Key programs of ConduITS – the Institutes for Translational Sciences include:
Administration Core (Office of Research Services)
The Office of Research Services (ORS) is a central resource for the Mount Sinai Health System (MSHS) research community by providing innovative tools, services and consultations. The ORS innovative research tools include 1) liaison between ConduITS and National CTSA Network of hubs; 2) Research 411 Help Desk as single point of contact for research teams to ask any research operations related questions and access assistance with the consultative services that the ORS offers; 3) the Research Roadmap (RRM) is a centralized, dynamic, interactive web-based tool being optimized by the ORS to assist research teams in navigating the methods and processes of the MSHS research infrastructure and study lifecycles; and 4) the Clinical Trials Management System (CTMS), 5) OnCore, will impact rapid activation of clinical trials by enhanced protocol and informed consent life cycle management improving IRB approval duration and continuing renewal.
Informatics Core
Informatics is increasingly driving research that informs precision medicine, population health, and biomedical big data science. Mount Sinai’s ConduITS' success in catalyzing computational and data science resources and expertise in basic, translational and clinical science. Through our Scientific Computing and Data partners and Research Information Technology department we can meet your information technology needs through every step of the research process.
Community & Collaboration Core
Collaboration and community are crucial components of highly productive research ecosystems that advance human health. Modern translational research addresses these advances while remaining grounded in the community and patient advocacy. ConduITS has built upon the infrastructure supporting our Community Engagement and Team Science programs. These programs will transform the clinical translational research landscape resulting in changes that benefit health systems and neighborhoods in New York City and beyond.
Translational Endeavors Core
ConduITS’s Translational Endeavors (TE) will build upon a foundation of multidisciplinary and interdisciplinary educational undertakings in clinical and translational science (CTS) to advance an evolved framework for transdisciplinary (TD) training and research. Our TE will 1) provide graduate and postgraduate research training programs through the Translational Workforce Development; 2) for further development of leadership skills our Leadership Emerging in Academic Departments Program (LEAD) includes modules in communication, negotiation, inspiring trust and embracing diversity; and 3) Mini-Sabbaticals for researchers to attend short courses in order to acquire added competencies in specific areas of translational research. Moreover, for further in research education and career development please see the ConduITS page Education and Career Development.
Research Methods Core
The Research Methods Core works seamlessly with other cores of ConduITS, the Mount Sinai Health System (MSHS) CTSA to leverage and maximize the use of existing resources and to collaboratively build new ones while avoiding redundancies. Through 1) Biostatistics, Epidemiology & Research Design (BERD) we enhance the productivity of all investigators by providing expert biostatistical and data science support. To access BERD assistance, please see the Resources section within our For Investigators page; and 2) the Regulatory Knowledge and Support (RKS) provides a central portal for the integration and facilitation of CTR regulatory education, guidance, services and e-tools for CTR teams. The Recruitment and Retention of Research Participants is a challenge often faced in clinical research---it is important that recruitment and retention is considered early on during budget development and negotiation. Moreover, the Research 411 Help Desk is available to assist and support investigators with research operations related questions and access assistance with the consultative services and regulatory support.
Hub Research Core
The Hub Research Capacity Core is dedicated to build critical components for an effective and efficient clinical translational research enterprise. The International Center for Health Outcomes and Innovation Research (InCHOIR) is a clinical and data coordinating center with faculties who are experts in study design, clinical coordination, regulatory approval and management, endpoint and event adjudication and Data Safety and Monitoring Board management.
Network Capacity Core
The Network Capacity Core provides oversight for the interactions between Mount Sinai hub activities as well as network resources of the national CTSA program. The Trial Innovation Network (TIN) seeks to address critical roadblocks in clinical trials and accelerate the translation of novel research into clinical practice.
Exposomics Core
Mount Sinai has positioned itself as a world leader in exposomics with the world’s first Institute for Exposomic Research, which houses the Lautenberg Exposomics Laboratory and our Center for Geomedicine. We have chosen Exposomics, which applies systems biology, informatics, computation tools, omic technologies and the methodologies of environmental exposure assessment, as an area to focus our efforts, given our unique scientific strengths in this compelling new area of translational science.
Innovation Core
Entrepreneurship in the healthcare sector has become increasingly important. Mount Sinai’s Innovation Partners (MSIP) is responsible for driving the real-world application and commercialization of Mount Sinai discoveries and inventions, and the development of research partnerships with industry. MSIP integrates the academic vision and resources of ConduITS and the Mount Sinai CTSA to translate discoveries and inventions into health care products and services that benefit patients and society.
TL1 Core
The TL1 Core develops, implements and disseminates innovative educational pipeline programs in transdisciplinary (TD) clinical and translational science (CTS). Our programs will catalyze the development of the next generation of leaders in CTS and TD research through the 1) Patient Oriented Research Training and Leadership Program (PORTAL), a dual degree (MD/MSCR) degree program that you may be eligible for if you are experienced in the clinical research environment and want to create a foundation for a career in translational research; and 2) the Sinai Team-based Translational Education Program: the URM Propeller Initiative in Science and Medicine (STTEP-UP) motivates URM trainees in residency, subspecialty fellowship training or postdoctoral laboratory positions within our health care system, to become innovative leaders and entrepreneurs in clinical and translational research.
KL2 Core
The KL2 Core or Center for Patient Oriented Research, Training, Education, and Development (CePORTED) goal is to develop a cohort of transdisciplinary (TD) scientists who have the skills necessary to navigate the critical future issues of health and disease in our increasingly complex world. The KL2 Scholars Award for Clinical and Translational Research Career Development will be trained in core competencies including epidemiology, study design, biostatistics/data science, informatics, clinical trials, and ethical/regulatory guidelines, as well as have broad exposure to the methodological steps of the translational process from discovery to community engagement via innovation, life course research, and workforce development.