About the Immunology Institute

The Immunology Institute fosters interdisciplinary, translational research in immunology, immunologic diseases, and transplantation. Mount Sinai’s impressive contributions to immunologic research and to the diagnosis and treatment of immune disorders have brought wide acclaim.

Mount Sinai scientists and clinicians have gained international recognition in areas such as primary immunodeficiency, mucosal immunity, inflammatory bowel disease, allergic diseases, and liver transplantation. Today, Mount Sinai programs in the study and treatment of asthma, arthritis, multiple sclerosis, diabetes, hepatitis C, HIV, and organ transplantation are stronger than ever and still growing.

The Institute builds upon a strong foundation of basic research within the Immunobiology Center and an equally solid program of clinical research and practice in the divisions of clinical immunology within the Departments of Medicine and Pediatrics.

Areas of focus

The Immunology Institute is maximizing the translational aspect of its research by focusing on major immune system functions and diseases. We have designed this strategy to promote interdisciplinary collaboration and the efficient transfer of results into new treatments.

The role of immunity in disease processes can be grouped into four general areas:

  • Autoimmunity
  • Host-pathogen interactions
  • Inflammation and immunoregulation
  • Immunocompetence

Immunology Institute researchers have decided to focus on immunoregulation and immunocompetence, based on Mount Sinai’s expertise in the fields of inflammation, immune deficiency, and immunoregulation. Other determining factors include the existence of a robust patient population, the lack of strong competition within New York City for immunocompromised patients, and substantial potential for extramural funding in these areas, both from the National Institutes of Health and from disease-oriented foundations.

The Immunology Institute will also be home to transplantation research. Developing better immunosuppressant medication for use in organ transplantation and increasing the viability of pancreatic islet cells for transplantation are particularly important areas within the transplant program. Advances in the understanding of immunoregulation and immunocompetence will also have a strong impact.

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