About the Tumor CytoGenomics Laboratory 

Mount Sinai’s Tumor CytoGenomics Laboratory provides state-of-the-art services in the detection of acquired chromosomal abnormalities associated with hematological malignancies and solid tumors. The field of cytogenetics (the science of chromosomes) greatly impacts the clinical management of patients and the understanding of the basic biology of these disorders. Our Laboratory offers all available cytogenetic techniques to identify the type and nature of complex structural abnormalities present in malignant (cancerous) cells. These technologies are integral diagnostic and prognostic tools in Hematology and Oncology. The Tumor CytoGenomics Laboratory at the Mount Sinai Health System offers a full range of services for clinicians and researchers from Sinai and beyond. 

We provide services with fast turnaround times for chromosome analysis (G-banding and Multicolor metaphase analysis) and fluorescence in situ hybridization (FISH) assays, using over 100 FISH probes, in more than 15,000 clinical tests each year. We utilize a GSL (genetic slide loader), which is a fully automated system for scanning and imaging metaphase cells from up to 124 slides. Our team includes medical technologists, all licensed by the New York State Department of Education. 

The Tumor CytoGenomics Laboratory is a major collaborator in international, multicenter clinical trials such as COG (Childhood Oncology Group) and CALGB (Cancer and Leukemia GroupB). Most notably, we are the core Laboratory for the International MPN (myeloproliferative neoplasms) Research Clinical Consortium. Our Laboratory is accredited by the New York State Department of Health (NYSDOH) and College of American Pathologists (CAP). 

Our mission is to enhance the quality of clinical and molecular cytogenomic service through the development and implementation of state-of-art technologies to constantly improve patient care, education, and clinical research.


Contact Us

Tumor CytoGenomics Laboratory
The Mount Sinai Health System 
1428 Madison Avenue (Atran Building) 
2nd floor, Room 250 
New York, NY 10029 

Phone: 212-241-8801 
Fax: 212-426-2427 

Director: Vesna Najfeld 
Hours: 6:00am – 7:00pm, Monday through Friday (except hospital holidays
9:00am – 5:00pm, Saturday (except hospital holidays)