation for Medical Research (formerly AFCR).
The Cardiovascular Research Center at Mount Sinai is directed by Dr. Roger J. Hajjar and contains more than 10,000 square feet of newly renovated laboratory space on the 3rd and 5th floors of the Atran Building. The Center is comprised of investigators and physician-scientists teamed with over 50 highly-trained staff and engaged trainees. The Center's central mission is to focus on molecular mechanisms of human cardiovascular disease; translation of basic findings to novel therapies and diagnostics; and the mentoring of MD and PhD trainees committed to careers in academic cardiovascular research.
The Molecular Cardiology Research Center is organized into laboratories that focus on several key areas of cardiovascular research (some of which are elaborated under Featured Research):
- Stem Cell Biology
- Heart Failure & Cardiomyocyte Biology
- Signal Transduction
- Vascular Biology
- Inflammation & Cardiovascular Disease
- Molecular Imaging