Transplant Infectious Diseases Program

The Mount Sinai Transplant Infectious Diseases Program is dedicated to the prevention and management of infectious diseases in solid organ and stem cell transplant recipients as well as other immunocompromised hosts. With a collaborative clinical and academic relationship with the Heart Transplant Program, the Recanati-Miller Transplant Institute and the Bone Marrow Transplant Program, our program is dedicated to providing the following services:

  • Collaboration with each individual transplant program to provide excellent clinical care in both the inpatient and outpatient setting
  • Educational support for each individual transplant program to ensure that the clinical practices meet the standard of care
  • Expertise to develop guidelines for the prevention and management of infections for each individual transplant program
  • Innovative research initiatives that advance the field and improve the care of our patients

Patient Care

  • The Organ Transplant Infectious Diseases Consult Service and the BMT/Oncology Infectious Diseases Consult Service are each staffed by one faculty member and one infectious diseases fellow at all times and provide inpatient consultation and follow-up for all patients with suspected or confirmed infections. The Organ Transplant ID Service sees patients on the following services: liver medicine, liver transplant, kidney-pancreas transplant, intestinal transplant, mechanical circulatory support, and heart transplant. The BMT/Oncology ID Service sees patients on all oncology services.
  • The Transplant Infectious Diseases Outpatient Practice performs pre-transplant evaluations, consultations, and follow-ups for all patients before and after transplantation.

Education

  • The program is essential to the training of the Mount Sinai Infectious Diseases Fellows who rotate on the consult services during the first year of fellowship and may also participate in a Transplant Track during the second year of fellowship.
  • Additionally, fellows from the greater New York City area participate in the Mount Sinai Transplant Infectious Diseases Visiting Fellow Program to receive training in the care of transplant recipients and other immunocompromised hosts.

Research

The program is also dedicated to a research program with active or upcoming projects in the following areas

  • Epidemiology, prevention and treatment of resistant Gram-negative infections
  • Solid organ transplantation in HIV-infected patients
  • Prevention of CMV following solid organ transplantation

Shirish Huprikar, MD
Professor, Medicine/Infectious Diseases 

Meena Rana, MD
Assistant Professor, Medicine/Infectious Diseases 

Tim Sullivan, MD
Assistant Professor, Medicine/Infectious Diseases

Sarah Taimur, MD
Assistant Professor, Medicine/Infectious Diseases

Dallas Dunn, MD
Assistant Professor, Medicine/Infectious Diseases

Kalpoe JS, Sonnenberg E, Factor SH, del Rio Martin J, Schiano T, Patel G, Huprikar S. Mortality associated with carbapenem-resistant Klebsiella pneumoniae infections in liver transplant recipients.Liver Transpl. 2012 Apr;18(4):468-74.

Rana MM, Sturdevant M, Patel G, Huprikar S. Klebsiella necrotizing soft tissue infections in liver transplant recipients: a case series. Transpl Infect Dis. 2013 Aug;15(4):E157-63.

Huprikar S, Bosserman E, Patel G, Moore A, Pinney S, Anyanwu A, Neofytos D, Ketterer D, Striker R, Silveira F, Qvarnstrom Y, Steurer F, Herwaldt B, Montgomery S. Donor-derived Trypanosoma cruzi infection in solid organ recipients in the United States, 2001-2011. Am J Transplant. 2013 Sep;13(9):2418-25.

Reid G, Huprikar S, Patel G, Razonable RR, Mossad S, Levi M, Gregg K, Shoham S, Humar A, Adams W, Kumar D.A multicenter evaluation of pandemic influenza A/H1N1 in hematopoietic stem cell transplant recipients. Transpl Infect Dis. 2013 Oct;15(5):487-92.

Swartz TH, Huprikar S, Labombardi V, Pinney S, Anyanwu A, Lee M, Patel G. Heart transplantation in a patient with heteroresistant vancomycin-intermediate Staphylococcus aureus ventricular assist device mediastinitis and bacteremia. Transpl Infect Dis. 2013 Oct;15(5):E177-81.

Assi M, Martin S, Wheat LJ, Hage C, Freifeld A, Avery R, Baddley JW, Vergidis P, Miller R, Andes D, Young JA, Hammoud K, Huprikar S, et al. Histoplasmosis after solid organ transplant. Clin Infect Dis. 2013 Dec;57(11):1542-9.

Madan RP, Carpini KD, Huprikar S, Lerner H, Patel G, Ratner LE, Goldstein MJ, Herold BC on behalf of the New York Organ Donor Network Infectious Disease Working Group. A Pilot Program to Evaluate Deceased Donor Disease Transmission Risk: The New York Organ Donor Network Infectious Disease Working Group.Transplantation. 2014 May 29. [Epub ahead of print]

Sullivan T, Brodginski A, Patel G, Huprikar S. The Role of Secondary Cytomegalovirus Prophylaxis for Kidney and Liver Transplant Recipients.Transplantation. 2014 Sep 9. [Epub ahead of print]

Altman DR, Sebra R, Hand J, Attie O, Deikus G, Carpini KW, Patel G, Rana M, Arvelakis A, Grewal P, Dutta J, Rose H, Shopsin B, Daefler S, Schadt E, Kasarskis A, van Bakel H, Bashir A, Huprikar S.Transmission of methicillin-resistant Staphylococcus aureus via deceased donor liver transplantation confirmed by whole genome sequencing. Am J Transplant. 2014 Nov;14(11):2640-4.

Sun HY, Alexander BD, Huprikar S, Forrest GN, Bruno D, Lyon GM, Wray D, Johnson LB, Sifri CD, Razonable RR, Morris MI, Stosor V, Wagener MM, Singh N. Predictors of immune reconstitution syndrome in organ transplant recipients with cryptococcosis: implications for the management of immunosuppression. Clin Infect Dis. 2015 Jan 1;60(1):36-44.

Abanyie FA, Gray EB, Delli Carpini KW, Yanofsky A, McAuliffe I, Rana M, Chin-Hong PV, Barone CN, Davis JL, Montgomery SP, Huprikar S. Donor-Derived Strongyloides stercoralis Infection in Solid Organ Transplant Recipients in the United States, 2009-2013. Am J Transplant. 2015 Feb 20. doi: 10.1111/ajt.13137. [Epub ahead of print]

Huprikar S, Danziger-Isakov L, Ahn J, Naugler S, Blumberg E, Avery RK, Koval C, Lease ED, Pillai A, Doucette KE, Levitsky J, Morris MI, Lu K, McDermott JK, Mone T, Orlowski JP, Dadhania DM, Abbott K, Horslen S, Laskin BL, Mougdil A, Venkat VL, Korenblat K, Kumar V, Grossi P, Bloom RD, Brown K, Kotton CN, Kumar D.Solid Organ Transplantation From Hepatitis B Virus-Positive Donors: Consensus Guidelines for Recipient Management. Am J Transplant. 2015 Feb 23. doi: 10.1111/ajt.13187. [Epub ahead of print]

Roland ME, Barin B, Huprikar S, Murphy B, Hanto DW, Blumberg E, Olthoff K, Simon D, Hardy WD, Beatty G, Stock PG; HIVTR Study Team. Survival in HIV-positive transplant recipients compared with transplant candidates and with HIV-negative controls. AIDS. 2016 Jan 28;30(3):435-44.

To find our clinical trials please click here.