At the Manhattan HIV Brain Bank, we are involved in a wide range of translational research projects focused on AIDS pathogenesis. A sampling of our publications follows.

Bonwetsch R, Croul S, Richardson MW, Lorenzana C, Valle LD, Sverstiuk AE, Amini S, Morgello S, Khalili K, Rappaport J. Role of HIV-1 tat and CC chemokine MIP-1alpha in the pathogenesis of HIV-associated central nervous system disorders. J Neurovirol 1999, 5(6):685-694. 

Morgello S, DiRocco A, Simpson DM. Current Views on Common Neurologic Manifestations of HIV. The PRN Notebook 2000, 5(3):19-25.

Geraci A, DiRocco A, Liu M, Werner P, Tagliati M, Godbold J, Simpson D, Morgello S. AIDS-myelopathy is not associated with elevated HIV viral load in cerebrospinal fluid. Neurology 2000, 55(3):440-442.

DelValle L, Croul S, Morgello S, Amini S, Rappaport J, Khalili K. Detection of HIV-1 tat and JCV capsid protein, VP1, in AIDS brain with progressive multifocal leukoencephalopathy. J Neurovirol 2000, 6:221-228.

Bruggeman LA, Ross MD, Tanji N, Cara A, Dikman S, Gordon RE, Burns GC, D’Agati VD, Winston JA, Klotman ME, Klotman PE. Renal Epithelium is a previously unrecognized site of HIV-1 Infection. J Am Soc Nephrol 2000, 11:2079-2087.

Zhao ML, Kim MO, Morgello S, Lee SC. Expression of inducible nitric oxide synthase, interleukin-1, and caspase-1 in HIV-1 encephalitis. J Neuroimmunol 2001, 115:182-191.

Fiala M, Liu QN, Reddy S, Graves MC. Macrophages infiltrate brain and express COX-2 and iNOS in Alzheimer’s disease and AIDS. Alzheimer’s reports 2001, 4(1):1-7.

Liu QN, Reddy S, Sayre JW, Pop V, Graves MC, Fiala M. Essential role of HIV type 1-infected and cyclooxygenase 2-activated macrophages and T cells in HIV type 1 myocarditis. AIDS Res Hum Retrovirus 2001, 17(15):1423-1433.

Fisher-Smith T, Croul S, Sverstiuk AE, Capini C, L’Heureux D, Regulier E, Richardson MW, Amini S, Morgello S, Khalili K, Rappaport J. CNS invasion by CD14+/CD16+ peripheral blood-derived monocytes in HIV dementia: Perivascular accumulation and reservoir of HIV infection. J Neurovirol 2001, 7(6):528-541.

Morgello S, Gelman BB, Kozlowski PB, Masliah E, Cornford M, Vinters HV, Cavert W, Grant I , Singer EJ. The National NeuroAIDS Tissue Consortium:  A New Paradigm in Brain Banking with an Emphasis on Infectious Disease. Neuropathology and Applied Neurobiology, 2001, 27:326-335.

Byne W, Tobet S, Mattiace LA, Lasco MS, Kemether E, Edgar MA, Morgello S, Buchsbaum MS, Jones LB. The interstitial nuclei of the human anterior hypothalamus: An investigation of variation with sex, sexual orientation, and HIV status. Hormones and Behavior 2001, 40:86-92.

Ghorpade A, Persidskaia R, Suryadevara R, Che M, Liu XJ, Persidsky Y, Gendelman HE.  Mononuclear phagocyte differentiation, activation, and viral infection regulate matrix metalloproteinase expression: Implications for human immunodeficiency virus type 1-associated dementia. J Virol 2001, 75(14):6572-6583.

Morgello S, Mahboob R, Yakoushina T, Khan S, Hague K. Autopsy findings in an HIV-infected population over two decades: Influences of gender, race, HIV risk, and time. Arch Pathol Lab Med 2002, 126:182-190.

Rottnek M, diRocco A, Laudier D, Morgello S. Axonal damage is a late component of vacuolar myelopathy. Neurology 2002, 58:479-481.

Walker RH, Morgello S, Davidoff-Feldman B, Melnick A, Walsh MJ, Shashidharan P, Brin MF. Autosomal dominant chorea-acanthocytosis with polyglutamine-containing neuronal inclusions.  Neurology 2002, 58:1031-1037.

Del Valle L, Gordon J, Enam S, Delbue S, Croul S, Abraham S, Radhakrishnan S, Assimakopoulou M, Katsetos C, Khalili K. Expression of human neurotropic polyomavirus JCV late gene product agnoprotein in human medulloblastoma. J Natl Cancer Inst 2002; 94:267-273.

DiRocco A, Bottiglieri T, Werner P, Geraci T, Simpson D, Godbold J, Morgello S. Abnormal cobalamin-dependent transmethylation in AIDS-associated myelopathy. Neurology 2002, 58: 730-735.

Sweet T, Del Valle L, and Khalili K: Molecular biology and immunoregulation of human neurotropic JC virus in CNS. Journal of Cell Physiology 2002, 191(3): 249-256.

Lasco MS, Jordan TJ, Edgar MA, Petito CK, Byne W: A lack of dimorphism of sex or sexual orientation in the human anterior commissure. Brain Research 2002, 936:95-98.

Si Q, Cosenza M, Zhao ML, Goldstein H, Lee SC: GM-CSF and M-CSF modulate -chemokine and HIV-1 expression in microglia. Glia 2002, 39:174-183.

Cosenza M, Zhao M-L, Si Q, Lee SC: Human brain parenchymal microglia express CD14 and CD45 and are productively infected by HIV-1 in HIV-1 encephalitis. Brain Pathol 2002, 12(4):442-455.

Cosenza M, Zhao ML, Shankar SL, Shafit-Zagardo B, Lee SC: Upregulation of MAP2e-expressing oligodendrocytes in the white matter of patients with HIV-1 encephalitis. Neuropathol Appl Neurobiol 2002, 28:480-488.

Fiala M, Liu N, Sayre J, Pop V, Brahmandam V, Graves MC, Vinters HV: Cyclooxygenase-2-positive macrophages infiltrate the Alzheimer’s disease brain and damage the blood-brain barrier. European Journal of Clinical Investigation 2002, 32(5):360-371.

Twu C, Liu NQ, Popik W, Bukrinsky M, Sayre J, Roberts J, Rania S, Bramhandam V, Roos KP, MacLellan WR, Fiala M: Cardiomyocytes undergo apoptosis in human immunodeficiency virus cardiomyopathy through mitochondrion- and death receptor-controlled pathways. Proc Natl Acad Sci 2002, 99(22): 14386-14391.

Wang JY, Peruzzi F, Lassak A, DelValle L, Rappaport J, Khalili K, Amini S, Reiss K: Neuroprotective effects of IGF-1 against TNF-alpha induced neuronal damage in HIV-associated dementia.  Virology 2003, 305:66-76.

Turchan J, Pocernich CB, Gairola C, Chauhan A, Schifitto G, Butterfield DA, Buch S, Narayan O, Sinai A, Geiger J, Berger JR, Elford H, Nath A. Oxidative stress in HIV demented patients and protection ex vivo with novel antioxidants. Neurology 2003, 60:307-314.

