Publications

Our Mood and Anxiety Disorders Program team makes a substantial contribution to the body of research on mood and anxiety disorders by publishing in a wide variety of peer-reviewed journals. We contribute to both psychologically and physiologically focused publications.

Tawakol, A, Ishai, A, Takx, RA, Figueroa, AL, Ali, A, Kaiser, Y, Truong, QA, Solomon, CJ, Calcagno, C, Mani ,V, Tang, CY, Mulder, WJ, Murrough, JW, Hoffmann, U, Nahrendorf, M, Shin, LM, Fayad, ZA, Pitman, RK. (2017). Relation between resting amygdalar activity and cardiovascular events: a longitudinal and cohort study. The Lancet, Volume 389, Issue 10071, 25 February–3 March 2017, Pages 834–845

Van Dam NT, O'Connor D, Marcelle ET, Ho EJ, Cameron Craddock R, Tobe RH, Gabbay V, Hudziak JJ, Xavier Castellanos F, Leventhal BL, Milham MP. (2017). Data-Driven Phenotypic Categorization for Neurobiological Analyses: Beyond DSM-5 Labels. Biol Psychiatry. 2017 Mar 15;81(6):484-494. doi: 10.1016/j.biopsych.2016.06.027. PMID:27667698

McDonald AR, Muraskin J, Van Dam NT, Froehlich C, Puccio B, Pellman J, Bauer CC, Akeyson A, Breland MM, Calhoun VD, Carter S, Chang TP, Gessner C, Gianonne A, Giavasis S, Glass J, Homann S, King M, Kramer M, Landis D, Lieval A, Lisinski J, Mackay-Brandt A, Miller B, Panek L, Reed H, Santiago C, Schoell E, Sinnig R, Sital M, Taverna E, Tobe R, Trautman K, Varghese B, Walden L, Wang R, Waters AB, Wood DC, Castellanos FX, Leventhal B, Colcombe SJ, LaConte S, Milham MP, Craddock RC. (2017). The real-time fMRI neurofeedback based stratification of Default Network Regulation Neuroimaging data repository. Neuroimage. 2017 Feb 1;146:157-170. doi: 10.1016/j.neuroimage.2016.10.048. PMID: 27836708

Cassano, P, Petrie, SR, Hamblin, MR, Henderson, TA, Iosifescu, DV. (2016). Review of transcranial photobiomodulation for major depressive disorder: Targeting brain metabolism, inflammation, oxidative stress, and neurogenesis. Neurophotonics, 3, TK-31404. PMID: 26989758

Feder, A, Mota, N, Salim, R, Rodriguez, J, Singh, R, Schaffer, J, Schechter, CB, Cancelmo, LM, Bromet, EJ, Katz, CL, Reissman, DB, Ozbay, F, Kotov, R, Crane, M, Harrison, DJ, Herbert, R, Levin, SM, Luft, BJ, Moline, JM, Stellman, JM, Udasin, IG, Landrigan, PJ, Zvolensky, MJ, Yehuda, R, Southwick, SM, Pietrzak, RH. (2016). Risk, coping and PTSD symptom trajectories in World Trade Center responders. Journal of Psychiatric Research, 82, 68-79. PMID: 27468166

Friedman, AK, Juarez, B, Ku, SM, Zhang, H, Calizo, RC, Walsh, JJ, Chaudhury, D, Zhang, S, Hawkins, A, Dietz, DM, Murrough, JW, Ribadeneira, M, Wong, EH, Neve, RL, Han, MH. (2016). KCNQ channel openers reverse depressive symptoms via an active resilience mechanism. Nature Communications, 7, 11671. PMID: 27216573

Horn, SR, Charney, DS, Feder, A. (2016). Understanding resilience: New approaches for preventing and treating PTSD. Experimental Neurology, in press. PMID: 27417856      

Lener, MS, Kundu, P, Wong, E, Dewilde, KE, Tang, CY, Balchandani, P, Murrough, JW. (2016). Cortical abnormalities and association with symptom dimensions across the depressive spectrumJournal of Affective Disorders, 190, 529-536.

Murrough, JW, Abdallah, CG, Anticevic, A, Collins, KA, Geha, P, Averill, LA, Schwartz, J, Dewilde, KE, Averill, C, Jia-Wei Yang, G, Wong, E, Tang, CY, Krystal, JH, Iosifescu, DV, Charney, DS. (2016). Reduced global functional connectivity of the medial prefrontal cortex in major depressive disorder. Human Brain Mapping, 37, 3214-23. PMID: 27144347

Schwartz, J, Murrough, JW, Iosifescu, DV. (2016). Ketamine for treatment-resistant depression: Recent developments and clinical applications. Evidence-Based Mental Health, 19, 35-38. PMID: 27053196

Admon, R, Nickerson, LD, Dillon, DG, Holmes, AJ, Bogdan, R, Kumar, P, Dougherty, DD, Iosifescu, DV, Mischoulon, D, Fava, M, Pizzagalli, DA. (2015). Dissociable cortico-striatal connectivity abnormalities in major depression in response to monetary gains and penalties. Psychological Medicine, 45, 121-131. PMID: 25055809

