Current NIH Grants

Active NIH Grants as of July 1, 2013, to Mount Sinai in the areas of Neuroscience and Psychiatry, from NIMH, NIDA, NIAAA, NIGMS, NIA and NINDS.

Area and Project Title

Principal Investigator

   
Aging & Alzheimer's Disease  
ESTROGEN INFLUENCES ON COGNITIVE AGING IN THE MONKEY BAXTER, MARK G
CHARACTERIZATION OF AN FAD PATHOGENIC PS1 MUTATION WITH COMPLETE LOSS OF ACTIVITY BRAUTIGAM, HANNAH
EVIDENCE FOR GAMMA-SECRETASE DYSFUNCTION IN SPORADIC AD GANDY, SAMUEL E
MODEL FOR SORCS1-MEDIATED DIABETES WITH DEMENTIA GANDY, SAMUEL E
GENERATION AND CHARACTERIZATION OF ALZHEIMER BRAIN CELLS GANDY, SAMUEL E
IMPACT OF PALLIATIVE CARE ON HEALTHCARE UTILIZATION OF SERIOUSLY ILL OLDER ADULTS GELFMAN, LAURA PILAR
ESTROGEN INFLUENCES ON NEUROENDOCRINE AGING GORE, ANDREA C
MODELING CELLULAR DETERMINANTS OF COGNITIVE DECLINE IN AGING HOF, PATRICK R
CHEMOANATOMIC CHANGES ASSOCIATED WITH AGING IN VESTIBULO-SYMPATHETIC PATHWAYS HOLSTEIN, GAY R
GERIATRIC PAIN CARE IN THE EMERGENCY DEPARTMENT HWANG, ULA Y
IMPROVING MANAGEMENT OF ACUTE PAIN FOR OLDER ADULTS IN THE ED SETTING HWANG, ULA Y
IMPROVING CARE FOR OLDER ADULTS WITH SERIOUS ILLNESS KELLEY, AMY STEVES
GLUTAMATE RECEPTORS IN AGING CORTICAL CIRCUITS MORRISON, JOHN H.
ESTROGEN AND THE AGING BRAIN MORRISON, JOHN H
ESTROGEN AND CORTICAL CIRCUITRY MORRISON, JOHN H
PATIENT ORIENTED RESEARCH IN PALLIATIVE CARE AND AGING MORRISON, R. SEAN
INFORMING/IMPROVING ICU PALLIATIVE CARE FOR OLDER ADULTS NELSON, JUDITH E
PILOT TRIAL OF CARVEDILOL IN ALZHEIMER'S DISEASE PASINETTI, GIULIO MARIA
PS1 REGULATES PROCESSING AND SIGNALING OF EPHRINB/EPHB ROBAKIS, NIKOLAOS K
PS1 MEDIATES THE NEUROPROTECTIVE FUNCTIONS OF THE EPHRINB/EPHB SYSTEM ROBAKIS, NIKOLAOS K
FE65-TSH-MEDIATED REGULATION OF GENE EXPRESSION IN ALZHEIMER'S DISEASE SAKURAI, TAKESHI
ALZHEIMER'S DISEASE RESEARCH CENTER SANO, MARY
INFLAMMATION, LONG-TERM DIABETES CHARACTERISTICS, AND COGNITIVE DECLINE SCHNAIDER BEERI, MICHAL
CONTROLLED EXPRESSION OF A CYSTATIN C-PEPTIDE AS THERAPY FOR ALZHEIMER'S DISEASE SHAW, PHYLLIS ANN
   
Autism  
IDENTIFYING THERAPEUTIC TARGETS FOR AUTISM USING SHANK3-DEFICIENT MICE BUXBAUM, JOSEPH D.
POPULATION-BASED AUTISM GENETICS & ENVIRONMENT STUDY BUXBAUM, JOSEPH D.
   