Trillo-Pazos G, Diamanturos A, Rislove L, Menza T, Chao W, Belem P, Sadiq S, Morgello S, Sharer L, Volsky D. HIV-1 DNA was isolated from microglia.macrophages, astrocytes, and neurons by laser capture microdissection and PCR from HIV encephalitis tissue. Brain Pathology 2003, 13(2):144-154.

Erichsen D, Lopez AL, Peng H, Niemann D, Williams C, Bauer M, Morgello S, Cotter RL, Ryan LA, Ghorpade A, Gendelman HE, Zheng J. Neuronal injury regulates fractalkine: relevance for HIV-1 associated dementia. J Neuroimmunol 2003, 138:144-155.

Sperber K, Beuria P, Singha N, Gelman I, Cortes P, Chen H, Kraus T. Induction of apoptosis by HIV-1-infected monocytic cells. J Immunol 2003, 170:1566-1578.

Walker RH, Good PF, Shashidharan P. TorsinA immunoreactivity in inclusion bodies in trinucleotide repeat diseases. Movement Disorders 2003, 18(9):1041-1044.

Suryadevara R, Holter S, Borgmann K, Persidsky R, Labenz-Zink C, Persidsky Y, Gendelman HE, Wu L, Ghorpade A. Regulation of tissue inhibitor of metalloproteinase-1 by astrocytes: Links to HIV-1 dementia. Glia 2003, 44: 47-56.

Radhakrishnan S, Otte J, Enam S, Del Valle L, Khalili K, Gordon J. JC Virus-induced changes in cellular gene expression in primary human astrocytes. J Virology 2003, 77(19):10638-10644.

Zhao  ML, Si Q, Lee SC. IL-16 expression in lymphocytes and microglia in HIV-1 encephalitis. J Neuropathol Appl Neurobiol 2003, 30:233-242.

Ryan L, Brester M, Bohac D, Morgello S, Zheng J. Upregulation of soluble TNF receptor two in plasma of HIV seropositive individuals who use opiates. AIDS Research and Human Retroviruses 2004, 20(1):41-45.

Woods SP, Rippeth JD, Frol AB, Levy JK, Ryan E,  Soukup VM,  Hinkin CH, Lazzaretto D, Cherner  M, Marcotte TD, Gelman BB, Morgello S, Singer EJ, Grant I,  Heaton RK. Interrater reliability of clinical ratings and neurocognitive diagnoses in HIV. Journal of Clinical and Experimental Neuropsychology 2004, 26(6):759-778.

Ryan EL, Morgello S, Isaacs K, Naseer M, Gerits P, Abromowitz L, Mantha L, Joseph G, The Manhattan HIV Brain Bank. Neuropsychiatric impact of hepatitis C on advanced HIV. Neurology 2004, 62:957-962.

Morgello S, Estanislao L, Simpson D, Geraci A, DiRocco A, Gerits P, Ryan E, YakoushinaT, Khan S, Mahboob R, Naseer M, Dorfman D, Sharp V, The Manhattan HIV Brain Bank. HIV-associated distal sensory polyneuropathy in the era of highly active antiretroviral therapy: The Manhattan HIV Brain Bank. Archives of Neurology 2004, 61:546-551.

Tse W Cersosimo MG, Gracies JM, Morgello S, Olanow CW, Koller W. Movement disorders and AIDS: A review. Parkinsonism and Related Disorders 2004, 10:323-334.

Fiala M, Popik W, Qiao JH, Lossinsky AS, Alce T, Tran K, Yang W, Roos KP, Arthos J. HIV-1 induces cardiomyopathy by cardiomyocyte invasion and gp120, tat and cytokine apoptotic signaling.  Cardiovascular Toxicology 2004, 4(2):97-108.

Enam S, Sweet TM, Amini S, Khalili K, DelValle L. Evidence for involvement of transforming growth factor B1 signaling pathway in activation of JC virus in human immunodeficiency virus 1-associated progressive multifocal leukoencephalopathy. Arch Pathol Lab Med 2004, 128:282-291.

Cannella B, Raine CS. Multiple sclerosis: Cytokine receptors on oligodendrocytes predict innate regulation. Ann Neurol 2004, 55(1):46-57.

Carlson KA, Limoges J, Pohlman GD, Poluektova LY, Langford D, Masliah E, Ikezu T, Gendelman HE. OTK18 expression in brain mononuclear phagocytes parallels the severity of HIV-1 encephalitis. J Neuroimmunology 2004, 150:186-198.

Smit TK, Brew BJ, Tourtellotte W, Morgello S, Gelman B, Saksena NK. Independent evolution of human immunodeficiency virus (HIV) drug resistance mutations in diverse areas of the brain in HIV-infected patients, with and without dementia, on antiretroviral treatment. J Virol 2004, 78(18):10133-10148.

Fischer-Smith T, Croul S, Adeniyi A, Rybicka K, Morgello S, Khalili K, Rappaport J.  Macrophage/microglial accumulation and proliferating cell nuclear antigen expression in the central nervous system in human immunodeficiency virus encephalopathy. Am J Pathol 2004, 164:2089-2099.

Murray J, Morgello S. Polyomaviruses and central nervous system lymphomas. Neurology 2004, 63(7):1299-1301.

Sacktor N, Haughey N, Cutler R, Tamara A, Turchan J, Pardo C, Vargas D, Nath A. Novel markers of oxidative stress in actively progressive HIV dementia. J Neuroimmunol 2004, 157:176-184.

Garden GW, Guo W, Jayadev S, Tun C, Balcaitis S, Choi J, Montine TJ, Möller T, Morrison R. HIV associated neurodegeneration requires p53 in neurons and microglia. The FASEB Journal 2004, 18:1141-1143. Full online version at

Hsu K, Seharaseyon J, Dong P, Bour S, Marbán E. Mutual functional destruction of HIV-1 Vpu and host TASK-1 channel. Molecular Cell 2004, 14:259-267. (supplied via NDRI).

Wang Z, Trillo-Pazos G, Kim SY, Canki M, Morgello S, Sharer LR, Gelbard HA, Su ZZ, Kang DC, Brooks AL, Fisher PB, Volsky DJ. Effects of human immunodeficiency virus type 1 on astrocyte gene expression and function: potential role in neuropathogenesis. J Neurovirol 2004, 10 Suppl 1:25-32.

Kolson DL, Sabnekar P, Baybis M, Crino PB. Gene expression in TUNEL-positive neurons in human immunodeficiency virus-infected brain. J Neurovirol 2004, 10 Suppl 1:102-107.

Good PF, Alapat D, Hsu A, Chu C, Perl D, Wen X, Burstein DE, Kohtz DS. A role for semaphorin 3A signaling in the degeneration of hippocampal neurons during Alzheimer’s disease. J Neurochemistry 2004, 91:716-736.

Cosenza MA, Zhao ML, Lee SC. HIV-1 expression protects macrophages and microglia from apoptotic death. Neuropathol Appl Neurobiol 2004, 30:478-490.

Morgello S. The Nervous System and HCV. Seminars in Liver Disease 2005, 25(1):118-121.

Estanislao LB, Morgello S, Simpson DM. Peripheral neuropathies associated with HIV and Hepatitis C Co-infection. AIDS 2005, 19 (suppl 3):S135-S139.

Koralnik IJ, Wüthrich C, Dang X, Rottnek  M, Gurtman A, Simpson D, Morgello S.  JC virus granule cell neuronopathy:  a novel syndrome distinct from PML. Ann Neurol 2005, 57:576-580.