DeWilde, KE, Levitch, CF, Murrough, JW, Mathew, SJ, Iosifescu, DV. (2015). The promise of ketamine for treatment-resistant depression: Current evidence and future directions. Annals of the New York Academy of Sciences, 1345, 47-58. PMID: 25649308

Feder, A, Murrough, JW. (2015). Ketamine for posttraumatic stress disorder – Reply. JAMA Psychiatry, 72, 95-96. PMID: 25564791

Fletcher, K, Parker, G, Paterson, A, Fava, M, Iosifescu, D, Pizzagalli, DA. (2015). Anhedonia in melancholic and non-melancholic depressive disorders. Journal of Affective Disorders, 184, 81-88. PMID: 26074016

Gonzalez Arnold, J, Salcedo, S, Ketter, TA, Calabrese, JR, Rabideau, DJ, Nierenberg, AA, Bazan, M, Leon, AC, Friedman, ES, Iosifescu, D, Sylvia, LG, Ostacher, M, Thase, M, Reilly-Harrington, NA, Bowden, CL. (2015). An exploratory study of responses to low-dose lithium in African Americans and Hispanics. Journal of Affective Disorders, 178, 224-228. PMID: 25827507

Guajardo, VD, Terroni, L, Sobreiro, MDFM, Zerbini, MIDS, Tinone, G, Scaff, M, Iosifescu, DV, De Lucia, MCS, Fráguas, R. (2015). The influence of depressive symptoms on quality of life after stroke: A prospective study. Journal of Stroke and Cerebrovascular Diseases, 24, 201-209. PMID: 25440338

Lener, MS, Iosifescu, DV. (2015). In pursuit of neuroimaging biomarkers to guide treatment selection in major depressive disorder: A review of the literature. Annals of the New York Academy of Sciences, 1344, 50-65. PMID: 25854817

Leuchter, AF, Cook, IA, Feifel, D, Goethe, JW, Husain, M, Carpenter, LL, Thase, ME, Krystal, AD, Philip, NS, Bhati, MT, Burke, WJ, Howland, RH, Sheline, YI, Aaronson, ST, Iosifescu, DV, O'Reardon, JP, Gilmer, WS, Jain, R, Burgoyne, KS, Phillips, B, Manberg, PJ, Massaro, J, Hunter, AM, Lisanby, SH, George, MS. (2015). Efficacy and safety of low-field synchronized transcranial magnetic stimulation (sTMS) for treatment of major depression. Brain Stimulation, 8, 787-794. PMID: 26143022

Iacoviello, BM, Charney, DS. (2015). Developing cognitive-emotional training exercises as interventions for mood and anxiety disorders. European Psychiatry, 30, 75-81. PMID: 25451246

Iacoviello, BM, Shenoy, A, Braoude, J, Jennings, T, Vaidya, S, Brouwer, J, Haydel, B, Arroyo, H, Thakur, D., Leinwand, J, Rudow, DL. (2015). The live donor assessment tool: a psychosocial assessment tool for live organ donors. Psychosomatics, 56, 254-261. PMID: 25975858

Iosifescu, DV. (2015). Maintaining the initial clinical response after ketamine in bipolar and unipolar depression: An important next-step challenge. Journal of Clinical Psychiatry, 76, 738-740. PMID: 26132676

Kotov, R, Bromet, EJ, Schechter, C, Broihier, J, Feder, A, Friedman-Jimenez, G, Gonzalez, A, Guerrera, K, Kaplan, J, Moline, J, Pietrzak, RH, Reissman, D, Ruggero, C, Southwick, SM, Udasin, I, Von Korff, M, Luft, BJ. (2015). Posttraumatic stress disorder and the risk of respiratory problems in world trade center responders: Longitudinal test of a pathway. Psychosomatic Medicine, 77, 438-448. PMID: 25919367

Murrough, JW. (2015). Glutamate NMDA receptor modulators for the treatment of depression: Trials and tribulations. Psychopharmacology, 232, 1497-1499. PMID: 25752888.

Murrough, JW, Burdick, KE, Levitch, CF, Perez, AM, Brallier, JW, Chang, LC, Foulkes, A, Charney, DS, Mathew, SJ, Iosifescu, DV. (2015). Neurocognitive Effects of Ketamine and Association with Antidepressant Response in Individuals with Treatment-Resistant Depression: A Randomized Controlled Trial. Neuropsychopharmacology, 40, 1084-1090. PMID: 25374095

Murrough, JW, Collins, KA, Fields, J, DeWilde, KE, Phillips, ML, Mathew, SJ, Wong, E, Tang, CY, Charney, DS, Iosifescu, DV. (2015). Regulation of neural responses to emotion perception by ketamine in individuals with treatment-resistant major depressive disorder. Translational Psychiatry, 5, e509. PMID: 25689570

Murrough, JW, Soleimani, L, Dewilde, KE, Collins, KA, Lapidus, KA, Iacoviello, BM, Lener, M, Kautz, M, Kim, J, Stern, JB, Price, RB, Perez, AM, Brallier, JW, Rodriguez, GJ, Goodman, WK, Iosifescu, DV, Charney, DS. (2015). Ketamine for rapid reduction of suicidal ideation: A randomized controlled trial. Psychological Medicine, 45, 3571-3580. PMID: 26266877

