Laboratory Services

Comparative Pathology Laboratory (CPL)

The CPL provides in-house gross anatomic pathology and clinical pathology services in support of the research programs at the Mount Sinai Health System and the clinical programs of the Center for Comparative Medicine and Surgery (CCMS).

The lab is under the direction of a full-time veterinary pathologist. Staff includes a laboratory manager and two full-time laboratory technicians. The primary laboratory is located on the 26th floor of Annenberg, Room 26-92. Laboratory support areas are two necropsy suites, Room 26-93 and Icahn Medical Institute S1-27H. Both necropsy rooms are equipped with down draft tables, surgical lights, and dissecting tools. Both necropsy rooms are available for use by the research community by signing up online.

The CPL has full histology capabilities with a Sakura Tissue-Tek VIP tissue Processor, Leica EG1150 embedding station, Microm microtome and TBS floatation workstation. The CPL also has multiple single-headed microscopes (light, phase contrast, fluorescent, dissecting) and a doubled-headed teaching microscope with video color camera and monitor. Other laboratory equipment includes: Bio-Plex 200 System from Bio-Rad for performing rodent serology assays and GeneAMP (Perkin Elmer) PCR equipment.

Although the majority of diagnostics are performed in-house, commercial and academic labs are used for confirmation of positive serology results. Nonhuman primate virology is also performed by commercial labs. The following materials are sent to reference laboratories: simian serology panel, rodent pathogen IMPACT for cell lines or tumors, endocrinology tests, and other special assays. Those commercial and academic labs include: Charles River Lab, BioReliance Lab, ALX IDEXX and RADIL IDEXX.

The CPL works closely with several existing SRF facilities on campus (Biorepository/Histology SRF, qPCR SRF, and Microscopy SRF) to increase the support available to the research community.