Morgello S, Estanislao L, Ryan E, Gerits P, Simpson D, Verma S, DiRocco A, Sharp V, and the Manhattan HIV Brain Bank. Effects of hepatic function and hepatitis C virus on the nervous system assessment ofaAdvanced-stage, HIV-infected individuals. AIDS 2005, 19 (suppl 3):S116-S122.

Rempel HC, Pulliam L. HIV-1 tat inhibits neprilysin and elevates amyloid beta. AIDS 2005, 19:127-135.

Ryan EL, Baird R, Rivera-Mindt M, Byrd D, Monzones J, Morgello S. Neuropsychological impairment in racial/ethnic minorities with HIV infection and low literacy levels: Effects of education and reading level in participant characterization. Journal of the International Neuropsychological Society 2005, 11:889-898.

Morgello S, Holzer III CE, Ryan E, Young C, Naseer M, Steven A. Castellon SA, Frol AB, Atkinson JH, Gelman BB, Grant I, Singer EJ. Inter-rater reliability of the Psychiatric Research Interview for Substance and Mental Disorders in an HIV-infected cohort: Experience of the National NeuroAIDS Tissue Consortium. International Journal of Methods in Psychiatric Research 2006, 15(3):131-138.

Eljaschewitsch E, Witting A, Mawrin C, Lee T, Schmidt PM, Wolf S, Hoertnagl H, Raine CS, Schneider-Stock R, Nitsch R, Ullrich O. The endocannabinoid anandamide protects neurons during CNS inflammation by induction of MKP-1 in microglial cells. Neuron 2006, 49:67-79.

Shah M, Smit TK, Morgello S, Tourtellotte, Gelman B, Brew BJ, Saksena NK. Env gp120 sequence analysis of HIV type 1 strains from diverse areas of the brain shows preponderance of CCR5 usage. AIDS Res Hum Retroviruses 2006, 22(2):177-181.

Wüthrich C, Kesari S, Kim W-K, Williams K, Gelman R, Elmeric D, DeGirolami U, Joseph JT, Hedley-White T, Koralnik IJ. Characterization of lymphocytic infiltrates in progressive multifocal leukoencephalopathy: Co-localization of CD8+ T cells with JCV-infected glial cells. J Neurovirol 2006, 12:116-128.

Persidsky Y, Hellman D, Haorah J, Zelivyanskaya M, Persidsky R, Weber GA, Shimokawa H, Kabuchi K, Ikezu T. Rho-mediated regulation of tight junctions during monocyte migration across the blood-brain barrier in HIV-1 encephalitis (HIVE). Blood 2006, 107:4770-4780.

Wheeler EDA, Achim CL, Ayyavoo V. Immunodetection of human immunodeficiency virus type 1 (HIV-1) Vpr in brain tissue of HIV-1 encephalitic patients. J Neurovirology 2006, 12:200-210.

Cosenza-Nashat M, Kim M-O, Zhao M-L, Suh H-S, Lee SC. CD45 isoform expression in microglia and inflammatory cells in HIV-1 encephalitis. Brain Pathology 2006, 16:256-265.

Rosati A, Leone A, delValle L, Amini S, Khalili K, Turco MC. Evidence for BAG3 modulation of HIV-1 gene transcription. J Cellular Physiology 2006, 210:676-683.

Kaniowska D, Kaminski R, Amini S, Radhakrishnan S, Rappaport J, Johnson E, Khalili K, delValle L, Darbinyan A. Cross-interaction between JC virus agnoprotein and human immunodeficiency virus type 1 (HIV-1) tat modulates transcription of the HIV-1 long terminal repeat in glial cells. J Virology 2006, 80(18):9288-9299.

Aprea S, delValle L, Mameli G, Sawaya BE, Khalili K, Peruzzi F. Tubulin-mediated binding of human immunodeficiency virus-1 tat to the sytoskeleton causes proteasomal dependent degradation of microtubule-associated protein 2 and neuronal damage. J Neuroscience 2006, 26(15):4054-4062.

Chauhan A, Hahn S, Gartner S, Pardo CA, Netesan SK, McArthur J, Nath A. Molecular programming of endothelin-1 in HIV-infected brain:  Role of tat in up-regulation of ET-1 and its inhibition by statins. The FASEB Journal 2006, epub 12/28/2006. 2007, 21:000-000.

Kim WK, Alvarez X, Fisher J, Bronfin B, Westmoreland S, McLaurin J, Williams K. CD163 identifies perivascular macrophages in normal and viral encephalitic brains and potential precursors to perivascular macrophages in blood. Am J Pathol 2006, 168:822-834.

Pina-Oviedo S, Urbanska K, Radhakrishnan S, Sweet T, Reiss K, Khalili K, DelValle L. Effects of JC virus infection on anti-apoptotic protein surviving in progressive multifocal leukoencephalopathy. Am J Pathol 2007, 170:1291-1304.

Verma S, Cikurel K, Koralnik I, Morgello S, Cunningham-Rundles C, Weinstein Z, Bergmann C, Simpson DM. Mirtazapine in progressive multifocal leukoencephalopathy associated with polycythemia vera. J Infect Dis 2007, 196:709-711.

Cosenza-Nashat M, Zhao M-L, Marshall HD, Si Q, Morgello S, Lee SC. HIV-1 infection inhibits GM-CSF-induced microglial proliferation. J Neurovirol 2007, 13(6):536-548.

Kumar AM, Borodowsky I, Fernandez B, Gonzalez L, Kumar M. Human immunodeficiency virus type 1 RNA levels in different regions of human brain: Quantification using real-time reverse transcriptase-polymerase chain reaction. J Neurovirol 2007, 13:210-224.

Hahn K, Robinson B, Anderson C, Li W, Pardo C, Morgello S, Simpson D, Nath A. Differential effects of HIV infected macrophages on dorsal root ganglia neurons and axons. Experimental Neurology 2008, 210(1):30-40. PMCID: PMC2270478

Heinzen EL, Ge D, Cronin KD, Maia JM, Shianna KV, Gabriel WN, Welsh-Bohmer KA, Hulette CM, Denny TN, Goldstein DB. Tissue-specific genetic control of splicing: Implications for the study of complex trains. PLoS Biol 2008, 6(12):e1 (e1000001.doc10.1371/journal.pbio.1000001). PMCID:  PMC2605930

Murray J, Fishman SL, Ryan E, Eng FJ, Walewski JL, Branch AD, Morgello S. Clinicopathologic correlates of hepatitis C virus in brain: A pilot study. J Neurovirol 2008, 14:17-27. PMCID: PMC18300072

Ryan E, Byrd D, Rivera-Mindt M, Morgello S. Understanding the neuropsychological profile of HIV+ participants with low literacy: Role of the general ability measure for adults (GAMA). Clin Neuropsychol 2008, 22:1018-1034. PMCID: PMC18609327

Fishman SL, Murray J, Eng FJ, Walewski JL, Morgello S, Branch AD. Molecular and bioinformatics evidence of hepatitis C virus evolution in brain. J Infect Dis 2008, 197:597-607. PMCID: PMC18275278