Child Psychiatry  
8/8-COLLABORATIVE GENOMIC STUDIES OF TOURETTE DISORDER COFFEY, BARBARA JANE
6/8-COLLABORATIVE GENOMIC STUDIES OF TOURETTE DISORDER GRICE, DOROTHY E
IMAGING STIMULANT AND NONSTIMULANT TREATMENTS FOR ADHD: A NETWORK-BASED APPROACH NEWCORN, JEFFREY H 
   
Depression, Stress, Anxiety  
REMODELING NEURONAL CHROMATIN IN MOUSE MODELS FOR DEPRESSION AKBARIAN, SCHAHRAM
METHYL-BINDING PROTEINS IN RODENT DEPRESSION MODELS AKBARIAN, SCHAHRAM
HISTONE VARIANTS IN RODENT DEPRESSION MODELS ALLIS, CHARLES DAVID
NOVEL ROLE FOR SIRTUIN SIGNALING MECHANISMS AND DOWNSTREAM TARGETS IN DEPRESSION FERGUSON, DEVEROUX
IH AND K+ CHANNELS AS MECHANISTICALLY NOVEL TARGETS FOR DEPRESSION TREATMENT FRIEDMAN, ALLYSON KIMBERLY
NEUROPHYSIOLOGICAL BASIS OF SUSCEPTIBILITY AND RESILIENCE TO SOCIAL DEFEAT STRESS HAN, MING-HU 
1/8-PROLONGING REMISSION IN DEPRESSED ELDERLY (PRIDE) KELLNER, CHARLES H
FUNCTIONAL MRI STUDIES OF EMOTION IN DEPRESSION AND RAPID ANTIDEPRESSANT RESPONSE MURROUGH, JAMES
PHARMACOLOGICAL ACTIONS OF ANTIDEPRESSANTS TREATMENTS NESTLER, ERIC J
EPIGENETIC MECHANISMS OF DEPRESSION NESTLER, ERIC J
MECHANISMS OF STRUCTURAL PLASTICITY IN STRESS-RELATED DISORDERS RUSSO, SCOTT J
VGF FUNCTION IN DEPRESSION AND ANTIDEPRESSANT TREATMENT SALTON, STEPHEN R
NEURAL CIRCUIT BASIS OF BEHAVIORAL SUSCEPTIBILITY AND RESILIENCE TO SOCIAL DEFEAT WALSH, JESSICA
   
Epigenetics and Genomics  
EPIGENOME MAPPING IN CORTICAL INTERNEURONS AKBARIAN, SCHAHRAM
DOPAMINERGIC EPIGENOMES FROM HUMAN BRAIN AKBARIAN, SCHAHRAM  
BIOREPOSITORY FOR GENOMIC MEDICINE IN DIVERSE COMMUNITIES BOTTINGER, ERWIN P.
NEURODEVELOPMENTAL EFFECTS OF CANNABIS AND ITS EPIGENETIC REGULATION HURD, YASMIN L
MULTIGENERATIONAL EPIGENETIC EFFECTS OF CANNABIS EXPOSURE HURD, YASMIN L
PRENATAL CANNABIS EXPOSURE AND EPIGENETIC MECHANISMS UNDERLYING VULNERABILITY TO MORRIS, CLAUDIA VARGAS
CHROMATIN AND GENE REGULATION IN COCAINE AND OPIATE ADDICTION NESTLER, ERIC J.
REPRESSIVE HISTONE AND DNA METHYLATION IN RODENT DEPRESSION MODELS NESTLER, ERIC J
SOFTWARE FOR THE ANALYSIS OF LARGE-SCALE GENOTYPING AND SEQUENCING STUDIES PURCELL, SHAUN M
SEX DIFFERENCES IN STRESS-INDUCED GENOME-WIDE TRANSCRIPTIONAL PROFILES RUSSO, SCOTT J
COMPREHENSIVE IDENTIFICATION OF PARENT OF ORIGIN EFFECTS IN HUMAN AND MOUSE SHARP, ANDREW JAMES
2/6 THE GENETICS OF ENDOPHENOTYPES AND SCHIZOPHRENIA SIEVER, LARRY J
4/4-PSYCHIATRIC GWAS CONSORTIUM:GENOMIC FOLLOW-UP NEXT-GEN SEQUENCING & GENOTYPI SKLAR, PAMELA
2/2-A LARGE-SCALE SCHIZOPHRENIA ASSOCIATION STUDY IN SWEDEN SKLAR, PAMELA
1/3-NETWORKS FROM MULTIDIMENSIONAL DATA FOR SCHIZOPHRENIA AND RELATED DISORDERS SKLAR, PAMELA  
EPIGENETIC MECHANISMS OF DEPRESSION IN HUMAN LIMBIC CIRCUITS TAMMINGA, CAROL A.
OCT4 AND EPIGENETIC REGULATION OF STEM CELL PLURIPOTENCY WANG, JIANLONG
CHEMICAL GENOMICS PARADIGM FOR EPIGENTIC REGULATION ZHOU, MING-MING
   
