Autism and Other Childhood Mental Illnesses

Autism is a developmental disorder characterized by deficits in social interaction and language use, as well as the presence of repetitive behaviors and other symptoms. These core characteristics present to varying degrees in different individuals. Because of this, autism is considered to occur along a spectrum, which refers to the wide range of symptoms and levels of disability people with autism can exhibit. The Seaver Autism Center is a fully integrated and translational center dedicated to discovering the biological causes of autism and developing breakthrough treatments. The Center leads progressive research studies while providing comprehensive, personalized care to children and adults with autism spectrum disorders. Its mission is to prevent and cure autism by bridging the gap between new discoveries at the basic science level and enhanced clinical care that provides new and improved approaches to the community for caring for people with autism.

Our Research

Under the direction of Joseph D. Buxbaum, PhD, the Seaver Autism Center works with The Friedman Brain Institute and functions as the core of autism research at Mount Sinai. The Center features a multidisciplinary team of experts that uses genetics, molecular biology, model systems, neuroimaging, and experimental therapeutics, including behavioral and pharmacological interventions, to understand the causes of autism and related conditions. These studies lead to novel drug targets and better treatments. Learn more.

Treatment at Mount Sinai

The Autism Clinical Program at the Seaver Center is a comprehensive assessment and treatment program that provides the highest level of patient care supported by cutting-edge research in the field. The Clinical Program integrates a diverse research portfolio with state-of-the-art clinical care in order to provide services to the community, such as:

Clinical Trials

The Experimental Therapeutics Program at the Seaver Autism Center is using recent advances in genetic technology to identify causal genes in autism spectrum disorder (ASD) and to develop animal models, which replicate the human condition. These models allow us to understand the effects of genetic variants on brain function and to determine which molecular signaling pathways are affected in ASD. Once clarified, this information is used to discover specific targets for treatment development, first tested in the model systems, and then in clinical trials in affected children, adolescents, and adults.

Contact Us

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Phone: 212-241-0961
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Icahn School of Medicine at Mount Sinai
Department of Psychiatry
Box 1668
One Gustave L. Levy Place