Eugenin EA, Morgello S, Klotman ME, Mosoian A, Lento PA, Berman JW, Schecter AD.  HIV infects human arterial smooth muscle cells in vivo and in vitro: Implications for the pathogenesis of HIV-mediated vascular disease. Am J Pathol 2008, 172(4):1100-1111. PMCID: PMC2276423

Rivera-Mindt M, Byrd D, Ryan E, Robbins R, Monzones J, Arentoff A, Kubo-Germano K, Henninger D, Morgello S. Characterization and sociocultural predictors of neuropsychological test performance in HIV+ Hispanic individuals. Cultural Diversity and Ethnic Minority Psychology 2008, 14(4):315-325. PMCID: PMC18954167

Chaudhuri A, Yang B, Gendelman HE, Persidsky Y, Kanmogne GD. STAT1 signaling modulates HIV-1-induced inflammatory responses and leukocyte transmigration across the blood-brain barrier. Blood 2008, 111:2062-2072. PMCID: PMC2234049

Zheng JC, Huang Y, Tang K, Cui M, Niemann D, Lopez A, Morgello S, Chen S. HIV-1-infected and/or immune-activated macrophages regulate astrocyte CXCL8 production through IL-1B and TNF-a: Involvement of mitogen-activated protein kinase and protein kinase R. Journal of Neuroimmunology 2008, 200(1-2):100-110. PMCID: PMC2596956

Robinson-Papp J, Byrd D, Rivera Mindt M, Oden NL, Simpson DM, Morgello S, for the Manhattan HIV Brain Bank. Motor function and HIV-associated cognitive impairment in a HAART era cohort.  Archives of Neurology 2008, 65(8):1096-1101. PMCID: PMC18695060

Wu HS, Murray J, Morgello S. Segmentation of brain immunohistochemistry images using clustering of linear centroids and regional shapes. Journal of Imaging Science and Technology 2008, 52(4):040502-1 – 040502-11. PMID: 19756243, PMCID: PMC2743023

Gonzalez-Maeso J, Ang RL, Yuen T, Chan P, Weisstaub NV, Lopez-Gimenez JF, Zhou M, Okawa Y, Callado LF, Milligan G, Gingrich JA, Filizola M, Meana JJ, Sealfon SC. Identification of a serotonin/glutamate receptor complex implicated in psychosis. Nature 2008, 452(6):93-97. PMCID:  PMC2743172

Ancuta P, Kamat A, Kunstman KJ, Kim EY, Autissier P, Wurcel A, Zaman T, Stone D, Mefford M, Morgello S, Singer EJ, Wolinsky SM, Gabuzda D. Microbial translocation is associated with increased monocyte activation and dementia in AIDS patients. PLoS ONE 2008, 3:e2516. PMCID: PMC2424175

Burdo TH, Ellis RJ, Fox HS. Osteopontin is increased in HIV-associated dementia. JID 2008, 198:715-22. PMID: 18616394, PMCID:  PMC2587027

Douglas SD, Lynch KG, Lai JP. Neurokinin-1 receptor mRNA expression differences in brains of HIV-infected individuals. J Neurological Sci 2008, 272:174-177. PMCID: PMC2551749

Moll NM, Rietsch AM, Ransohoff AJ, Cossoy MB, Huang D, Eichler FS, Trapp BD, Ransohoff RM.  Cortical demyelination in PML and MS: Similarities and differences. Neurology 2008, 70:336-343. PMID: 17914063

Moody AL, Morgello S, Gerits P, Byrd DA. Vulnerabilities and caregiving in an ethnically diverse HIV-infected population. AIDS and Behavior 2009, 13:337-347. PMCID: PMC3815540

Yuferov V, Ji F, Nielsen DA, Levran O, Ho A, Morgello S, Shi R, Ott J, Kreek MJ. A functional haplotype implicated in vulnerability to develop cocaine dependence is associated with reduced PDYN expression in human brain. Neuropsychopharmacology 2009, 34(5):1185-1197. PMCID:  PMC18923396

Wyatt CM, Morgello S, Katz-Malamed R, Wei C, Klotman ME, Klotman PE, D’Agati VD. Acquired Immunodeficiency Syndrome and the spectrum of kidney disease in the era of antiretroviral therapy: Data from the Manhattan HIV Brain Bank. Kidney International 2009, 75:428-434. PMCID:  PMC19052538

Robinson-Papp J, Gonzalez-Duarte A, Simpson DM, Rivera-Mindt M, Morgello S for the MHBB.  The roles of ethnicity and antiretrovirals in HIV-associated polyneuropathy: A pilot study. J AIDS 2009, 51(5):569-573. PMCID: PMC19521250

Wilkinson J, Radkowski M, Laskus T. Hepatitis C Virus neuroinvasion: Identification of infected cells. J Virol 2009, 83:1312-1319. PMCID: PMC19019968

Wüthrich C, Cheng YM, Joseph JT, Kesari S, Beckwith C, Stopa E, Bell JE, Koralnik I. Frequent infection of cerebellar granule cell neurons by polyomavirus JC in progressive multifocal leukoencephalopathy. J Neuropathol Exp Neurol 2009, 68(1):15-25. PMCID: PMC19104450

Khanlou N, Moore DJ, Chana G, Cherner M, Lazzaretto D, Dawes S, Grant I, Masliah E, Everall IP, HNRC Group. Increased frequency of alpha-synuclein in the substantia nigra in human immunodeficiency virus infection. J Neurovirol 2009, 15:131-138. PMCID: PMC19115126

Cosenza-Nashat M, Zhao ML, Suh HS, Morgan J, Natividad R, Morgello S, Lee SC.  Expression of the translocator protein of 18kDa by microglia, macrophages and astrocytes based on immunohistochemical localization in abnormal human brain. Neuropathol Appl Neurobiol 2009, 35(3):306-328. PMCID: PMC2693902

Paragas N, Nickolas T, Wyatt C, Forster C, Sise M, Morgello S, Jagla B, Buchen C, Stella P, Sanna-Cherchi S, Carnevali ML, Mattei S, Bovino A, Argentiero L, Magnano A, Devarajan P, Schmidt-Ott KM, Allegri L, Klotman P, D'Agati V, Gharavi A, Barasch J. Urinary NGAL marks tubular disease in HIVAN. J Amer Soc Nephrology 2009, 20(8):1687-1692. PMCID: PMC19628667

Stettner MR, Nance JA, Wright C, Kinoshita Y, Kim WK, Morgello S, Rappaport J, Khalili K, Gordon J, Johnson EM. SMAD proteins of oligodendroglial cells regulate transcription of JC virus early and late genes coordinately with the tat protein of human immunodeficiency virus type 1. J Gen Virol 2009, 90(Pt 8):2005-2014. PMCID:  PMC19420158

Everall I, Vaida F, Khanlou N, Lazzaretto D, Achim C, Letendre S, Moore D, Ellis R, Cherner M, Gelman B, Morgello S, Singer E, Grant I, Masliah E, for the NNTC. Clinicopathologic correlates of HIV in the era of antiretroviral therapy. J Neurovirol 2009, 15:360-370. PMCID: PMC20175693

Kumar AM, Fernandez JB, Singer EJ, Commins D, Waldrop-Valverde D, Ownby RL, Kumar M.  Human immunodeficiency virus type 1 in the central nervous system leads to decreased dopamine in different regions of postmortem human brains. J Neurovirol 2009, 15:257-274. PMCID:  PMC19499455