Murrough, JW, Yaqubi, S, Sayed, S, Charney, DS. (2015). Emerging drugs for the treatment of anxiety. Expert Opinion on Emerging Drugs, 20, 393-406. PMID: 26012843

Ostacher, MJ, Nierenberg, AA, Rabideau, D, Reilly-Harrington, NA, Sylvia, L.G., Gold, A.K., Shesler, L.W., Ketter, TA, Bowden, CL, Calabrese, JR, Friedman, ES, Iosifescu, DV, Thase, ME, Leon, AC, Trivedi, MH. (2015). A clinical measure of suicidal ideation, suicidal behavior, and associated symptoms in bipolar disorder: Psychometric properties of the Concise Health Risk Tracking Self-Report (CHRT-SR). Journal of Psychiatric Research, 71, 126-133. PMID: 26476489

Peyrot, WJ, Lee, SH, Milaneschi, Y, Abdellaoui, A, Byrne, EM, Esko, T, Zhao, W. (2015). The association between lower educational attainment and depression owing to shared genetic effects? Results in ~25 000 subjects. Molecular Psychiatry, 20, 735-743. PMID: 25917368

Sayed, S, Iacoviello, BM, Charney, DS. (2015). Risk factors for the development of psychopathology following trauma. Current Psychiatry Reports, 17, 612. PMID: 26206108

Terroni, L, Amaro, E, Iosifescu, DV, Mattos, P, Yamamoto, FI, Tinone, G, Conforto, AB, Sobreiro, MFM, Guajardo, VD, De Lucia, MCS, Moreira, AC, Scaff, M, C Leite, C, Fraguas, R. (2015). The association of post-stroke anhedonia with salivary cortisol levels and stroke lesion in hippocampal/parahippocampal region. Neuropsychiatric Disease and Treatment, 11, 233-242. PMID: 25678790

Treadway, MT, Waskom, ML, Dillon, DG, Holmes, AJ, Park, MTM, Chakravarty, MM, Dutra, SJ, Polli, FE, Iosifescu, DV, Fava, M, Gabrieli, JDE, Pizzagalli, DA. (2015). Illness progression, recent stress, and morphometry of hippocampal subfields and medial prefrontal cortex in major depression. Biological Psychiatry, 77, 285-294. PMID: 25109665

Wan, L-, Levitch, CF, Perez, AM, Brallier, JW, Iosifescu, DV, Chang, LC, Foulkes, A, Mathew, SJ, Charney, DS, Murrough, JW. (2015). Ketamine safety and tolerability in clinical trials for treatment-resistant depression. Journal of Clinical Psychiatry, 76, 247-252. PMID: 25271445

Zvolensky, MJ, Farris, SG, Kotov, R, Schechter, CB, Bromet, E, Gonzalez, A., Vujanovic, A, Pietrzak, R.H., Crane, M, Kaplan, J, Moline, J, Southwick, SM, Feder, A, Udasin, I, Reissman, DB, Luft, BJ. (2015). World Trade Center disaster and sensitization to subsequent life stress: A longitudinal study of disaster responders. Preventive Medicine, 75, 70-74. PMID: 25840022

Zvolensky, MJ, Farris, SG, Kotov, R, Schechter, CB, Bromet, E, Gonzalez, A, Vujanovic, A, Pietrzak, RH, Crane, M, Kaplan, J, Moline, J, Southwick, SM, Feder, A, Udasin, I, Reissman, DB, Luft, BJ. (2015). Posttraumatic stress symptoms and smoking among World Trade Center disaster responders: A longitudinal investigation. Comprehensive Psychiatry, 63, 46-54. PMID: 26555491

Zvolensky, MJ, Kotov, R, Schechter, CB, Gonzalez, A, Vujanovic, A, Pietrzak, RH, Crane, M, Kaplan, J, Moline, J, Southwick, SM, Feder, A, Udasin, I, Reissman, DB, Luft, BJ. (2015). Post-disaster stressful life events and WTC-related posttraumatic stress, depressive symptoms, and overall functioning among responders to the World Trade Center disaster. Journal of Psychiatric Research, 61, 97-105. PMID: 25499737

Beech, RD, Leffert, JJ, Lin, A, Sylvia, LG, Umlauf, S, Mane, S, Zhao, H, Bowden, C, Calabrese, JR, Friedman, ES, Ketter, TA, Iosifescu, DV, Reilly-Harrington, NA, Ostacher, M, Thase, ME, Nierenberg, A. (2014). Gene-expression differences in peripheral blood between lithium responders and non-responders in the Lithium Treatment-Moderate dose Use Study (LiTMUS)Pharmacogenomics Journal, 14, 182-191.

Dunlop, BW, Rothbaum, BO, Binder, EB, Duncan, E, Harvey, PD, Jovanovic, T, Kelley, ME, Kinkead, B, Kutner, M, Iosifescu, DV, Mathew, SJ, Neylan, TC, Kilts, CD, Nemeroff, CB, Mayberg, HS. (2014). Evaluation of a corticotropin releasing hormone type 1 receptor antagonist in women with posttraumatic stress disorder: Study protocol for a randomized controlled trialTrials, 15, 240.