HIV/AIDS  
OPTIMIZING VITAMIN D TREATMENT IN HIV/AIDS: AN RCT BRANCH, ANDREA D. 
IMAGING VIROLOGICAL SYNAPSES DURING PARENTERAL HIV TRANSMISSION CHEN, BENJAMIN 
THE MOUNT SINAI INSTITUTE FOR NEUROAIDS DISPARITIES MORGELLO, SUSAN 
THE MANHATTAN HIV BRAIN BANK MORGELLO, SUSAN 
HIV-ASSOCIATED NEUROPATHY: ETHNIC DISPARITIES AND PATHOGENESIS ROBINSON-PAPP, JESSICA 
   
Memory & Cognition  
ESTROGEN INFLUENCES ON COGNITIVE AGING IN THE MONKEY BAXTER, MARK G
MODELING CELLULAR DETERMINANTS OF COGNITIVE DECLINE IN AGING HOF, PATRICK R
INFLAMMATION, LONG-TERM DIABETES CHARACTERISTICS, AND COGNITIVE DECLINE SCHNAIDER BEERI, MICHAL
ASTROCYTIC CONTRIBUTIONS TO LONG TERM MEMORY & SYNAPTIC PLASTICITY STERN, SARAH 
   
Schizophrenia and Bipolar Disorder  
STRUCTURE AND FUNCTION OF THE 5HT2A/MGLUR2 COMPLEX IN SCHIZOPHRENIA GONZALEZ-MAESO, JAVIER 
CONTRIBUTION OF CELL CYCLE PROCESSES TO MYELIN DEFICITS IN SCHIZOPHRENIA HAROUTUNIAN, VAHRAM
EFFICACY AND SAFETY OF GALANTAMINE FOR DYSFUNCTION IN BIPOLAR DISORDER IOSIFESCU, DAN VLAD
ROLE OF DISC1 AND NRG1 IN OLIGODENDROCYTE DEVELOPMENT IN SCHIZOPHRENIA KATSEL, PAVEL LEON
2/6 THE GENETICS OF ENDOPHENOTYPES AND SCHIZOPHRENIA SIEVER, LARRY J
A D1 AGONIST FOR WORKING MEMORY ENHANCEMENT IN THE SCHIZOPHRENIA SPECTRUM SIEVER, LARRY J
2/2-A LARGE-SCALE SCHIZOPHRENIA ASSOCIATION STUDY IN SWEDEN SKLAR, PAMELA
1/3-NETWORKS FROM MULTIDIMENSIONAL DATA FOR SCHIZOPHRENIA AND RELATED DISORDERS SKLAR, PAMELA  
   