Weiss JJ, Morgello S. Psychiatric management of HIV/HCV-co-infected patients beginning treatment for hepatitis C virus infection: Survey of provider practices. Gen Hosp Psychiatr 2009, 31:531-537. PMCID: PMC19892211

Tan CS, Dezube BJ, Bhargava P, Autissier P, Wüthrich C, Miller J, Koralnik IJ. Detection of JC virus DNA and proteins in the bone marrow of HIV-positive and HIV-negative patients: Implications for viral latency and neurotropic transformation. J Infect Dis 2009, 199:881-888. PMCID:  PMC19434914

Clifford DB, Fagan AM, Holtzman DM, Morris JC, Teshome M, Shah AR, Kauwe JSK. CSF biomarkers of Alzheimer disease in HIV-associated neurologic disease. Neurology 2009, 73:1982-1987. PMCID:  PMC2790234

Levine AJ, Singer EJ, Sinsheimer JS, Hinkin CH, Papp J, Dandekar S, Giovanelli A, Shapshak P.  CCL3 genotype and current depression increase risk of HIV-associated dementia. Neurobehavioral HIV Medicine 2009, 1:1-7. PMCID: PMC2923399

Gonzalez-Duarte A, Sullivan S, Sips GJ, Naidich T, Kleinman G, Murray J, Morgello S, Germano I, Mullen M, Simpson DM. Inflammatory pseudotumor associated with HIV, JCV an immune reconstitution syndrome. Neurology 2009, 72(3):289-290. PMCID: PMC19153378

Roberts TK, Eugenin EA, Morgello S, Clements JE, Zink MC, BermanJW. PrPC, the cellular isoform of the human prion protein, is a novel niomarker of HIV-asssociated neurocognitive impairment and mediates Neuroinflammation. Am J Pathology 2010, 177(4):1848-1860. PMCID:  PMC2947280

King JE, Eugenin EA, Hazleton JE, Morgello S, Berman JW. Mechanisms of HIV-tat induced phosphorylation of NMDA receptor subunit 2A in human primary neurons: Implications for neuroAIDS pathogenesis. Am J Pathology 2010, 176(6):2819-2830. PMCID: PMC2877843

Tan CS, Ellis LC, Wuthrich C, Ngo L, Broge TA, Saint-Aubyn J, Miller JS, Koralnik IJ. JC virus latency in the brain and extraneural organs of patients with and without progressive multifocal leukoencephalopathy. J Virol 2010, 84(18): 9200-9209. PMCID: PMC2937633

Suh HS, Cosenza-Nashat M, Choi N, Zhao ML, Li JF, Pollard JW, Jirtle RL, Goldstein H, Lee SC.  Insulin-like growth factor 2 receptor is an IFNgama-inducible microglial protein that facilitates intracellular HIV replication: Implications for HIV-induced neurocognitive disorders. Am J Pathol 2010, 177(5):2446-2458. PMCID:  PMC2966802

Yelamanchili SV, Chaudhuri AD, Chen LN, Xiong H, Fox HS. MicroRNA-21 dysregulates the expression of MEF2C in neurons in monkey and human SIV/HIV neurological disease. Cell Death Dis 2010, Sept 23, 1, e77. PMCID: PMC3002786

Pitcher J, Shimizu S, Burbassi S, Meucci O. Disruption of neuronal CXCR4 function by opioids:  Preliminary evidence of Ferritin heavy chain as a potential etiological agent in neuroAIDS. J Neuroimmunol 2010, 224:66-71. PMCID: PMC2910242

Wang Y, Shyam N, Ting JH, Akay C, Lindl KA, Jordon-Sciutto KL. E2F1 localizes predominantly to neuronal cytoplasm and fails to induce expression of its transcriptional targets in human immunodeficiency virus-induced neuronal damage. Neurosci Lett 2010 Jul 26, 479(2):97-101. PMCID:  PMC2902623

Dhillon NK, Li F, Xue B, Tawfik O, Morgello S, Buch S, Ladner AO. Effect of cocaine on HIV-mediated pulmonary endothelial and smooth muscle dysfunction. Am J Resp Cell and Mol Biol 2011, 45(1):40-52. PMCID: PMC3145070

Lehmann HC, Chen W, Borzan J, Mankowski JL, Hoke A. Mitochondrial dysfunction in distal axons contributes to human immunodeficiency virus sensory neuropathy. Ann Neurol 2011, 69:100-110. PMCID: PMC3051401

Cosenza-Nashat M, Bauman A, Zhao ML, Morgello S, Suh HS, Lee SC. Cannabinoid receptor expression in HIV encephalitis and HIV-associated neuropathologic comorbidities. Neuropathol Appl Neurobiol 2011, 37(5):464-483. PMCID: PMC3135748

Wu HS, Murray J, Morgello S, Fiel MI, Schiano T, Kalir T, Deligdisch L, Joan Gil J. Restoration of distorted colour microscopic images from transverse chromatic aberration of imperfect lenses.  J Microscopy 2011, 241(2):125-131. PMCID: PMC3807600

Lyons JL, Uno H, Ancuta P, Kamat A, Moore DJ, Singer EJ, Morgello S, Gabuzda D. Plasma sCD14 is a biomarker associated with impaired neurocognitive test performance in attention and learning domains in HIV infection.  J AIDS 2011, 57(5):371-379. PMCID: PMC3159710

Yao H, Kee-Jun K, Duan M, Hayashi T, Guo M, Morgello S, Prat A, Wang J, Su TP, Buch S. Cocaine hijacks sigma-1 receptor to initiate induction of ALCAM: Implication for increased monocyte adhesion and migration in the central nervous system. J Neurosci 2011, 31(16):5942-5955.  PMCID: PMC3410749

Borjabad A, Morgello S, Chao W, Kim SY, Brooks AI, Murray J, Potash MJ, Volsky DJ. Significant effects of Antiretroviral therapy on global gene expression in brain tissues of patients with HIV-1-associated neurocognitive disorders. PLoS Pathogens 2011, 7(9): e1002213. doi:10.1371/journal.ppat.1002213. PMCID: PMC3164642

Brown A, Islam T, Adams R, Nerle S, Kamara M, Eger C, Marder K, Cohen B, Schifitto G, McArthur JC, Sacktor N, Pardo C. Osteopontin enhances HIV replication and is increased in the brain and cerebrospinal fluid of HIV-infected individuals. J Neurovirol 2011, 17:382-392. PMCID: PMC3331788

Soulas C, Conerly C, Kim WK, Burdo TH, Alvarez X, Lackner AA, Williams KC. Recently infiltrating MAC387+ monocytes/macrophages. A third macrophage population involved in SIV and HIV encephalitic lesion formation. Am J Pathol 2011, 178(5):2121-2135. PMCID: PMC3081227

Shimizu S, Brown M, Sengupta R, Penfold ME, Meucci O. CXCR7 protein expression in human adult brain and differentiated neurons. PLoS One 2011;6(5):e20690. Epub 2011 May 31. PMCID: PMC3105114

Yuferov V, Nielsen DA, Levran O, Randesi M, Hamon S, Ho A, Morgello S, Kreek MJ. Tissue-specific DNA methylation of the human prodynorphin gene in postmortem brain tissues and PBMCs. Pharmacogenetics and Genomics 2011, 21(4):185-196. PMCID: PMC3017726