Feder, A, Parides, MK, Murrough, JW, Perez, AM, Morgan, JE, Saxena, S, Kirkwood, K, Aan Het Rot, M, Lapidus, KAB, Wan, L-B, Iosifescu, D, Charney, DS. (2014). Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: A randomized clinical trialJAMA Psychiatry, 71, 681-688.

Friedman, ES, Calabrese, JR, Ketter, TA, Leon, AC, Thase, ME, Bowden, CL, Sylvia, LG, Ostracher, MJ, Severe, J, Iosifescu, DV, Nierenberg, AA, Reilly-Harrington, NA. (2014). Using comparative effectiveness design to improve the generalizability of bipolar treatment trials data: Contrasting LiTMUS baseline data with pre-existing placebo controlled trialsJournal of Affective Disorders152, 97-104.

Haile, CN, Murrough, JW, Iosifescu, DV, Chang, LC, Al Jurdi, RK, Foulkes, A, Iqbal, S, Mahoney, JJ, De La Garza, R, Charney, DS, Newton, TF, Mathew, SJ. (2014). Plasma brain derived neurotrophic factor (BDNF) and response to ketamine in treatment-resistant depressionInternational Journal of Neuropsychopharmacology, 17, 331-336.

Harper, DG, Jensen, JE, Ravichandran, C, Sivrioglu, Y, Silveri, M, Iosifescu, DV, Renshaw, PF, Forester, BP. (2014). Tissue-specific differences in brain phosphodiesters in late-life major depressionAmerican Journal of Geriatric Psychiatry, 22, 499-509.

Hodes, GE, Pfau, ML, Leboeuf, M, Golden, SA, Christoffel, DJ, Bregman, D, Rebusi, N, Heshmati, M, Aleyasin, H, Warren, BL, Lebonté, B, Horn, S., Lapidus, KA, Stelzhammer, V., Wong, EHF, Bahn, S, Krishnan, V, Bolaños-Guzman, CA, Murrough, JW, Merad, M, Russo, S.J. (2014). Individual differences in the peripheral immune system promote resilience versus susceptibility to social stressProceedings of the National Academy of Sciences of the United States of America, 111, 16136-16141.

Hoogenboom, WS, Perlis, RH, Smoller, JW, Zeng-Treitler, Q, Gainer, VS, Murphy, SN, Churchill, SE, Kohane, IS, Shenton, ME, Iosifescu, DV. (2014). Limbic system white matter microstructure and long-term treatment outcome in ajor depressive disorder: A diffusion tensor imaging study using legacy dataWorld Journal of Biological Psychiatry, 15, 122-134.

Iacoviello, BM, Wu, G, Abend, R, Murrough, JW, Feder, A, Fruchter, E, Levinstein, Y, Wald, I, Bailey, CR, Pine, DS, Neumeister, A, Bar-Haim, Y, Charney, DS. (2014). Attention Bias Variability and Symptoms of Posttraumatic Stress DisorderJournal of Traumatic Stress, 27, 232-239.

Iacoviello, BM, Wu, G, Alvarez, E, Huryk, K, Collins, KA, Murrough, JW, Iosifescu, DV, Charney, DS. (2014). Cognitive-emotional training as an intervention for major depressive disorderDepression and Anxiety, 31, 699-706.

Ivanov, I, Murrough, JW, Bansal, R, Hao, X, Peterson, BS. (2014). Cerebellar morphology and the effects of stimulant medications in youths with attention deficit-hyperactivity disorderNeuropsychopharmacology, 39, 718-726.

Kaye, JL, Dunlop, BW, Iosifescu, DV, Mathew, SJ, Kelley, ME, Harvey, PD. (2014). Cognition, functional capacity, and self-reported disability in women with posttraumatic stress disorder: Examining the convergence of performance-based measures and self-reportsJournal of Psychiatric Research, 57, 51-57.

Kemp, DE, Sylvia, LG, Calabrese, JR, Nierenberg, AA, Thase, ME, Reilly-Harrington, NA, Ostacher, MJ, Leon, AC, Ketter, TA, Friedman, ES, Bowden, CL, Rabideau, DJ, Pencina, M, Iosifescu, DV. (2014). General medical burden in bipolar disorder: Findings from the LiTMUS comparative effectiveness trialActa Psychiatrica Scandinavica, 129, 24-34.

Lapidus, KAB, Gabbay, V, Mao, X, Johnson, A, Murrough, JW, Mathew, SJ, Shungu, DC. (2014). In vivo 1H MRS study of potential associations between glutathione, oxidative stress and anhedonia in major depressive disorderNeuroscience Letters, 569, 74-79.

Lapidus, KAB, Levitch, CF, Perez, AM, Brallier, JW, Parides, MK, Soleimani, L, Feder, A, Iosifescu, DV, Charney, DS, Murrough, J.W. (2014). A randomized controlled trial of intranasal ketamine in major depressive disorderBiological Psychiatry, 76, 970-976.

Murrough, JW, Wan, L-B, Iacoviello, B, Collins, KA, Solon, C, Glicksberg, B, Perez, AM, Mathew, SJ, Charney, DS, Iosifescu, DV, Burdick, KE. (2014). Neurocognitive effects of ketamine in treatment-resistant major depression: Association with antidepressant responsePsychopharmacology, 231, 481-488.

