Research

The laboratories supervised by the full-time faculty focus primarily on immunologic mechanisms and disorders; some of the major areas of interest currently include:

  • B and T cell growth and differentiation
  • Control mechanisms of immunoglobulin production
  • Mucosal immunology
  • Genetics of B cell diseases
  • B cell activation by TLR agonists
  • Bioinformatics of allergic diseases
  • Murine models of airway hyper-reactivity
  • Asthma in aging
  • Anaphylaxis
  • Computer analysis of immune deficiency states
  • Food protein induced enterocolitis syndrome (FPIES)
  • Eosinophilic esophagitis
  • Novel therapies for food allergies
  • Allergen characterization – B cell epitopes
  • Antigen-presenting cells in food allergy
  • T cell immunophenotypic changes secondary to immunotherapy in food allergy
  • Basophil activation assays
  • Murine models of food allergy and immunotherapy
  • Murine models of airway hyper-reactivity