Langford D, Baron D, Joy J, Del Valle L, Shack J. Contributions of HIV infection in the hypothalamus and substance abuse/use to HPT dysregulation. Psychoneuroendocrinology 2011, 36:710-719. PMCID: PMC3090485

Kamat A, Misra V, Cassol E, Ancuta P, Yan Z, Li C, Morgello S, Gabuzda D. A plasma biomarker signature of immune activation in HIV patients on antiretroviral therapy. Plos ONE 2012, 7(2):e30881. PMID 22363505, PMCID: PMC3281899

Fletcher NF, Wilson GK, Murray J, Hu K, Reynolds GM, Stamataki Z, Meredith LW, Lewis AP, Rowe IA, Luo G, Lopez-Ramirez MA, Baumert TF, Weksler B, Couraud PO, Romero IA, Jopling CL, Morgello S, Balfe P, McKeating JA. Hepatitis C virus infectis endothelial cells of the blood-brain barrier. Gastroenterology 2012, 142(3):634-643. PMCID: PMC3801216

Wuthrich C, Koralnik IJ. Frequent infection of cortical neurons by JC virus in patients with progressive multifocal leukoencephalopathy. J Neuropathol Exp Neurol 2012, 71(1):54-65. PMCID: PMC3246306

Kamat A, Lyons JL, Misra V, Uno H, Morgello S, Singer EJ, Gabuzda D. Monocyte activation markers in cerebrospinal fluid associated with impaired neurocognitive testing in advanced HIV infection. JAIDS 2012, 60:234-243. PMCID: PMC3383928

Dang X, Vidal JE, Penalva de Oliveira AC, Simpson D, Morgello S, Hecht JH, Ngo LH, Koralnik IJ. JC virus Granule Cell Neuronopathy is caused by VP1 c-terminus mutants J Gen Virol 2012, 93(Pt 1):175-183. PMCID:  PMC3352331

Robinson-Papp J, Gelman BB, Grant I, Singer E, Gensler G, Morgello S for the National NeuroAIDS Tissue Consortium. Substance abuse increases the risk of neuropathy in an HIV-infected cohort. Muscle and Nerve 2012, 45(4):471-476. PMCID: PMC3313074

Fellows RP, Byrd DA, Elliott K, Robinson-Papp J, Rivera-Mindt M, Morgello S, for the Manhattan HIV Brain Bank. Distal sensory polyneuropathy is associated with neuropsychological test performance among persons with HIV. J Int Neuropsychol Soc 2012, 18(5):898-907. PMCID: PMC3571681

Akay C, Lindl KA, Shyam N, Nabet B, Goenaga-Vazquez Y, Ruzbarsky J, Wang Y, Kolson DL, Jordan-Sciutto KL. Activation status of integrated stress response pathways in neurons and astrocytes of HIV-associated neurocognitive disorders (HAND) cortex. Neuropathol Appl Neurobiol 2012, 38:175-200. PMCID: PMC3708539

Robinson-Papp J, Elliott K, Pizzirusso M, Morgello S, Autonomic neuropathy in HIV: A case report and review of potential symptoms in an advanced-stage, HIV cohort. World Journal of AIDS 2012, 2:265-269.

Bachis A, Avdoshina V, Zecca L, Parsadanian M, Mocchetti I. Human immunodeficiency virus type 1 alters brain-derived neurotrophic factor processing in neurons. J Neurosci 2012, 32(28):9477-9484. PMCID:  PMC3408006

Kurita M, Holloway T, Garcia-Bea A, Kozlenkov A, Friedman AK, Moreno JL, Heshmati M, Golden SA, Kennedy PJ, Takahashi N, Dietz DM, Mocci G, Gabilondo AM, Hanks J, Umail A, Callado LF, Gallitano AL, Neve RL, Shen L, Buxbaum JD, Han MH, Nestler EJ, Meana JJ, Russo SJ, Gonzalez-Maeso, J. HDAC2 regulates atypical antipsychotic responses through the modulation of mGlu2 promoter activity. Nature Neuroscience 2012, 15(9):1245-1254. PMCID: PMC3431440

Dever SM, Xu R, Fitting S, Knapp PE, Hauser KF. Differential expression and HIV-1 regulation of u-opioid receptor splice variants across human central nervous system cell types. J Neurovirol 2012, 18(3):181-190 PMCID: PMC3731452

Arentoft A, Byrd D, Robbins RN, Monzones J, Miranda C, Rosario A, Coulehan K, Fuentes A, Kubo-Germano K, D’Aquila E, Sheynin J, Fraser F, Morgello S, Rivera Mindt M. Multidimensional effects of acculturation on English-language neuropsychological test performance among HIV+ Caribbean Latinas/os. Journal of Clinical and Experimental Neuropsychology 2012, 34(8):814-825. PMCID: PMC3434263

Robbins RN, D’Aquila E, Morgello S, Byrd D, Remien RH, Rivera-Mindt M. Cultural influences on antiretroviral therapy adherence among HIV-infected Puerto Ricans. J Assoc Nurses AIDS Care 2012, 23(6):531-538. PMCID: PMC3406236

Robinson-Papp J, Elliott K, Simpson DM, Morgello S, for the Manhattan HIV Brain Bank.  Problematic prescription opioid use in an HIV-infected cohort: The importance of universal toxicology testing. J AIDS 2012, 61(2):187-193. PMCID: PMC3458135

Byrd D, Murray J, Safdieh G, Morgello S.  Impact of opiate addiction on neuroinflammation in HIV. J Neurovirol 2012, 18:364-373. PMCID: PMC3573366

Jacobs MM, Okvist S, HorvathM, Keller E, Bannon MJ, Morgello S, Hurd YL. Dopamine receptor D1 and post-synaptic density gene variants associate with opiate abuse and striatal expression levels. Molecular Psychiatry 2012, Oct 9 doi: 10.1038/mp.2012.140. PMCID: PMC3637428

Gelman BB, Chen T, Lisinicchia JG, Soukup VM, Carmical JR, Starkey JM, Masliah E, Commins DL, Brandt D, Grant I, Singer EJ, Levine AJ, Miller J, Winkler JM, Fox HS, Luxon BA, Morgello S, and the National NeuroAIDS Tissue Consortium. The National NeuroAIDS Tissue Consortium brain gene array: Two types of HIV-associated neurocognitive impairment. PloS ONE 2012, 7(9):e46178. Doi: 10.1371/journal.pone.0046178. PMCID:  PMC3458860

Soontornniyomkij V, Moore DJ, Gouaux B, Soontornniyomkij B, Tatro ET, Umlauf A, Masliah E, Levine AJ, Singer EJ, Vinters HV, Gelman BB, Morgello S, Cherner M, Grant I, Achim CL. Cerebral -amyloid deposition predicts HIV-associated neurocognitive disorders in APOE 4 carriers.  AIDS 2012, 26(18):2327-2335. PMCID: PMC3576852

Gelman BB, Lisinicchia JG, Morgello S, Masliah E, Commins D, Achim CL, Fox HS, Kolson DL, Grant I, Singer E, Yiannoutsos CT, Sherman S, Gensler G, Moore DJ, Chen T, Soukup VM.  Neurovirological correlation with HIV-associated neurocognitive disorders and encephalitis in a HAART-era cohort. J AIDS 2013, 62:487-495. PMCID: PMC3664102