O'Dushlaine, C, Ripke, S, Ruderfer, DM, Hamilton, SP, Fava, M, Iosifescu, DV, Kohane, IS, Churchill, SE, Castro, VM, Clements, CC, Blumenthal, SR, Murphy, SN, Smoller, JW, Perlis, RH. (2014). Rare copy number variation in treatment-resistant major depressive disorderBiological Psychiatry, 76, 536-541.

Ostacher, MJ, Iosifescu, DV, Hay, A, Blumenthal, SR, Sklar, P, Perlis, RH. (2014). Pilot investigation of isradipine in the treatment of bipolar depression motivated by genome-wide associationBipolar Disorders, 16, 199-203.

Pietrzak, RH, Feder, A, Schechter, CB, Singh, R, Cancelmo, L, Bromet, EJ, Katz, CL, Reissman, DB, Ozbay, F, Sharma, V, Crane, M, Harrison, D, Herbert, R, Levin, SM, Luft, BJ, Moline, JM, Stellman, JM, Udasin, IG, El-Gabalawy, R, Landrigan, PJ, Southwick, SM. (2014). Dimensional structure and course of post-traumatic stress symptomatology in World Trade Center respondersPsychological Medicine, 44, 2085-2098.

Pietrzak, RH, Feder, A, Singh, R, Schechter, CB, Bromet, EJ, Katz, CL, Reissman, DB, Ozbay, F, Sharma, V, Crane, M, Harrison, D, Herbert, R, Levin, SM, Luft, BJ, Moline, JM, Stellman, JM, Udasin, IG., Landrigan, PJ, Southwick, SM. (2014). Trajectories of PTSD risk and resilience in World Trade Center responders: An 8-year prospective cohort studyPsychological Medicine, 44, 205-219.

Price, RB, Iosifescu, DV, Murrough, JW, Chang, LC, Al Jurdi, RK, Iqbal, SZ, Soleimani, L, Charney, DS, Foulkes, AL, Mathew, SJ. (2014). Effects of ketamine on explicit and implicit suicidal cognition: A randomized controlled trial in treatment-resistant depressionDepression and Anxiety, 31, 335-343.

Rabideau, DJ, Nierenberg, AA, Sylvia, LG, Friedman, ES, Bowden, CL, Thase, ME, Ketter, TA, Ostacher, MJ, Reilly-Harrington, N, Iosifescu, DV, Calabrese, JR, Leon, AC, Schoenfeld, DA. (2014). A novel application of the Intent to Attend assessment to reduce bias due to missing data in a randomized controlled clinical trialClinical Trials, 11, 494-502.

Rudow, DL, Iacoviello, BM, Charney, D. (2014). Resilience and personality traits among living liver and kidney donorsProgress in Transplantation, 24, 82-90.

Sobreiro, MFM, Miotto, EC, Terroni, L, Tinone, G, Iosifescu, DV, De Lucia, MCS, Scaff, M, Leite, CDC, Amaro Jr, E, Fraguas, R. (2014). Executive function and depressive symptoms of retardation in nonelderly stroke patientsJournal of Clinical and Experimental Neuropsychology, 36, 636-647.

Sylvia, LG, Rabideau, DJ, Nierenberg, AA, Bowden, CL, Friedman, ES, Iosifescu, DV, Thase, ME, Ketter, T, Greiter, EA, Calabrese, JR, Leon, AC, Ostacher, MJ, Reilly-Harrington, N. (2014). The effect of personalized guideline-concordant treatment on quality of life and functional impairment in bipolar disorderJournal of Affective Disorders, 169, 144-148.

Sylvia, LG, Reilly-Harrington, NA, Leon, AC, Kansky, CI, Calabrese, JR, Bowden, CL, Ketter, TA, Friedman, ES, Iosifescu, DV, Thase, ME, Ostacher, MJ, Keyes, M, Rabideau, D, Nierenberg, AA (2014). Medication adherence in a comparative effectiveness trial for bipolar disorderActa Psychiatrica Scandinavica, 129, 359-365.

Castro, VM, Clements, CC, Murphy, SN, Gainer, VS, Fava, M, Weilburg, JB, Erb, JL, Churchill, SE, Kohane, IS., Iosifescu, DV, Smoller, JW, Perlis, RH. (2013). QT interval and antidepressant use: A cross sectional study of electronic health records. BMJ, 346(7894),f288.

Cook, IA, Hunter, AM, Gilmer, WS, Iosifescu, DV, Zisook, S, Burgoyne, KS, Howland, RH, Trivedi, MH, Jain, R, Greenwald, S, Leuchter, AF. (2013). Quantitative electroencephalogram Biomarkers for predicting likelihood and speed of achieving sustained remission in Major Depression: A report from the Biomarkers for Rapid Identification of Treatment Effectiveness in Major Depression (BRITE-MD) trial. Journal of Clinical Psychiatry, 74, 51-56.

Cusin, C, Iovieno, N, Iosifescu, DV, Nierenberg, AA, Fava, M, Rush, AJ, Perlis, RH. (2013). A randomized, double-blind, placebo-controlled trial of pramipexole augmentation in treatment-resistant major depressive disorder. Journal of Clinical Psychiatry, 74, e636-e641.

