Experimental and Clinical Programs

Cognition, Learning, and Memory Mechanism

The major goal of the Cognition, Learning, and Memory Mechanism work is to understand the molecular, cellular, and circuit mechanisms by which new memories are formed and stored in the brain, as well as how they are retrieved under normal and pathological conditions.

Mark Baxter, PhD (Neuroscience)
Matthew Shapiro, PhD (Neuroscience)

Mood, Anxiety, Stress, and Drug Addiction

The Mood, Anxiety, Stress, and Drug Addiction work’s goal is to understand how memory systems in the brain are corrupted by pathological processes and lead to psychiatric illness, and to devise new means of intervening as a way to develop improved treatments. This work has strong collaborations with the Center of Excellence on Mood and Motivation.

Dennis Charney, MD (Psychiatry)
Yasmin Hurd, PhD (Pharmacology)
Eric Nestler, MD, PhD (Neuroscience)
Antonia New, MD (Psychiatry)

Aging and Memory

The Aging and Memory section’s goal is to understand how memory mechanisms-at the molecular, cellular, and circuit levels-are affected during aging and how it might be possible to interrupt these processes to promote successful aging. This work has strong collaborations with the Center of Excellence on Brain Aging.

Patrick Hof, MD (Neuroscience)
Charles Mobbs, PhD (Neuroscience)
John Morrison, PhD (Neuroscience)
Matthew Shapiro, PhD (Neuroscience)

Alzheimer's and Parkinson's Diseases

The goal of the Alzheimer’s and Parkinson’s Diseases work is to understand how pathological mechanisms involved in neurodegenerative diseases lead to disruption of memory and to use this new knowledge to develop improved treatments of these disorders. This work has strong collaborations with the Center of Excellence on Neurodegeneration.

Joseph Buxbaum, MSc, PhD (Psychiatry)
Dara Dickstein, PhD (Neuroscience)
Samuel Gandy, MD, PhD (Neurology)
Vahram Haroutunian, PhD (Psychiatry)
Patrick Hof, MD (Neuroscience)
John Morrison, PhD (Neuroscience)
Warren Olanow, MD (Neurology)
Dan Perl, MD (Neuropathology)
Stewart Sealfon, MD (Neurology)

Adaptive Plasticity in Neural Circuits

The Adaptive Plasticity in Neural Circuits’ goal is to understand circuit-level adaptations that occur during memory formation, storage, and retrieval in normal and pathological states. This work has strong collaborations with the Center of Excellence on Computational & Systems Neuroscience.

Deanna Benson, PhD (Neuroscience)
Bob Blitzer, PhD (Pharmacology)
Vlad Brezina, PhD (Neuroscience)
Elizabeth Cropper, PhD (Neuroscience)
Ehud Kaplan, PhD (Neuroscience)
Ming-Hu Han (Pharmacology)
George Huntley, PhD (Neuroscience)
Steve Salton, MD, PhD (Neuroscience)
Stewart Sealfon, MD (Neurology)
Klaudiusz Weiss, PhD (Neuroscience)


Contact Us

Matthew Shapiro,PhD
Tel:212-824-8917
Send e-mail

Hess Center for Science and Medicine
9th floor, room 118
1470 Madison Avenue
New York, NY 10029