Tarassishin L, Bauman A, Suh HS, Lee SC. Anti-viral and anti-inflammatory mechanisms of the innate immune transcription factor interferon regulatory factor 3: Relevance to human CNS diseases. J Neuroimmune Pharmacol 2013, 8(1):132-144. PMID: 22684309

Fellows RP, Byrd DA, Morgello S, for the Manhattan HIV Brain Bank. Major depressive disorder, cognitive symptoms, and neuropsychological performance among ethnically diverse HIV+ men and women. J Int Neuropsychol Soc 2013, 19(2):216-225. PMCID: PMC3785228

Yuferov V, Ho A, Morgello S, Yang Y, Ott J, Kreek MJ. Expression of ephrin receptors and ligands in postmortem brains of HIV-infected subjects with and without cognitive impairment. J Neuroimmune Pharmacol 2013, 8(1):333-344. PMCID: PMC3587720

Byrd DA, Robinson-Papp J, Rivera-Mindt M, Mintz L, Elliott K, Lighty Q, Morgello S for the MHBB.  Isolating cognitive and neurologic HIV effects in substance-dependent, confounded cohorts: A pilot study. J Int Neuropsychol Soc 2013, 19(4):463-473. PMCID: PMC3815532

Levine AJ, Miller JA, Shapshak P, Gelman B, Singer EJ, Hinkin CH, Commins D, Morgello S, Grant I, Horvath S. Systems analysis of brain gene expression: Mechanisms for HIV-associated neurocognitive impairment and common pathways with Alzheimer’s disease.  BMC Medical Genomics 2013, 6:4  doi:10.1186/1755-8794-6-4. PMCID: PMC3626801

Cassol E, Misra V, Holman A, Kamat A, Morgello S, Gabuzda D. Plasma metabolomics identifies lipid abnormalities linked to markers of inflammation, microbial translocation, and hepatic function in HIV patients receiving protease inhibitors. BMC Infectious Diseases 2013, May 4;13:203. doi: 10.1186/1471-2334-13-203. PMCID: PMC3655873

Williams DW, Calderon TM, Lopez L, Carvallo L, Gaskill PJ, Eugenin EA, Morgello S, Berman JW. Mechanisms of HIV entry into the CNS: Increased sensitivity of HIV infected CD14+CD16+ monocytes to CCL2 and key roles of CCR2, JAM-A, and ALCAM in Diapedesis. PLOS One 2013, 8(7):e69270. doi:10.1371/journal.pone.0069270. PMCID: PMC3724935

Panos SE, Hinkin CH, Singer EJ, Thames AD, Patel S, Sinsheimer JS, Del Re AC, Gelman B, Morgello S, Moore DJ, Levine AJ. Apolipoprotein-E genotype and human immunodeficiency virus-associated neurocognitive disorder: Modulating effects of older age and disease severity. Neurobehavioral HIV Medicine 2013, 5: 11-22. 

Lawhorn C, Yuferov V, Randesi M, Ho A, Morgello S, Kreek MJ, Levran O. Genetic diversity and linkage disequilibrium in the chemokine receptor CCR2-CCR5 region among individuals and populations. Cytokine 2013, 64(2):571-576. PMCID: PMC3806048

Orellana JA, Saez JC, Bennett MVL, Berman JW, Morgello S, Eugenin E. HIV increased the release of dickkopf-1 (DKK1) protein from human astrocytes by a Cx43 hemichannel-dependent mechanism. J Neurochem 2013, Oct 18. doi: 10.111/jnc.12492 PMCID: PMC4340662

Jacobs MM, Murray J, Byrd DA, Hurd YL, Morgello S. HIV-related cognitive impairment shows bi-directional association with dopamine receptor DRD1 and DRD2 polymorphisms in substance-dependent and substance-independent populations. J Neurovirol 2013, 19:495-504. PMCID: PMC3856629

Cassol E, Misra V, Morgello S, Gabuzda D. Applications and limitations of inflammatory biomarkers for studies on neurocognitive impairment in HIV infection. J Neuroimmune Pharmacol 2013, 8(5):1087-1097. PMCID: PMC3889222

Megra B, Eugenin E, Roberts T, Morgello S, Berman JW. Protease resistant protein cellular isoform (PrP(c)) as a biomarker: Clues into the pathogenesis of HAND. J Neuroimmune Pharmacol 2013 8(5):1159-1166. PMCID: PMC3797864

Pacifici M, Delbue S, Ferrante P, Jeansonne D, Kadri F, Nelson S, Velasco-Gonzalez C, Zabaleta J, Peruzzi F. Cerebrospinal fluid miRNA profile in HIV-encephalitis. J Cell Physiol 2013, 228(5):1070-1075. PMCID:  PMC3760673

Yuferov V, Butelman ER, Ho A, Morgello S, Kreek MJ. Neurocognitive and neuroinflammatory correlates of PDYN and OPRK1 mRNA expression in the anterior cingulate in postmortem brain of HIV-infected subjects. J Neuroinflammation 2014, Jan 9; 11(1):5 (epub ahead of print). PMCID:  PMC3896676

Rivera MIndt M, Miranda C, Arentoft A, Byrd D, Renteria MA, Fuentes A, Arias F, Monzones J, Rosario A, Morgello S. Aging and HIV/AIDS: Neurocognitive implications for older HIV+ Latina/o adults. Behavioral Medicine 2014, 40:116-123. PMID: 25090364

Gutierrez J, Rosoklija G, Murray J, Chon C, Elkind MSV, Goldman J, Honig L, Dwork AJ, Morgello S, Marshall RS. A quantitative perspective to the study of brain arterial remodeling of donors with and without HIV in the Brain Arterial Remodeling Study (BARS). Frontiers Physiology 2014, 5:56. PMCID: PMC3928551

Robbins RN, Brown H, Ehlers A, Joska JA, Thomas KGF, Burgess R, Byrd D, Morgello, S. A smartphone app to screen for HIV-related neurocognitive impairment.  J Mobile Technology in Medicine 2014, 3(1):23-36. PMCID: PMC4029593

Cassol E, Misra V, Dutta A, Morgello S, Gabuzda D. CSF metabolomics reveals altered waste clearance and accelerated aging in HIV patients with neurocognitive impairment. AIDS 2014, 28(11):1579-1591. PMCID: PMC4086755

Gutierrez J, Goldman J, Elkind MSV, Dwork AJ, Morgello S, Marshall RS. Determinants of cerebrovascular remodeling: Do large brain arteries accommodate stenosis? Atherosclerosis 2014, 235(2):371-379. PMCID: PMC4121968

Tavazzi E, Morrison D, Sullivan P, Morgello S, Fischer T. Brain inflammation is a common feature of HIV-infected patients without HIV encephalitis or productive brain infection. Curr HIV Res 2014, 12(2):97-110. PMCID: PMC4152918

WIlliams DW, Veenstra M, Gaskill PJ, Morgello S, Calderon TM, Berman JW. Monocytes mediate HIV neuropathogenesis: Mechanisms that contribute to HIV associated neurocognitive. Curr HIV Res 2014, 12(2):85-96. PMCID: PMC4351961