Feder, A, Ahmad, S, Lee, EJ, Morgan, JE, Singh, R, Smith, BW, Southwick, SM, Charney, DS. (2013). Coping and PTSD symptoms in Pakistani earthquake survivors: Purpose in life, religious coping and social support. Journal of Affective Disorders, 147, 156-163.

Hoogenboom, WS, Perlis, RH, Smoller, JW, Zeng-Treitler, Q, Gainer, VS, Murphy, SN, Churchill, SE, Kohane, IS, Shenton, ME, Iosifescu, DV. (2013). Feasibility of studying brain morphology in major depressive disorder with structural magnetic resonance imaging and clinical data from the electronic medical record: A pilot study. Psychiatry Research - Neuroimaging, 211, 202-213.

Iacoviello, BM, Alloy, LB, Abramson, LY, Choi, JY, Morgan, JE. (2013). Patterns of symptom onset and remission in episodes of hopelessness depression. Depression and Anxiety, 30, 564-573.

Lapidus, KAB, Soleimani, L, Murrough, JW. (2013). Novel glutamatergic drugs for the treatment of mood disorders. Neuropsychiatric Disease and Treatment, 9, 1101-1112.

McClure, MM, Harvey, PD, Bowie, CR, Iacoviello, B, Siever, LJ. (2013). Functional outcomes, functional capacity, and cognitive impairment in schizotypal personality disorder. Schizophrenia Research, 144, 146-150.

Murrough, JW, Iosifescu, DV, Chang, LC, Al Jurdi, RK, Green, CE, Perez, AM, Iqbal, S, Pillemer, S, Foulkes, A, Shah, A, Charney, DS, Mathew, SJ. (2013). Antidepressant efficacy of ketamine in treatment-resistant major depression: A two-site randomized controlled trial. American Journal of Psychiatry, 170, 1134-1142.

Murrough, JW, Perez, AM, Pillemer, S, Stern, J, Parides, MK, Aan Het Rot, M, Collins, KA, Mathew, SJ, Charney, DS, Iosifescu, DV. (2013). Rapid and longer-term antidepressant effects of repeated ketamine infusions in treatment-resistant major depression. Biological Psychiatry, 74, 250-256.

Nierenberg, AA, Friedman, ES, Bowden, CL, Sylvia, LG, Thase, ME, Ketter, T, Ostacher, MJ, Leon, AC, Reilly-Harrington, N, Iosifescu, DV, Pencina, M, Severe, JB, Calabrese, JR. (2013). Lithium treatment moderate-dose use study (LiTMUS) for bipolar disorder: A randomized comparative effectiveness trial of optimized personalized treatment with and without lithium. American Journal of Psychiatry, 170, 102-110.

Nierenberg, AA, Kansky, C, Brennan, BP, Shelton, RC, Perlis, R, Iosifescu, DV. (2013). Mitochondrial modulators for bipolar disorder: A pathophysiologically informed paradigm for new drug development. Australian and New Zealand Journal of Psychiatry, 47, 26-42.

Reilly-Harrington, NA, Sylvia, LG, Leon, AC, Shesler, LW, Ketter, TA, Bowden, CL, Calabrese, JR, Friedman, ES, Ostacher, MJ, Iosifescu, DV, Rabideau, DJ, Thase, ME, Nierenberg, AA. (2013). The Medication Recommendation Tracking Form: A novel tool for tracking changes in prescribed medication, clinical decision making, and use in comparative effectiveness research. Journal of Psychiatric Research, 47, 1686-1693.

Soleimani L, Welch A, Murrough JW. (2015). Does Keamine Have Rapid Anti-Suicidal Ideation Effects? Curr Treat Options Psychiatry. 2(4): 383-393.

Sylvia, LG, Iosifescu, D, Friedman, ES, Bernstein, EE, Bowden, CL, Ketter, TA, Reilly-Harrington, NA, Leon, AC, Calabrese, JR, Ostacher, MJ, Rabideau, DJ, Thase, ME, Nierenberg, AA. (2013). Use of treatment services in a comparative effectiveness study of bipolar disorder. Psychiatric Services, 64, 1119-1126.

Wu, G, Feder, A, Cohen, H, Kim, JJ, Calderon, S, Charney, DS, Mathé, AA. (2013). Understanding resilience. Frontiers in Behavioral Neuroscience.

Alim, TN, Lawson, WB, Feder, A, Iacoviello, BM, Saxena, S, Bailey, CR, Greene, AM, Neumeister, A. (2012). Resilience to meet the challenge of addiction: Psychobiology and clinical considerations. Alcohol Research: Current Reviews, 34, 506-515.

Castro, VM, Gallagher, PJ, Clements, CC, Murphy, SN, Gainer, VS, Fava, M, Weilburg, JB, Churchill, SE, Kohane, IS, Iosifescu, DV, Smoller, JW, Perlis, RH. (2012). Incident user cohort study of risk for gastrointestinal bleed and stroke in individuals with major depressive disorder treated with antidepressants. BMJ Open, 2, -.

Fava, M, Mischoulon, D, Iosifescu, D, Witte, J, Pencina, M, Flynn, M, Harper, L, Levy, M, Rickels, K, Pollack, M. (2012). A double-blind, placebo-controlled study of aripiprazole adjunctive to antidepressant therapy among depressed outpatients with inadequate response to prior antidepressant therapy (ADAPT-A study):(Psychotherapy and Psychosomatics (2012) 81, (87-97)). Psychotherapy and Psychosomatics, 81, 261-.

