Comparative Pathology Diagnostic Laboratory (CPDL)
The CPDL provides in-house gross anatomic pathology and clinical pathology services in support of the research programs at the Mount Sinai Medical Center and the clinical programs of the Center for Comparative Medicine and Surgery (CCMS).
The lab is under the direction of a full-time veterinary pathologist. Staff includes a laboratory manager and two full-time laboratory technicians. The primary laboratory is located on the 26th floor of Annenberg, Room 26-92. Laboratory support areas are two necropsy suites, Room 26-93 and Icahn Medical Institute S1-27H. Both necropsy rooms are well equipped (down draft tables, biosafety hood, dissecting tools, and photographic equipment) and available for use by the research community. Laboratory equipment includes: Bio-Plex 200 System from Bio-Rad for performing serology test for viral panels detection. Microscopes: individual (light, phase contract, fluorescent, microphotography), doubled-headed with video color camera attached to a Sony video monitor. Ancillary equipment for bacteriology, histology Sekura Processor, Fisher embedding Center and Hacker Automatic Linear Stainer, and GeneAMP (Perkin Elmer) PCR equipment.
Although the majority of diagnostics are performed in-house, commercial and academic labs are used for confirmation of positive serology results. Nonhuman primate virology is also performed by commercial labs. The following materials are sent to reference laboratories: simian serology panel, rodent pathogen MAP testing (IMPACT) for cell lines or tumors, endocrinology tests, and other special assays. Those commercial and academic labs include: Charles River Lab, Antech Diagnostics Lab, BioReliance Lab, AnMed Biosafe, RADIL in Missouri University.
The CPDL works closely with several existing SRF facilities on campus (Biorepository/Histology SRF and qPCR SRF) to increase the support available to the research community.