Developmental & Regenerative Biology | Icahn School of Medicine

Regenerative medicine holds incredible potential for improving the lives of countless individuals. The Department of Stem Cell Biology and Regenerative Medicine is at the forefront of this field, working to turn our scientific discoveries into better care for patients both within and beyond New York City.

Situated within the Icahn School of Medicine, our interdisciplinary research teams study a wide range of conditions and diseases, from wound repair and hair loss to Alzheimer’s disease, childhood cancers, and the biology of aging.

The Icahn School of Medicine is ranked No. 4 in the United States for Cell Biology in the 2026-2027 U.S. News & World Report® Best Global Universities rankings.

Across every investigation, our mission is to identify new approaches to treat human disease and promote healthy aging. With direct access to patient data and biological samples, our breakthroughs can rapidly translate into novel treatments for the patients that need them most.

Collaborative Research and Translational Impact

The Department of Stem Cell Biology and Regenerative Medicine brings together basic researchers, stem cell biologists, and bioengineers, to generate human stem cell-derived cells and organoids. These platforms provide the critical foundation for developing robust human disease models and high-throughput drug screening and advancing therapeutic transplantation techniques.

Our current research portfolio is providing new insights into a broad spectrum of medical conditions, including:

infertility
lung and liver disease
muscle wasting
wound repair
hair loss
congenital diseases affecting the craniofacial, hematopoietic, cardiac, and immune systems
neurodevelopmental conditions such as autism
neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s disease
childhood and adult cancers
and the fundamental processes of aging

Training and Scientific Leadership

We provide an exceptional environment for training the next generation of scientific leaders. Our graduate students and postdoctoral fellows directly engage in cutting-edge research across several model systems and experimental platforms. They benefit from close mentorship and collaboration with our faculty, who are dedicated to fostering scientific curiosity, technical excellence, and innovative thinking—all required to land leadership roles in academia, the biotechnology industry, and clinical medicine.

Led by Sarah Millar, PhD, Dean for Academic and Scientific Affairs; Chair, Department of Stem Cell Biology and Regenerative Medicine; Director, Dean’s Core Facilities, and Professor, Stem Cell Biology and Regenerative Medicine, Dermatology, and Oncological Sciences, Icahn School of Medicine, the Department is focused on advancing regenerative therapies, sustaining excellence in training, and building the knowledge in stem cell and regenerative biology that promises to fundamentally reshape our understanding in, preservation, and restoration of human health.

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Meet the Chair

Sarah Millar, PhD

DEAN FOR ACADEMIC AND SCIENTIFIC AFFAIRS

CHAIR, DEPARTMENT OF STEM CELL BIOLOGY AND REGENERATIVE MEDICINE

DIRECTOR, DEAN’S CORE FACILITIES

PROFESSOR | Stem Cell Biology And Regenerative Medicine

PROFESSOR | Dermatology

PROFESSOR | Oncological Sciences

Discover how Dr. Millar combines pioneering research on epithelial stem cells with a deep commitment to mentorship and diversity in science.

Read the Message From the Chair

Our Research Partners

Every day, we collaborate with several major centers across Mount Sinai—working with surgical teams to develop new procedures and partnering with clinicians to accelerate the translation of stem cell discoveries into better clinical care.

Tisch Cancer Center

Advancing cancer prevention, treatment, and research through a multidisciplinary approach.

The Friedman Brain Institute

Driving research in brain disorders and translating discoveries into new treatments.

Institute for Airway Sciences

Uniting experts across the respiratory system to improve our understanding of airway disease, immunology, and regeneration.

Mindich Institute

Facilitating breakthrough translational research on diseases affecting infants, children, and adolescents.

Mount Sinai Diabetes, Obesity, and Metabolism Institute

Developing better therapies and prevention strategies for diabetes and metabolic disease.

Sinai Skin Biology and Diseases Resource-based Center

Advancing skin biology research through pilot grants, infrastructure, and training.

Department Announcements

The Icahn School of Medicine at Mount Sinai is ranked No. 4 in the United States for Cell Biology in the 2026-2027 S. News & World Report®Best Global Universities rankings.
We are delighted that our faculty members received recognition for their outstanding research at the 2026 Faculty Council Awards Ceremony on June 22, 2026:
- Elvin Wagenblast, PhD, received the Faculty Council Junior Award.
- Andrew Ji, MD, received the Dr. Harold and Golden Lamport Clinical Research Award.
- Many congratulations to Dr. Wagenblast and Dr. Ji for their spectacular achievements