Substance Abuse  
HEROIN WITHDRAWAL: MODULATION OF AVERSIVE STATES BY KAPPA OPIOID RECEPTORS CAMMACK, KATHARINE M. 
ALCOHOL-INDUCED FATTY LIVER AND INJURY IN HUMANIZED CYP2E1 KNOCKIN MICE. CEDERBAUM, ARTHUR I 
ROLE OF AUTOPHAGY ON THE MODULATION OF CYP2E1 ALCOHOL LIVER TOXICITY CEDERBAUM, ARTHUR I
POST-TRANSLATIONAL REGULATION OF OPIOID AND CANNABINOID RECEPTORS DEVI, LAKSHMI A
POST-TRANSLATIONAL REGULATION OF OPIOID RECEPTORS DEVI, LAKSHMI A
THE EFFECTS OF COCAINE ON THE WNT SIGNALING PATHWAY IN THE NUCLEUS ACCUMBENS DIAS, CAROLINE MARIE
PROBING THE LINK BETWEEN RNA EDITING AND DRUG ADDICTION DRACHEVA, STELLA
A COMBINATION OF SCHEDULED REDUCED SMOKING WITH VARENICLINE TO ENHANCE CESSATION ERBLICH, JOEL
DYNAMIC MECHANISMS OF GPCRS TARGETED BY DRUGS OF ABUSE FILIZOLA, MARTA
OXIDANT STRESS AND FIBROSIS IN ALCOHOLIC LIVER INJURY FRIEDMAN, SCOTT
AUTOPHAGY DURING HEPATIC STELLATE CELL ACTIVATION IN ALCOHOLIC LIVER INJURY FRIEDMAN, SCOTT
MACHINE LEARNING DISCOVERY OF PATTERNS OF SELF REGULATION IN DRUG ADDICTION AND I GOLDSTEIN, RITA Z
DISSECTION OF SREBP/ATF6 CROSSTALK IN ALCOHOL-INDUCED STEATOSIS HOWARTH, DEANNA L.
THE OPIOID MESOLIMBIC SYSTEM IN HEROIN ABUSE HURD, YASMIN L
THE NEURONAL BASIS OF CANNABIS-INDUCED DEVELOPMENTAL DEFICITS IN THE CNS HURD, YASMIN L
CANNABIDIOL AS TREATMENT INTERVENTION FOR OPIATE RELAPSE HURD, YASMIN L
INTERACTIONS BETWEEN SHH PATHWAY REGULATORS AND FETAL ALCOHOL EXPOSURE IN MICE KRAUSS, ROBERT S.
PREDICTING ADVERSE CARDIOVASCULAR EVENTS IN EMERGENCIES DUE TO DRUG OVERDOSE MANINI, ALEX FRANCIS
MOLECULAR STUDIES OF COCAINE ACTION IN BRAIN NESTLER, ERIC J
ROLE OF CREB IN OPIATE AND COCAINE ADDICTION NESTLER, ERIC J
MOLECULAR NEUROBIOLOGY OF DRUG ADDICTION NESTLER, ERIC J
NEUROTROPHIC MECHANISMS IN OPIATE AND COCAINE ACTION NESTLER, ERIC J
NEUROADAPTATIONS IN DRUG SELF-ADMINISTRATION AND RELAPSE SELF, DAVID W
STRUCTURAL ANALYSIS OF ALCOHOL-DEPENDENT ACTIVATION OF GIRKS SLESINGER, PAUL A
DEVELOPMENT AND ANALYSIS OF HIPSCS FOR STUDIES ON ADDICTION SLESINGER, PAUL A
   
Traits/States  
MOLECULAR DETERMINANTS OF INDIVIDUAL DIFFERENCES IN FEAR REACTIVITY AND RECOVERY DRACHEVA, STELLA  
THE NEUROIMMUNOLOGY OF ANHEDONIA GABBAY, VILMA
INHIBITORY SYNAPTIC CONTROL OF SOCIAL AVOIDANCE BEHAVIOR HESHMATI, MITRA
AN FMRI STUDY OF THE ENHANCEMENT OF EMOTION REGULATION IN BORDERLINE PATIENTS KOENIGSBERG, HAROLD W
5HTT AND 5-HT2A RECEPTORS IN IMPULSIVE AGGRESSION AND EFFECTS OF FLUOXETINE SIEVER, LARRY J
NEURAL BASIS OF BEHAVIORAL AROUSAL WEISS, KLAUDIUSZ ROBERT
NEURAL BASIS OF BEHAVIORAL FLEXIBILITY WEISS, KLAUDIUSZ ROBERT
   