Gallagher, PJ, Castro, V, Fava, M, Weilburg, JB, Murphy, SN, Gainer, V.S., Churchill, SE, Kohane, IS, Iosifescu, DV, Smoller, JW, Perlis, RH. (2012). Antidepressant response in patients with major depression exposed to NSAIDs: A pharmacovigilance study. American Journal of Psychiatry, 169, 1065-1072.

Hoffman, DA, Debattista, C, Valuck, RJ, Iosifescu, DV. (2012). Measuring Severe Adverse Events and Medication Selection Using a "PEER Report" for Nonpsychotic Patients: A Retrospective Chart Review. Neuropsychiatric Disease and Treatment, 8, 277-284.

Iosifescu, DV. (2012). The relation between mood, cognition and psychosocial functioning in psychiatric disorders. European Neuropsychopharmacology, 22, S499-S504.

Kellner, CH, Greenberg, RM, Murrough, JW, Bryson, EO, Briggs, MC, Pasculli, RM. (2012). ECT in treatment-resistant depression. American Journal of Psychiatry, 169, 1238-1244.

Mathew, SJ, Shah, A, Lapidus, K, Clark, C, Jarun, N, Ostermeyer, B, Murrough, JW. (2012). Ketamine for treatment-resistant unipolar depression: Current evidence. CNS Drugs, 26, 189-204.

Mischoulon, D, Lamon-Fava, S, Selhub, J, Katz, J, Papakostas, GI, Iosifescu, DV, Yeung, AS, Dording, CM, Farabaugh, AH, Clain, AJ, Baer, L, Alpert, JE, Nierenberg, AA, Fava, M. (2012). Prevalence of MTHFR C677T and MS A2756G polymorphisms in major depressive disorder, and their impact on response to fluoxetine treatment. CNS Spectrums, 17, 76-86.

Murrough, JW. (2012). Ketamine as a novel antidepressant: From synapse to behavior. Clinical Pharmacology and Therapeutics, 91, 303-309.

Murrough, JW, Charney, DS. (2012). Is there anything really novel on the antidepressant horizon?. Current Psychiatry Reports, 14, 643-649.

Neumeister, A, Normandin, MD, Murrough, JW, Henry, S, Bailey, CR, Luckenbaugh, DA, Tuit, K, Zheng, M-Q, Galatzer-Levy, IR, Sinha, R., Carson, RE, Potenza, MN, Huang, Y. (2012). Positron Emission Tomography Shows Elevated Cannabinoid CB 1 Receptor Binding in Men with Alcohol Dependence. Alcoholism: Clinical and Experimental Research, 36, 2104-2109.

Perlis, RH, Iosifescu, DV, Castro, V.M., Murphy, SN, Gainer, VS, Minnier, J, Cai, T, Goryachev, S, Zeng, Q, Gallagher, PJ, Fava, M, Weilburg, JB, Churchill, SE, Kohane, IS, Smoller, JW. (2012). Using electronic medical records to enable large-scale studies in psychiatry: Treatment resistant depression as a model. Psychological Medicine, 42, 41-50.

Russo, SJ, Murrough, JW, Han, M-H, Charney, DS, Nestler, EJ. (2012). Neurobiology of resilience. Nature Neuroscience, 15, 1475-1484.

Shungu, DC, Weiduschat, N, Murrough, JW, Mao, X, Pillemer, S, Dyke, JP, Medow, MS, Natelson, BH, Stewart, JM, Mathew, SJ. (2012). Increased ventricular lactate in chronic fatigue syndrome. III. Relationships to cortical glutathione and clinical symptoms implicate oxidative stress in disorder pathophysiology. NMR in Biomedicine, 25, 1073-1087.

Sylvia, LG, Reilly-Harrington, NA, Leon, AC, Kansky, CI, Ketter, TA, Calabrese, JR, Thase, ME, Bowden, CL, Friedman, ES, Ostacher, MJ, Iosifescu, DV, Severe, J, Keyes, M, Nierenberg, AA. (2012). Methods to limit attrition in longitudinal comparative effectiveness trials: Lessons from the Lithium treatment-moderate dose use study (LiTMUS) for bipolar disorder. Clinical Trials, 9, 94-101.

Brodman, DM, Clark, CT, Murrough, JW, Mathew, SJ, Harvey, PD. (2011). The implications of neurocognitive deficits in posttraumatic stress disorderPsychiatric Annals, 41, 408-412.

DeBattista, C, Kinrys, G, Hoffman, D, Goldstein, C, Zajecka,  Kocsis, Teicher, M, Potkin, S, Preda, A, Multani, G, Brandt, L, Schiller, M, Iosifescu, D, Fava, M. (2011). The use of referenced-EEG (rEEG) in assisting medication selection for the treatment of depressionJournal of Psychiatric Research, 45, 64-75.

Fava, M, Schaefer, K, Huang, H, Wilson, A, Iosifescu, DV, Mischoulon, D, Wessel, TC. (2011). A post hoc analysis of the effect of nightly administration of eszopiclone and a selective serotonin reuptake inhibitor in patients with insomnia and anxious depressionJournal of Clinical Psychiatry, 72, 473-479.

