About the Program

Dr. Julio Aguirre-Ghiso and Dr. Brett Miles explain how the research at the Program is bringing patients more treatment options, including innovative clinical trials, as well as surgical and technological improvements. 

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Head and Neck Cancer Research Program

Mount Sinai‚Äôs Department of Otolaryngology/Head and Neck Surgery was established as one of the first of its kind in the United States. At the Head and Neck Cancer Research Program, our dynamic team of physician-scientists, biologists, and researchers utilizes a multidisciplinary approach to translational and clinical research. Our goal is to discover new insights into head and neck cancer biology and forge new treatment options, while providing a platform for rapid translation from bench to bedside.  Read more

Oral Cancer Patient Story

Maxine Prescott opted to participate in the Advaxis oral cancer vaccine clinical trial and transoral robotic surgery (TORS). Now she's clear of cancer, has lots of energy, and feels better than ever.

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HPV-related Cancer Vaccine Trial

A clinical trial testing the ADXS 11-001 vaccine for patients who have an HPV-related oral cancer is available at Mount Sinai.

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Contact Us

Julio Aguirre-Ghiso, PhD
Director, Head and Neck Cancer Basic Research
Tel: 212-241-9582
Send e-mail

Brett A. Miles, DDS MD FACS
Assistant Professor
Head and Neck Oral and Maxillofacial Surgery
Oncology Microvascular Reconstructive Surgery
Tel: 212-241-2253

Leslie Waters-Martin
Research Program Coordinator
Tel: 212-241-7107

Advaxis Clinical Trial

Researchers at Mount Sinai are conducting a clinical trial testing a novel vaccine for patients with HPV-related oropharyngeal (tonsil and tongue base) cancer who are eligible to undergo robot-assisted surgery. Watch video