Coulehan K, Byrd D, Arentoft A, Monzones J, Fuentes A, Fraser F, Rosario A, Morgello S, Rivera-Mindt M. The role of decision-making ability in HIV/AIDS: Impact on prospective memory. J Clin Exp Neuropsychol 2014 Aug 4:1-12 (epub ahead of print). PMID: 25089330

Fellows R, Byrd D, Morgello S. Effects of information processing speed on learning, memory, and executive functioning in people living with HIV/AIDS. J Clin Exp Neuropsychol 2014, Aug 11:1-12 (epub ahead of print). PMCID: PMC4338860

Fischer T, Wyatt CM, D'Agati VD, Croul S, McCourt L, Morgello S, Rappaport J. Mononuclear phagocyte accumulation in visceral tissue in HIV encephalitis: Evidence for increased monocyte/macrophage trafficking and altered differentiation. Curr HIV Res 2014, 12:12(3):201-212. PMCID: PMC4314220

Morgello S, Murray J, VanderElst S, Byrd D. HCV, but not HIV, is a risk factor for cerebral small vessel disease. Neurology: Neuroimmunology and Neuroinflammation 2014, Oct 9; 1(3):e36. doi: 10.1212/NXI.0000000000000036. PMCID: PMC4204233

Williams DW, Byrd D, Rubin LH, Anastos K, Morgello S, Berman JW. CCR2 on CD14+CD16+ monocytes is a biomarker of HIV associated neurocognitive disorders. Neurology: Neuroimmunology and Neuroinflammation 2014, Oct 9; 1(3):e36. doi: 10.1212/NXI.0000000000000036. PMCID: PMC4204222

Pitcher J, Abt A, Myers J, Han R, Snyder M, Graziano A, Festa L, Kutzler M, Garcia F, Gao WJ, Fischer-Smith T, Rappaport J, Meucci O. Neuronal ferritin heavy chain and drug abuse affect HIV-associated cognitive dysfunction. J Clin Invest 2014, 124(2):656-669. PMC ID:  PMC3904611

Dever SM, Costin BN, Xu R, El-Hage N, Balinang J, Samoshkin A, O'Brien MA, McRae M, Diatchenko L, Knapp PE, Hauser KF. Differential expression of the alternatively spliced OPRM1 isoform mu-opioid receptor-1K in HIV-infected individuals. AIDS 2014, 28(1):19-30. PMCID: PMC3939043

Zenon F, Segarra AC, Gonzalez M, Melendez LM. Cocaine potentiates cathepsin B secretion and neuronal apoptosis from HIV-infected macrophages. J Neuroimmune Pharmacol 2014, 9(5):703-715. PMCID: PMC4209444

Holder GE, McGary CM, Johnson EM, Zheng R, John VT, Sugimoto C, Kuroda MJ, Kim WK.  Expression of the mannose receptor CD206 in HIV and SIV encephalitis: A phenotypic switch of brain perivascular macrophages with virus infection. J neuroimmune pharmacol 2014, 9:716-726. PMCID: PMC4364002

Williams D, Anastos K, Morgello S, Berman J. JAM-A and ALCAM are therapeutic targets to inhibit diapedesis across the BBB of CD14+CD16+ monocytes in HIV infected individuals.  J Leukocyte Biol 2015, 97(2):401-412. PMCID: PMC4304417

Robinson-Papp J, Sharma S, Dhadwal N, Simpson DM, Morgello S. Optimizing measures of HIV-associated neuropathy. Muscle Nerve 2015, 51(1):56-64 PMCID: PMC4225193

Cassol E, Misra V, Morgello S, Kirk G, Mehta S, Gabuzda D. Altered monoamine and aculcarnitine metabolites in HIV-positive and HIV-negative subjects with depression. J AIDS 2015, 69:18-28. PMCID: PMC4562456

Gutierrez J, Elkind MSV, Virmani R, Goldman J, Honig L, Morgello S, Marshall RS. A pathological perspective on the natural history of cerebral atherosclerosis. Int J Stroke 2015, 10(7): 1074-1080. PMCID: PMC4583838

Thames AD, Briones MS, Mangpatay L, Martinez-Maza O, Singer EL, Hinkin CH, Morgello S, Gelman B, Moore DJ, London E, Heizerling K, Levine AJ. The role of CCL2 genotype and cerebrospinal fluid CCL2 in neurocognition among HIV-infected patients. AIDS 2015, 29(12):1483-1491. PMCID: PMC4573552

Gutierrez J, Goldman J, Dwork AJ, Elkind MSV, Marshall RS, Morgello S. Brain arterial remodeling contribution to non-embolic brain infarcts in patients with HIV. Neurology 2015, 85(13):1139-1145. PMCID: PMC4603890

Dever SM, Rodriguez M, Lapierre J, Costin BN, El-Hage N. Differing roles of autophagy in HIV-associated neurocognitive impairment and encephalitis with implications for morphine co-exposure. Frontiers in Microbiology 2015, doi: 10.3389/fmicb.2015.00653. PMCID:  PMC4491626

Zenon F, Cantres-Rosario Y, Adiga R, Gonzalez M, Rodriguez-Franco E, Langford D, Melendez LM.  HIV-infected microglia mediate cathepsin B-induced neurotoxicity. Journal of Neurovirology 2015, 21:544-558. PMCID:  PMC4618197

Olsen J, Fellows R, Rivera-Mindt M, Morgello S, Byrd D. Reading ability as an estimator of premorbid intelligence: Does it remain stable among ethnically diverse HIV+ adults? The Clinical Neuropsychologist 2015, 29(7):1034-1052. PMCID: PMC4738021

Fellows RP, Spahr NA, Byrd DA, Rivera-Mindt M, Morgello S, for the Manhattan HIV Brain Bank.  Psychological trauma exposure and co-morbid psychopathologies in HIV+ men and women.  Psychiatry Research 2015, 230(3):770-776. PMCID: PMC4801502

Arentoft A, Byrd D, Monzones J, Coulehan K, Fuentes A, Rosario A, Miranda C, Morgello S, Rivera Mindt M. Socioeconomic status and neuropsychological functioning: Associations in an ethnically diverse HIV+ cohort. The Clin Neuropsychol 2015, 29(2):232-254. PMCID: PMC4443910

Gutierrez J, Menshawy K, Gonzalez M, Elkind MSV, Marshall R, Dwork A, Morgello S. Brain large artery inflammation associated with human immunodeficiency virus and large artery remodeling. AIDS 2016, 30(3):415-423. PMID: 26765935

Gutierrez J, Honig LS, Elkind MSV, Mohr JP, Goldman JE, Dwork AJ, Morgello S, Marshall RS.  Brain arterial aging and its relationship to Alzheimer dementia. Neurology 2016, 86(16):1507-1515. PMCID: PMC4836884

Miranda C, Arce-Renteria M, Fuentes A, Coulehan K, Arentoft A, Byrd D, Rosario A, Monzones J, Morgello S, Rivera Mindt M. The relative utility of three English language dominance measures in predicting the neuropsychological performance of HIV+ bilingual Latino/a adults. Clin Neuropsychol 2016. Mar 3:1-16 (epub ahead of print) PMID: 26934820

Dever SM, Rodriguez M, El-Hage N. B-Adrenergic receptor gene expression in HIV-associate neurocognitive impairment and encephalitis: Implications for MOR-1K subcellular localization. J Neurovirol 2016, doi:10.1007/s13365-016-0464-1 PMID: 27400929