Basic Research in Neuroscience  
A CONNECTIVITY-BASED SYNAPTOME BENSON, DEANNA L
ROLE OF SEMA7A IN FUNCTIONAL ORGANIZATION OF NEOCORTEX BENSON, DEANNA L
HISTONE DEACETYLATION IN OLIGODENDROCYTE DIFFERENTIATION CASACCIA, PATRIZIA
ROLE OF CELL CYCLE REGULATORS IN DIFFERENTIATION CASACCIA, PATRIZIA
NEURAL BASIS OF BEHAVIORAL PLASTICITY IN A SIMPLE SYSTEM CROPPER, ELIZABETH C 
ENZYMES INVOLVED IN NEUROPEPTIDE BIOSYNTHESIS AND REGULATION DEVI, LAKSHMI A 
OPTICAL PROBES FOR CONTROLLING CELLULAR FUNCTION ELLIS-DAVIES, GRAHAM
STRUCTURAL ASPECTS OF OLIGOMERIZATION IN THE FUNCTION OF GPCRS FILIZOLA, MARTA 
THE ROLE OF ASTROCYTES IN MEMORY CONSOLIDATION GAO, VIRGINIA
BRAIN AROMATASE AVAILABILITY IN STEROID USERS: PET STUDIES WITH [11C]VOROZOLE HILDEBRANDT, THOMAS B
DNA METHYLATION IS NECESSARY FOR THE ACQUISITION OF AN OLIGODENDROCYTE IDENTITY HUYNH, JIMMY
ASTROCYTE REGULATION OF CNS REMYELINATION JOHN, GARETH R
REACTIVE ASTROGLIOSIS REGULATES BLOOD-BRAIN BARRIER PERMEABILITY. JOHN, GARETH R
GLOBAL & SYSTEMS LEVEL ANALYSES OF CELL FATE REGULATION LEMISCHKA, IHOR R
ACQUISITION AND MAINTENANCE OF DNA METHYLATION IN GENOMIC IMPRINTING LI, XIAJUN
CELLULAR ACTIONS OF CREB AND DFOSB IN REWARD NEURONS MALENKA, ROBERT C
ESTROGEN-REGULATED PLASTICITY OF HIPPOCAMPAL NEURONS MCEWEN, BRUCE S.
TEMPORAL REQUIREMENTS FOR N-CADHERIN IN MAINTAINING STABILITY OF SYNAPSES NIKITCZUK, JESSICA
SMALL MOLECULE LIBRARIES TARGETED TO CBP AND ATTENUATION AFOSB EXPRESSION OHLMEYER, MICHAEL  
LEVERAGING IDENTITY-BY-DESCENT INFORMATION IN LARGE-SCALE POPULATION SEQUENCING PURCELL, SHAUN M
COGNATE MICROGLIA-NEURON INTERACTION AND ITS ROLE IN INFLAMMATION SCHAEFER, ANNE
CORRECTION OF OBESITY BY OPTOGENETIC MANIPULATION OF STRIATAL NEURONS SCHWARTZ, ELIZABETH
PATTERNING OF THE VERTEBRATE NERVOUS SYSTEM SOKOL, SERGEI Y
IDENTIFICATION OF NOVEL INHIBITORS TARGETING ENTRY OF HUMAN CYTOMEGALOVIRUS TORTORELLA, DOMENICO
IDENTIFICATION OF INHIBITORS THAT STABILIZE ER DEGRADATION SUBSTRATES TORTORELLA, DOMENICO
ROLE OF FSH IN OSREOCLAST FORMATION AND FUNCTION ZAIDI, MONE
PROMOTING AXON REGENERATION BY ACTIVATION OF THE SMAD1 SIGNALING PATHWAY ZOU, HONGYAN JENNY
   
