Ming-Ming Zhou, PhD, is Professor and Chair of the Department of Structural and Chemical Biology, Professor of Oncological Sciences, and Professor of Pharmacology and Systems Therapeutics.  Read More

The Department of Structural and Chemical Biology

The Mount Sinai Department of Structural and Chemical Biology is dedicated to addressing the most challenging problems in human biology and disease at the basic molecular level using structural biology, biophysics, chemical biology, and computational methods.  We aim to advance science and medicine through studying atomic structure, molecular function and regulation of biological macromolecules, designing novel small molecules to elucidate biology and disease mechanisms, and developing new therapeutics for treatment.

Protein-Nucleic Acid Interactions

The Aggarwal laboratory studies how enzymes and transcriptional and translational regulators interact with nucleic acids to affect cellular development and disease outcome.

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Computational Biophysics of Membrane Proteins

The Filizola Laboratory uses computational structural biology tools to achieve a detailed mechanistic understanding of signal transduction processes triggered by molecular recognition in membrane protein complex systems such as G-protein-coupled receptors (GPCRs) and platelet integrin aIIbb3.

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Contact Us

Yoori Kim
Department Administrator
Send e-mail
Tel: 212-659-8651
Fax: 212-849 -2456

Arnaldo Medina
Administrative Assistant
Send e-mail
Tel: 212-659-8647
Fax: 212-849 -2456

Icahn School of Medicine at Mount
Sinai, Department of Structural &
Chemical Biology
One Gustave L. Levy Place, Box 1677
New York, NY 10029
Tel: 212-659-8647
Fax: 212-849-2456