Feder, A, Charney, D, Collins, K. (2011). Neurobiology of resilienceResilience and Mental Health: Challenges Across the Lifespan, 1-29.

Feder, A, Skipper, J, Blair, JR, Buchholz, K, Mathew, SJ, Schwarz, M, Doucette, JT, Alonso, A, Collins, KA, Neumeister, A, Charney, DS. (2011). Tryptophan depletion and emotional processing in healthy volunteers at high risk for depressionBiological Psychiatry, 69, 804-807.

Greenblatt, JM, Sussman, C, Jameson, M, Yuan, L, Hoffman, DA, Iosifescu, DV. (2011). Retrospective chart review of a referenced EEG database in assisting medication selection for treatment of depression in patients with eating disordersNeuropsychiatric Disease and Treatment, 7, 529-541.

Hoffman, DA, Schiller, M, Greenblatt, JM, Iosifescu, DV. (2011). Polypharmacy or medication washout: An old tool revisitedNeuropsychiatric Disease and Treatment, 7, 639-648.

Iosifescu, DV. (2011). Electroencephalography-derived biomarkers of antidepressant responseHarvard Review of Psychiatry, 19, 144-154.

Iosifescu, DV, Lapidus, K. (2011). The role of neuroimaging and electrophysiology (EEG) as predictors of treatment response in major depressive disorderClinical Neuropsychiatry, 8, 47-60.

Mathew, SJ, Vythilingam, M, Murrough, JW, Zarate, CA, Feder, A, Luckenbaugh, DA, Kinkead, B, Parides, MK, Trist, DG, Bani, MS, Bettica, PU, Ratti, EM, Charney, DS. (2011). A selective neurokinin-1 receptor antagonist in chronic PTSD: A randomized, double-blind, placebo-controlled, proof-of-concept trialEuropean Neuropsychopharmacology, 21, 221-229.

Murrough, JW, Charney, DS. (2011). The serotonin transporter and emotionality: Risk, resilience, and new therapeutic opportunitiesBiological Psychiatry, 69, 510-512.

Murrough, JW, Czermak, C, Henry, S, Nabulsi, N, Gallezot, J-D, Gueorguieva, R, Planeta-Wilson, B, Krystal, J.H., Neumaier,CF, Huang, Y, Ding, Y-S, Carson, RE, Neumeister, A. (2011). The effect of early trauma exposure on serotonin type 1B receptor expression revealed by reduced selective radioligand bindingArchives of General Psychiatry, 68, 892-900.

Murrough, JW, Gallo, JM, Collins, KA, Aan Het Rot, M., Charney, DS. (2011). Reply to: Dose- and exposure-response to ketamine in depressionBiological Psychiatry, 70, e11-e12.

Murrough, JW, Henry, S, Hu, J, Gallezot, J-D, Planeta-Wilson, B, Neumaier, JF, Neumeister, A. (2011). Reduced ventral striatal/ventral pallidal serotonin1B receptor binding potential in major depressive disorderPsychopharmacology, 213, 547-553.

Murrough, JW, Huang, Y, Hu, J, Henry, S, Williams, W, Gallezot, J-D, Bailey, CR, Krystal, JH, Carson, RE, Neumeister, A. (2011). Reduced amygdala serotonin transporter binding in posttraumatic stress disorderBiological Psychiatry, 70, 1033-1038.

Murrough, JW, Iacoviello, B, Neumeister, A, Charney, DS, Iosifescu, DV. (2011). Cognitive dysfunction in depression: Neurocircuitry and new therapeutic strategiesNeurobiology of Learning and Memory, 96, 553-563.

Murrough, JW, Neumeister, A. (2011). The serotonin 1B receptor: A new target for depression therapeutics?Biological Psychiatry, 69, 714-715.

Murrough, JW, Perez, AM, Mathew, SJ, Charney, DS. (2011). A case of sustained remission following an acute course of ketamine in treatment-resistant depressionJournal of Clinical Psychiatry, 72, 414-415.

Santos, DM, Lage, LV, Jabur, EK, Kaziyama, HHS, Iosifescu, DV, de Lucia, MCS., FrÌÁguas, R. (2011). The association of major depressive episode and personality traits in patients with fibromyalgiaClinics, 66, 973-978.

Soleimani, L, Lapidus, KAB, Iosifescu, DV. (2011). Diagnosis and Treatment of Major Depressive DisorderNeurologic Clinics, 29, 177-193.

Terroni, L, Amaro Jr., E, Iosifescu, DV, Tinone, G, Sato, JR, Leite, CC, Sobreiro, MFM, Lucia, MCS, Scaff, M, FrÌÁguas, R. (2011). Stroke lesion in cortical neural circuits and post-stroke incidence of major depressive episode: A 4-month prospective studyWorld Journal of Biological Psychiatry, 12, 539-548.

Wu, G, Feder, A, Wegener, G, Bailey, C, Saxena, S, Charney, D, Mathe, AA. (2011). Central functions of neuropeptide y in mood and anxiety disordersExpert Opinion on Therapeutic Targets, 15, 1317-1331.