Neurology  
FACTORS DETERMINING PLACEBO RESPONSE IN DRUG-RESISTANT FOCAL EPILEPSY BAGIELLA, EMILIA
HIGH RESOLUTION MAGNETIC RESONANCE IMAGING AND SPECTROSCOPY OF EPILEPSY AT 7T BALCHANDANI, PRITI
ALCOHOL-INDUCED FATTY LIVER AND INJURY IN HUMANIZED CYP2E1 KNOCKIN MICE. CASACCIA, PATRIZIA
THE TRAJECTORY OF FUNCTIONAL STATUS AND QUALITY OF LIFE BEFORE AND AFTER STROKE DHAMOON, MANDIP SINGH
SEARCH FOR GENES INFLUENCING CHILDHOOD ABSENCE EPILEPSY DURNER, MARTINA
NOVEL MRI MARKERS IN PROGRESSIVE MULTIPLE SCLEROSIS INGLESE, MATILDE
EXTENSION OF COMBINATION THERAPY FOR MULTIPLE SCLEROSIS LUBLIN, FRED D
A RANDOMIZED TRIAL OF UNRUPTURED BRAIN AVMS (ARUBA)-STAT MOSKOWITZ, ALAN J
GENE DISCOVERY IN PRIMARY DYSTONIA USING WHOLE EXOME SEQUENCING OZELIUS, LAURIE J.
ELUCIDATING AND UNDERSTANDING THE GENETIC BASIS OF MOVEMENT DISORDERS PAISAN-RUIZ, CORO
DISSECTING THE GENETIC UNDERPINNINGS OF ESSENTIAL TREMOR PAISAN-RUIZ, CORO
BRAIN TORSINA AND CHILDHOOD-ONSET DYSTONIA SHASHIDHARAN, PULLANIPALLY 
MOLECULAR MECHANISM OF LRRK2 BIOLOGY AND PATHOLOGY IN PARKINSON'S DISEASE YUE, ZHENYU
CELLULAR AND MOLECULAR BASIS FOR INITIAL PD PATHOGENIC EVENTS IN LRRK2 BAC MODELS YUE, ZHENYU  
   
Research Training  
RESEARCH TRAINING FOR MEDICAL GENETICISTS AT MOUNT SINAI SCHOOL OF MEDICINE DESNICK, ROBERT J
INTERDISCIPLINARY TRAINING IN DRUG ABUSE RESEARCH DEVI, LAKSHMI A
MENTORING JUNIOR FACULTY IN ALCOHOLIC LIVER DISEASE FRIEDMAN, SCOTT LAURENCE
MOUNT SINAI MEDICAL SCIENTIST TRAINING PROGRAM HURD, YASMIN L
INTEGRATED TRAINING IN PHARMACOLOGICAL SCIENCES KRULWICH, TERRY ANN
CENTER FOR COLLABORATIVE INNER CITY MENTAL HEALTH SERVICES RESEARCH (CCCR) MCKAY, MARY MCKERNAN
TRAINING PROGRAM IN CELLULAR AND MOLECULAR BIOLOGY MLODZIK, MAREK 
TRAINING PROGRAM IN NEUROSCIENCE SALTON, STEPHEN R
MOUNT SINAI NEUROLOGY RESIDENT-RESEARCHER TRAINING PROGRAM SEALFON, STUART C.
TRAINING PROGRAM IN MENTAL HEALTH RESEARCH SHAPIRO, MATTHEW L 
CEREBROVASCULAR RESEARCH TRAINING PROGRAM TUHRIM, STANLEY
THE NINDS MASS SPECTROMETRY PROTEOMICS CENTER FOR NEUROSCIENCES AT MSSM WANG, RONG

 

 


Contact Us

Tel: 212-659-8734

Icahn School of Medicine
Department of Psychiatry
Box 1230
One Gustave L. Levy Place
New York, NY 10029